Enzyme Mechanism From Isotope Effects
Download Enzyme Mechanism From Isotope Effects full books in PDF, epub, and Kindle. Read online free Enzyme Mechanism From Isotope Effects ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author | : Paul F. Cook |
Publisher | : CRC Press |
Total Pages | : 656 |
Release | : 1991-09-20 |
Genre | : Medical |
ISBN | : 9780849353123 |
Isotope effects have become one of the most powerful tools available to the enzymologist for probing enzymic mechanisms. Enzyme Mechanism from Isotope Effects presents the basic theory underlying isotope effects, including the latest findings on proton tunneling and coupled atomic notions. Specific theoretical applications are emphasized in regard to the types of information that can be obtained using isotope effects. The book also examines recent theoretical treatments of the product dependence of deuterium isotope effects, multiple isotope effects and isotope effects on intermediate partitioning. Other topics include a complete discussion of methods for measuring isotope effects, including a detailed description of the use of the isotope ratio mass spectrometer to obtain isotope effects, and a review of the literature regarding mechanistic information obtained from isotope effects for individual classes of enzyme-catalyzed reactions. Enzyme Mechanism from Isotope Effects is an excellent reference source for investigators using isotope effects in their research. The book is also valuable for reference libraries and instructors teaching courses in enzyme mechanism.
Author | : William Wallace Cleland |
Publisher | : |
Total Pages | : 328 |
Release | : 1977 |
Genre | : Science |
ISBN | : |
Author | : |
Publisher | : Academic Press |
Total Pages | : 634 |
Release | : 2017-09-12 |
Genre | : Medical |
ISBN | : 0128122749 |
Experimental Analysis of Enzyme Mechanism Using Isotope Effects, Volume 596, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this comprehensive update include Measurement of enzyme binding isotope effects, Chemical ligation and isotope labeling to locate dynamic effects, Measurement of heavy enzyme isotope effects, Extracting kinetic isotope effects from a global analysis of reaction progress curves, KIE of metabolic flux and enzymes, Solvent and Primary KIE on Flavin Enzymes, and The Rapid Determination of Primary Deuterium Isotope Effects on Enzyme-Catalyzed Proton Transfer at Carbon in 50/50 HOH/DOD. Readers who are interested in applying or understanding this research will find useful methods currently used for measuring isotope effects on solution and enzyme reactions. Written by pioneers of modern isotope effect research Is the only collection of modern kinetic isotope effect methods currently available
Author | : John Sears Blanchard |
Publisher | : |
Total Pages | : 662 |
Release | : 1979 |
Genre | : Enzymes |
ISBN | : |
Author | : Jeffrey D. Hermes |
Publisher | : |
Total Pages | : 506 |
Release | : 1983 |
Genre | : Enzymes |
ISBN | : |
Author | : Paul Martin Karl Weiss |
Publisher | : |
Total Pages | : 342 |
Release | : 1987 |
Genre | : |
ISBN | : |
Author | : Amnon Kohen |
Publisher | : CRC Press |
Total Pages | : 1092 |
Release | : 2005-11-01 |
Genre | : Medical |
ISBN | : 1420028022 |
The field of isotope effects has expanded exponentially in the last decade, and researchers are finding isotopes increasingly useful in their studies. Bringing literature on the subject up to date, Isotope Effects in Chemistry and Biology covers current principles, methods, and a broad range of applications of isotope effects in the physical, biolo
Author | : Mark Alan Rishavy |
Publisher | : |
Total Pages | : 182 |
Release | : 2000 |
Genre | : |
ISBN | : |
Author | : Steven Rosenberg |
Publisher | : |
Total Pages | : 692 |
Release | : 1978 |
Genre | : |
ISBN | : |
Author | : Paul F. Cook |
Publisher | : Garland Science |
Total Pages | : 346 |
Release | : 2007-03-06 |
Genre | : Medical |
ISBN | : 1136844279 |
Enzyme Kinetics and Mechanism is a comprehensive textbook on steady-state enzyme kinetics. Organized according to the experimental process, the text covers kinetic mechanism, relative rates of steps along the reaction pathway, and chemical mechanism—including acid-base chemistry and transition state structure. Practical examples taken from the literature demonstrate theory throughout. The book also features numerous general experimental protocols and how-to explanations for interpreting kinetic data. Written in clear, accessible language, the book will enable graduate students well-versed in biochemistry to understand and describe data at the fundamental level. Enzymologists and molecular biologists will find the text a useful reference.