Evolving Genes and Proteins

Evolving Genes and Proteins
Author: Vernon Bryson
Publisher:
Total Pages: 664
Release: 1965
Genre: Biochemistry
ISBN:

Details new perspectives of structural and functional features of proteins and nucleic acids in biochemistry.

Proteins

Proteins
Author: Paulo Almeida
Publisher: Garland Science
Total Pages: 414
Release: 2016-03-14
Genre: Medical
ISBN: 1317285433

Proteins: Concepts in Biochemistry teaches the biochemical concepts underlying protein structure, evolution, stability and folding, and explains how interactions with macromolecular structures determine protein function. Intended for a one-semester biochemistry course with a focus on proteins, this textbook emphasizes the logic underlying biophysical chemical principles. Problems throughout the book encourage statistical and quantitative thinking. The text is ideal for senior undergraduates, first year graduate students, and practitioners in chemistry, biochemistry, biology, and biophysics.

Evolution of the Protein Synthesis Machinery and Its Regulation

Evolution of the Protein Synthesis Machinery and Its Regulation
Author: Greco Hernández
Publisher: Springer
Total Pages: 564
Release: 2016-08-10
Genre: Science
ISBN: 3319394681

The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.

The Origin of Life and Evolutionary Biochemistry

The Origin of Life and Evolutionary Biochemistry
Author: K. Dose
Publisher: Springer Science & Business Media
Total Pages: 459
Release: 2012-12-06
Genre: Science
ISBN: 1468421158

Historical Introduction: A.I. Oparin and the Origin of Life.- Chapters in Honor of "Proiskhozhdenie Zhizni" and A. I, Oparin.- Protein Structure and the Molecular Evolution of Biological Energy Conversion.- Condensation Reactions of Lysine in the Presence of Polyadenylic Acid.- Considerations of the Origin of Spontaneous Mutations.- Pre-Enzymic Emergence of Biochemical Metabolism.- The Methods of Science and the Origins of Life.- Phospholipid Monolayers-As a Prototype of Biological Membranes.- Peptides and Amino Acids in the Primordial Hydrosphere.- Amino Acids and Carbohydrates in Precambria.

Ancestral Sequence Reconstruction

Ancestral Sequence Reconstruction
Author: David A Liberles
Publisher: Oxford University Press
Total Pages: 267
Release: 2007-05-31
Genre: Science
ISBN: 0199299188

Ancestral sequence reconstruction is a technique of growing importance in molecular evolutionary biology and comparative genomics. As a powerful tool for testing evolutionary and ecological hypotheses, as well as uncovering the link between sequence and molecular phenotype, there are potential applications in a range of fields.Ancestral Sequence Reconstruction starts with a historical overview of the field, before discussing the potential applications in drug discovery and the pharmaceutical industry. This is followed by a section on computational methodology, which provides a detailed discussion of the available methods for reconstructing ancestral sequences (including their advantages, disadvantages, and potential pitfalls). Purely computational applications of the technique are then covered, including wholeproteome reconstruction. Further chapters provide a detailed discussion on taking computationally reconstructed sequences and synthesizing them in the laboratory. The book concludes with a description of the scientific questions where experimental ancestral sequence reconstruction has been utilized toprovide insights and inform future research.This research level text provides a first synthesis of the theories, methodologies and applications associated with ancestral sequence recognition, while simultaneously addressing many of the hot topics in the field. It will be of interest and use to both graduate students and researchers in the fields of molecular biology, molecular evolution, and evolutionary bioinformatics.

In the Light of Evolution

In the Light of Evolution
Author: National Academy of Sciences
Publisher:
Total Pages: 388
Release: 2007
Genre: Science
ISBN:

The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.

Protein Engineering

Protein Engineering
Author: Huimin Zhao
Publisher: John Wiley & Sons
Total Pages: 41
Release: 2021-08-23
Genre: Science
ISBN: 3527344705

A one-stop reference that reviews protein design strategies to applications in industrial and medical biotechnology Protein Engineering: Tools and Applications is a comprehensive resource that offers a systematic and comprehensive review of the most recent advances in the field, and contains detailed information on the methodologies and strategies behind these approaches. The authors—noted experts on the topic—explore the distinctive advantages and disadvantages of the presented methodologies and strategies in a targeted and focused manner that allows for the adaptation and implementation of the strategies for new applications. The book contains information on the directed evolution, rational design, and semi-rational design of proteins and offers a review of the most recent applications in industrial and medical biotechnology. This important book: Covers technologies and methodologies used in protein engineering Includes the strategies behind the approaches, designed to help with the adaptation and implementation of these strategies for new applications Offers a comprehensive and thorough treatment of protein engineering from primary strategies to applications in industrial and medical biotechnology Presents cutting edge advances in the continuously evolving field of protein engineering Written for students and professionals of bioengineering, biotechnology, biochemistry, Protein Engineering: Tools and Applications offers an essential resource to the design strategies in protein engineering and reviews recent applications.

Sequence — Evolution — Function

Sequence — Evolution — Function
Author: Eugene V. Koonin
Publisher: Springer Science & Business Media
Total Pages: 482
Release: 2013-06-29
Genre: Science
ISBN: 1475737831

Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.