Organic Chemistry of Enzyme-Catalyzed Reactions, Revised Edition

Organic Chemistry of Enzyme-Catalyzed Reactions, Revised Edition
Author: Richard B. Silverman
Publisher: Elsevier
Total Pages: 736
Release: 2002-03-07
Genre: Technology & Engineering
ISBN: 0080513360

The Organic Chemistry of Enzyme-Catalyzed Reactions is not a book on enzymes, but rather a book on the general mechanisms involved in chemical reactions involving enzymes. An enzyme is a protein molecule in a plant or animal that causes specific reactions without itself being permanently altered or destroyed. This is a revised edition of a very successful book, which appeals to both academic and industrial markets. - Illustrates the organic mechanism associated with each enzyme-catalyzed reaction - Makes the connection between organic reaction mechanisms and enzyme mechanisms - Compiles the latest information about molecular mechanisms of enzyme reactions - Accompanied by clearly drawn structures, schemes, and figures - Includes an extensive bibliography on enzyme mechanisms covering the last 30 years - Explains how enzymes can accelerate the rates of chemical reactions with high specificity - Provides approaches to the design of inhibitors of enzyme-catalyzed reactions - Categorizes the cofactors that are appropriate for catalyzing different classes of reactions - Shows how chemical enzyme models are used for mechanistic studies - Describes catalytic antibody design and mechanism - Includes problem sets and solutions for each chapter - Written in an informal and didactic style

Enzymes in Synthetic Organic Chemistry

Enzymes in Synthetic Organic Chemistry
Author: Chi-Huey Wong
Publisher: Elsevier
Total Pages: 392
Release: 1994-07
Genre: Science
ISBN: 9780080359410

Covering the recent development in enzymatic organic synthesis, this text focuses on the use of isolated enzymes. It includes a discussion of the characteristics of enzymes as catalysts and different types of chemical transformations.

Organic Synthesis Using Biocatalysis

Organic Synthesis Using Biocatalysis
Author: Animesh Goswami
Publisher: Academic Press
Total Pages: 440
Release: 2015-09-06
Genre: Science
ISBN: 012411542X

Organic Synthesis Using Biocatalysis provides a concise background on the application of biocatalysis for the synthesis of organic compounds, including the important biocatalytic reactions and application of biocatalysis for the synthesis of organic compounds in pharmaceutical and non-pharmaceutical areas. The book provides recipes for carrying out various biocatalytic reactions, helping both newcomers and non-experts use these methodologies. It is written by experts in their fields, and provides both a current status and future prospects of biocatalysis in the synthesis of organic molecules. - Provides a concise background of the application of biocatalysis for the synthesis of organic compounds - Expert contributors present recipes for carrying out biocatalytic reactions, including subject worthy discussions on biocatalysis in organic synthesis, biocatalysis for selective organic transformation, enzymes as catalysis for organic synthesis, biocatalysis in Industry, including pharmaceuticals, and more - Contains detailed, separate chapters that describe the application of biocatalysis

New Enzymes for Organic Synthesis

New Enzymes for Organic Synthesis
Author: Thomas Scheper
Publisher: Springer Science & Business Media
Total Pages: 256
Release: 1999-04
Genre: Science
ISBN: 9783540655497

Isolated enzymes are known as useful for synthesising of complex molecules with more and more large scale applications in recent years. These six reviews show different steps in the development of enzymatic syntheses for useful compounds. Screening of novel enzymes, their biochemical characterisation as well as reaction engineering approaches in order to increase their performance are treated in three papers. Then the use of protein design as a tool for the directed improvement of reactivity and selectivity of biocatalysts is described in two reviews. The supply of sufficient quantities of biocatalysts must not be neglected: fluidized bed adsorption as an emerging technology for the simple and fast purification of biomolecules is presented in the light of its potential in large scale supply of enzyme catalysts.

Directed Evolution of Selective Enzymes

Directed Evolution of Selective Enzymes
Author: Manfred T. Reetz
Publisher: John Wiley & Sons
Total Pages: 320
Release: 2016-12-19
Genre: Science
ISBN: 3527316604

Authored by one of the world's leading organic chemists, this authoritative reference provides an overview of basic strategies in directed evolution and introduces common gene mutagenesis, screening and selection methods. Throughout the text, emphasis is placed on methodology development to maximize efficiency, reliability and speed of the experiments and to provide guidelines for efficient protein engineering. Professor Reetz highlights the application of directed evolution experiments to address limitations in the field of enzyme selectivity, substrate scope, activity and robustness. He critically reviews recent developments and case studies, takes a look at future applications in the field of organic synthesis, and concludes with lessons learned from previous experiments.

Enzymes in Organic Synthesis

Enzymes in Organic Synthesis
Author: Ruth Porter
Publisher: John Wiley & Sons
Total Pages: 192
Release: 2009-09-14
Genre: Science
ISBN: 0470718625

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Enzymes as Catalysts in Organic Synthesis

Enzymes as Catalysts in Organic Synthesis
Author: Manfred P. Schneider
Publisher: Springer Science & Business Media
Total Pages: 422
Release: 2012-12-06
Genre: Science
ISBN: 9400946864

Proceedings of the NATO Advanced Research Workshop, Reisensburg/Ulm, Donau, Germany, June 16-22, 1985

Sustainable Organic Synthesis

Sustainable Organic Synthesis
Author: Dr Stefano Protti
Publisher: Royal Society of Chemistry
Total Pages: 602
Release: 2021-10-29
Genre: Science
ISBN: 1839162031

Recent years have seen huge growth in the area of sustainable chemistry. In order to meet the chemical needs of the global population whilst minimising impacts on health and the environment it is essential to keep reconsidering and improving synthetic processes. Sustainable Organic Synthesis is a comprehensive collection of contributions, provided by specialists in Green Chemistry, covering topics ranging from catalytic approaches to benign and alternative reaction media, and innovative and more efficient technologies.

Asymmetric Organic Synthesis with Enzymes

Asymmetric Organic Synthesis with Enzymes
Author: Vicente Gotor
Publisher: John Wiley & Sons
Total Pages: 340
Release: 2008-09-08
Genre: Science
ISBN: 3527622497

Perfect for biochemists, synthetic and organic chemists, this book covers all important reactions, including C-C coupling reactions, oxidation reactions and many more. Divided into two parts, the first section on methodology presents new innovative methods for enzymatic catalysis optimization, including such new trends as medium engineering, directed evolution and computer-aided prediction of enantioselectivity. The second and main section deals with applications to synthesis, showing important reaction types and their applications. Only those reactions with very high selectivity are presented, allowing readers to improve their own reaction yields.