Aziridines and Epoxides in Organic Synthesis

Aziridines and Epoxides in Organic Synthesis
Author: Andrei K. Yudin
Publisher: John Wiley & Sons
Total Pages: 532
Release: 2006-02-20
Genre: Science
ISBN: 9783527312139

Aziridines and epoxides are among the most widely used intermediates in organic synthesis, acting as precursors to complex molecules due to the strains incorporated in their skeletons. Besides their importance as reactive intermediates, many biologically active compounds also contain these three-membered rings. Filling a gap in the literature, this clearly structured book presents the much needed information in a compact and concise way. The renowned editor has succeeded in gathering together excellent authors to cover synthesis, applications, and the biological aspects in equal depth. Divided roughly equally between aziridines and epoxides, the twelve chapters discuss: * Synthesis of aziridines * Nucleophilic ring-opening of aziridines and epoxides * Organic synthesis with aziridine building blocks * Vinyl aziridines in organic synthesis * Diastereoselective aziridination reagents * Synthetic aspects of aziridinomitocene chemistry * Biosynthesis of biologically important aziridines * Organic catalysis of epoxide and aziridine ring formation * Metal-mediated synthesis of epoxides * Asymmetric epoxide ring opening chemistry * Epoxides in complex molecule synthesis * Biological activity of epoxide-containing molecules A high-quality reference manual for academic and industrial chemists alike.

Comprehensive Organic Functional Group Transformations

Comprehensive Organic Functional Group Transformations
Author: Alan R. Katritzky
Publisher: Elsevier
Total Pages: 1452
Release: 1995
Genre: Mathematics
ISBN: 9780080423227

This Volume covers the formation of carbon-carbon single-, double- and triple bonds by substitution and addition reactions as well as by various rearrangements. The formation of carbon-carbon multiple bonds by elimination and condensation procedures is fully documented. In addition the synthesis of carbon-hydrogen bonds principally by substitution and addition reactions is featured as is the preparation of a wide variety of carbon-centred anions, cations and radicals.

The Determination of Epoxide Groups

The Determination of Epoxide Groups
Author: B. Dobinson
Publisher: Elsevier
Total Pages: 88
Release: 2013-10-22
Genre: Science
ISBN: 1483150534

The Determination of Epoxide Groups describes the advantages and limitations of the methods for determination of 1,2-epoxide groups of various kinds. Chapter 1 examines the chemical reactivities of different epoxides under various conditions, which is of fundamental importance in the choice of the analytical method to be used. Chapter 2 explores most of the analytical work on epoxides involving ring-opening with HCl or HBr. Chapter 3 deals with the alternative techniques involving quantitative rearrangement of epoxides, or ring-opening under non-acidic conditions. This chapter also contains descriptions of various miscellaneous analytical techniques, including very sensitive methods, as well as the use of infrared spectroscopic techniques for analysis of epoxides and the study of their reactions, particularly the cure of epoxy resins. Chapter 4 summarizes the advantages and limitations of the various methods, along with the main factors affecting choice of experimental. This book is of great value to analytical and organic chemists, researchers, and students.

Organic Azides

Organic Azides
Author: Stefan Bräse
Publisher: John Wiley & Sons
Total Pages: 537
Release: 2010-02-01
Genre: Science
ISBN: 0470519983

Most current state-of-the-art overview of this important class of compounds, encompassing many new and emerging applications The number of articles on organic azides continues to increase tremendously; on average, there are more than 1000 new publications a year Covers basic chemistry as well as state-of-the-art applications in life science and materials science World-ranked authors describe their own research in the wider context of azide chemistry Includes a chapter on safe synthesis and handling (azides can decompose explosively)

Fundamentals of Asymmetric Catalysis

Fundamentals of Asymmetric Catalysis
Author: Patrick J. Walsh
Publisher: University Science Books
Total Pages: 692
Release: 2009-01-02
Genre: Science
ISBN: 9781891389542

This work describes the essential aspects of enantioselective catalysis, with chapters organised by concept rather than by reaction type. Each concept is supported by examples to give the reader broad exposure to a wide range of catalysts, reactions and reaction mechanisms.

Comprehensive Chirality

Comprehensive Chirality
Author:
Publisher: Newnes
Total Pages: 5635
Release: 2012-12-31
Genre: Science
ISBN: 0080951686

Although many books exist on the subject of chiral chemistry, they only briefly cover chiral synthesis and analysis as a minor part of a larger work, to date there are none that pull together the background information and latest advances in one comprehensive reference work. Comprehensive Chirality provides a complete overview of the field, and includes chiral research relevant to synthesis, analytic chemistry, catalysis, and pharmaceuticals. The individual chapters in each of the 9 volumes provide an in depth review and collection of references on definition, technology, applications and a guide/links to the related literature. Whether in an Academic or Corporate setting, these chapters will form an invaluable resource for advanced students/researchers new to an area and those who need further background or answers to a particular problem, particularly in the development of drugs. Chirality research today is a central theme in chemistry and biology and is growing in importance across a number of disciplinary boundaries. These studies do not always share a unique identifying factor or subject themselves to clear and concise definitions. This work unites the different areas of research and allows anyone working or researching in chiral chemistry to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding. The field of chirality counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Chirality fills this vacuum, and can be considered the definitive work. It will help users apply context to the diverse journal literature offering and aid them in identifying areas for further research and/or for solving problems. Chief Editors, Hisashi Yamamoto (University of Chicago) and Erick Carreira (ETH Zürich) have assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource.

General and Synthetic Methods

General and Synthetic Methods
Author: G. Pattenden
Publisher: Royal Society of Chemistry
Total Pages: 617
Release: 1994-01-28
Genre:
ISBN: 0851868347

Annotation. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

Chemical Sensitivity, Volume I

Chemical Sensitivity, Volume I
Author: William J. Rea
Publisher: CRC Press
Total Pages: 554
Release: 2023-07-28
Genre: Science
ISBN: 1000945847

Chemical Sensitivity is the first major scientific book series on chemical sensitivity, an increasingly important worldwide health problem. This four-volume series features results from the study of more than 20,000 environmentally sensitive patients at the Environmental Health Center (EHC) in Dallas. Results from the study at EHC are supplemented by information accumulated from the treatment and study of an estimated 100,000 patients by other environmentally oriented physicians and scientists around the world.