EQ-5D Value Sets: Inventory, Comparative Review and User Guide

EQ-5D Value Sets: Inventory, Comparative Review and User Guide
Author: Agota Szende
Publisher: Springer Science & Business Media
Total Pages: 96
Release: 2007-03-06
Genre: Medical
ISBN: 1402055110

This book provides an essential guide to the use of the EuroQol Group’s value sets for working with EQ-5D data. The EQ-5D is a widely used generic health state descriptive system and facilitates the valuation of health and health gain through its pre-existing value sets. This book brings together a comprehensive inventory of these value sets and their characteristics and offers guidance on how to choose which value set for what purpose.

Methods for Analysing and Reporting EQ-5D Data

Methods for Analysing and Reporting EQ-5D Data
Author: Nancy Devlin
Publisher: Springer Nature
Total Pages: 114
Release: 2020-08-21
Genre: Medical
ISBN: 3030476227

This open access book is the first published guide about how to analyse data produced by the EQ-5D, one of the most widely used Patient Reported Outcomes questionnaires world wide. The authors provide practical, clear and comprehensive guidance in five concise chapters. Following an overview of the EQ-5D and its analysis, we describe how the questionnaire data – the EQ-5D profile and EQ VAS – can be analysed in different ways to generate important insights into peoples’ health. We then show how the value sets which accompany the EQ-5D can be applied to summarise patients’ data. The final chapter deals with advanced topics, including the use of Minimally Important Differences, case-mix adjustment, mapping, and more. This book is essential for those new to analyzing EQ-5D data and will be also be valuable for those with more experience. The methods can be applied to any EQ-5D instrument (for example, the three- and five-level and Youth versions) and many of the methods described will be equally relevant to other Patient Reported Outcomes instruments.

EQ-5D concepts and methods:

EQ-5D concepts and methods:
Author: Paul Kind
Publisher: Springer Science & Business Media
Total Pages: 272
Release: 2005-10-24
Genre: Medical
ISBN: 9781402037115

Science today makes progress through the imaginative harvesting of knowledge g- erated by the many, rather than as the result of the isolated endeavours of the lone researcher. Innovations in the physical sciences from the development of nuclear te- nologies to the laser, have involved research teams working collectively. Collabo- tion is the rule rather than the exception. In the social sciences this model is all but reversed. Here it is not uncommon to encounter the solitary enthusiast, relishing an independence of spirit and pursuing their own private research agenda. All the more surprising then that a group of researchers from several different disciplines, should have come together in the late 1980s with nothing more substantial on the agenda than that they share their thoughts on the topic of measuring the value of health, or more specifically, on the way that the value of health might vary across different countries. Few scientific enterprises can have begun as cautiously or uncertainly. Few can have developed a cohesion and dynamism that lasted decades and continues to drive ahead after long years of scientific endeavour. Such is the good fortune that befell those of us who came together to form what was later to be known as the Euro- Qol Group. The Group's creation is principally due to the shared professional asso- ation of its members with one man, an economist by training and a visionary academic by inclination and temperament - Alan Williams.

Registries for Evaluating Patient Outcomes

Registries for Evaluating Patient Outcomes
Author: Agency for Healthcare Research and Quality/AHRQ
Publisher: Government Printing Office
Total Pages: 385
Release: 2014-04-01
Genre: Medical
ISBN: 1587634333

This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide
Author: Agency for Health Care Research and Quality (U.S.)
Publisher: Government Printing Office
Total Pages: 236
Release: 2013-02-21
Genre: Medical
ISBN: 1587634236

This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

Value Sets for EQ-5D-5L

Value Sets for EQ-5D-5L
Author: Nancy Devlin
Publisher: Springer Nature
Total Pages: 290
Release: 2022-03-23
Genre: Social Science
ISBN: 3030892891

This open access book provides an essential guide to value sets for anyone working with EQ-5D-5L data. The EQ-5D-5L is one of the most widely used health related quality of life questionnaires around the world, with applications in clinical trials, population health surveys and routine outcomes measurement. In addition to providing a concise, generic way of describing health, the EQ-5D-5L facilitates the valuation of health and health improvements through its value sets, which play a pivotal role in Health Technology Assessment across the world. Value sets for the EQ-5D-5L have been produced in a wide range of countries and regions, using a standardised international protocol developed by the EuroQol Group. This book brings together, for the first time, a comprehensive inventory of these value sets and a comparative review of their characteristics. In addition to the structured summaries of each value set, the book provides clear guidance to users and researchers on how to choose which value set to use, for what purpose. It also provides information about the methods that were used to produce these values, how these methods have been refined and how they may evolve in future. The book is the culmination of a substantial programme of work internationally. By collating these value sets into a single volume, the book aims to provide an easy-to-use resource which is likely to become a key reference source for EQ-5D-5L users and researchers.

Measuring and Valuing Health Benefits for Economic Evaluation

Measuring and Valuing Health Benefits for Economic Evaluation
Author: John Brazier
Publisher: Oxford University Press
Total Pages: 373
Release: 2017
Genre: Business & Economics
ISBN: 0198725922

There are not enough resources in health care systems around the world to fund all technically feasible and potentially beneficial health care interventions. Difficult choices have to be made, and economic evaluation offers a systematic and transparent process for informing such choices. A key component of economic evaluation is how to value the benefits of health care in a way that permits comparison between health care interventions, such as through costs per quality-adjusted life years (QALY). Measuring and Valuing Health Benefits for Economic Evaluation examines the measurement and valuation of health benefits, reviews the explosion of theoretical and empirical work in the field, and explores an area of research that continues to be a major source of debate. It addresses the key questions in the field including: the definition of health, the techniques of valuation, who should provide the values, techniques for modelling health state values, the appropriateness of tools in children and vulnerable groups, cross cultural issues, and the problem of choosing the right instrument. This new edition contains updated empirical examples and practical applications, which help to clarify the readers understanding of real world contexts. It features a glossary containing the common terms used by practitioners, and has been updated to cover new measures of health and wellbeing, such as ICECAP, ASCOT and AQOL. It takes into account new research into the social weighting of a QALY, the rising use of ordinal valuation techniques, use of the internet to collect data, and the use of health state utility values in cost effectiveness models. This is an ideal resource for anyone wishing to gain a specialised understanding of health benefit measurement in economic evaluation, especially those working in the fields of health economics, public sector economics, pharmacoeconomics, health services research, public health, and quality of life research.

Oxford Textbook of Global Public Health

Oxford Textbook of Global Public Health
Author: Roger Detels
Publisher: Oxford University Press
Total Pages: 1717
Release: 2017
Genre: Medical
ISBN: 019881013X

Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology, with 3 volumes comprehensively covering the scope, methods, and practice of the discipline

An Evolutionary Theory of Economic Change

An Evolutionary Theory of Economic Change
Author: Richard R. Nelson
Publisher: Harvard University Press
Total Pages: 456
Release: 1985-10-15
Genre: Business & Economics
ISBN: 9780674041431

This book contains the most sustained and serious attack on mainstream, neoclassical economics in more than forty years. Nelson and Winter focus their critique on the basic question of how firms and industries change overtime. They marshal significant objections to the fundamental neoclassical assumptions of profit maximization and market equilibrium, which they find ineffective in the analysis of technological innovation and the dynamics of competition among firms. To replace these assumptions, they borrow from biology the concept of natural selection to construct a precise and detailed evolutionary theory of business behavior. They grant that films are motivated by profit and engage in search for ways of improving profits, but they do not consider them to be profit maximizing. Likewise, they emphasize the tendency for the more profitable firms to drive the less profitable ones out of business, but they do not focus their analysis on hypothetical states of industry equilibrium. The results of their new paradigm and analytical framework are impressive. Not only have they been able to develop more coherent and powerful models of competitive firm dynamics under conditions of growth and technological change, but their approach is compatible with findings in psychology and other social sciences. Finally, their work has important implications for welfare economics and for government policy toward industry.

Handbook of Disease Burdens and Quality of Life Measures

Handbook of Disease Burdens and Quality of Life Measures
Author: Victor R. Preedy
Publisher: Springer
Total Pages: 758
Release: 2012-12-19
Genre: Medical
ISBN: 9780387786667

This handbook features in-depth reviews of disability-adjusted life years (DALYs), quality-adjusted life years (QALYs), quality of life and financial measures for over 120 diseases and conditions. Its editors have organized this critical information for maximum access and ease of use, with abstracts, definitions of key terms, summary points, and dozens of figures and tables that can enhance the text or stand alone.