Microbial Cell Factories Engineering for Production of Biomolecules

Microbial Cell Factories Engineering for Production of Biomolecules
Author: Vijai Singh
Publisher: Academic Press
Total Pages: 490
Release: 2021-02-13
Genre: Science
ISBN: 0128214783

Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. - Offers basic understanding and a clear picture of various MCFs - Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others - Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications - Highlights the advances, challenges, and future opportunities in designing MCFs

Polymer Chemistry

Polymer Chemistry
Author: Andrew J. Peacock
Publisher: Carl Hanser Verlag GmbH Co KG
Total Pages: 420
Release: 2012-11-12
Genre: Technology & Engineering
ISBN: 3446433430

This book provides a comprehensive introduction to the study of polymers. Special emphasis is given to the characteristics that set polymers apart from small molecules, as studied in classic chemistry courses. The various branches of polymer science are introduced and discussed in a systematic manner, starting from basic chemical structures, continuing through supermolecular organization and physical properties. Specific examples are used throughout to illustrate how end usage relates to the principles under discussion. A series of chapters is devoted to case studies describing the principal classes of synthetic polymers. Content includes: - Polymerization - Characterization of Polymers - Rheological Description of Polymer Melts - Structural Development - Properties - Compounding and Extrusion Processes - Molding processes - Additional Methods of Manufacture - Commodity Polymers - Engineering Thermoplastics - Neat Stuff

Polyhydroxyalkanoates--plastic Materials of the 21st Century

Polyhydroxyalkanoates--plastic Materials of the 21st Century
Author: Tatʹi͡ana Grigorʹevna Volova
Publisher: Nova Publishers
Total Pages: 310
Release: 2004
Genre: Medical
ISBN: 9781590339923

Special Interest Catogories: biotechnology; materials science; medicine; ecology and chemistry. The book summarizes the literature data and research results on biodegradable polyesters of microbiological origin -- polymers of hydroxy alkanoic acids (polyhydroxyalkanoates, PHAs). These polymers are thermoplastic, biodegradable, and biocompatible. They are promising candidates for applications in agriculture, communal services, pharmacology, medicine, and other spheres. The book sums up the most recent data on the known types of polyhydroxyalkanoates, their producers, substrates, and methods of biosynthesis. The structure and physicochemical properties of these polymers, the methods used to process them to make specialised products and spheres of their application are described in the book.

Biomolecular Engineering Solutions for Renewable Specialty Chemicals

Biomolecular Engineering Solutions for Renewable Specialty Chemicals
Author: R. Navanietha Krishnaraj
Publisher: John Wiley & Sons
Total Pages: 484
Release: 2021-12-09
Genre: Technology & Engineering
ISBN: 1119771927

Discover biomolecular engineering technologies for the production of biofuels, pharmaceuticals, organic and amino acids, vitamins, biopolymers, surfactants, detergents, and enzymes In Biomolecular Engineering Solutions for Renewable Specialty Chemicals, distinguished researchers and editors Drs. R. Navanietha Krishnaraj and Rajesh K. Sani deliver a collection of insightful resources on advanced technologies in the synthesis and purification of value-added compounds. Readers will discover new technologies that assist in the commercialization of the production of value-added products. The editors also include resources that offer strategies for overcoming current limitations in biochemical synthesis, including purification. The articles within cover topics like the rewiring of anaerobic microbial processes for methane and hythane production, the extremophilic bioprocessing of wastes to biofuels, reverse methanogenesis of methane to biopolymers and value-added products, and more. The book presents advanced concepts and biomolecular engineering technologies for the production of high-value, low-volume products, like therapeutic molecules, and describes methods for improving microbes and enzymes using protein engineering, metabolic engineering, and systems biology approaches for converting wastes. Readers will also discover: A thorough introduction to engineered microorganisms for the production of biocommodities and microbial production of vanillin from ferulic acid Explorations of antibiotic trends in microbial therapy, including current approaches and future prospects, as well as fermentation strategies in the food and beverage industry Practical discussions of bioactive oligosaccharides, including their production, characterization, and applications In-depth treatments of biopolymers, including a retrospective analysis in the facets of biomedical engineering Perfect for researchers and practicing professionals in the areas of environmental and industrial biotechnology, biomedicine, and the biological sciences, Biomolecular Engineering Solutions for Renewable Specialty Chemicals is also an invaluable resource for students taking courses involving biorefineries, biovalorization, industrial biotechnology, and environmental biotechnology.

Biopolyesters

Biopolyesters
Author: Wolfgang Babel
Publisher: Springer
Total Pages: 345
Release: 2003-07-01
Genre: Technology & Engineering
ISBN: 3540400214

Living systems synthesize seven different classes of polymers. They provide structure and form for cells and organisms, function as catalysts and energy storage and carry the genetic information. All these polymers possess technically interesting properties. Some of these biopolymers are already used commercially. This special volume of Advances in Biochemical Engineering/Biotechnology comprises 10 chapters. It gives an overview of the water insoluble biopolyesters, in particular of the microbially synthesized poly-hydroxyalkanoate (PHA) family. It reports the state of the art of metabolism, regulation and genetic background, the latest advances made in genetic optimization of bacteria, "construction" of transgenic plants and in vitro synthesis by means of purified enzymes. Furthermore, it describes relevant technologies and evaluates perspectives concerning increasing the economic viability and competitiveness of PHA and discusses applications in medicine, packaging, food and other fields.

Plastics from Bacteria

Plastics from Bacteria
Author: George Guo-Qiang Chen
Publisher: Springer Science & Business Media
Total Pages: 453
Release: 2009-12-02
Genre: Science
ISBN: 3642032877

Due to the possibility that petroleum supplies will be exhausted in the next decades to come, more and more attention has been paid to the production of bacterial pl- tics including polyhydroxyalkanoates (PHA), polylactic acid (PLA), poly(butylene succinate) (PBS), biopolyethylene (PE), poly(trimethylene terephthalate) (PTT), and poly(p-phenylene) (PPP). These are well-studied polymers containing at least one monomer synthesized via bacterial transformation. Among them, PHA, PLA and PBS are well known for their biodegradability, whereas PE, PTT and PPP are probably less biodegradable or are less studied in terms of their biodegradability. Over the past years, their properties and appli- tions have been studied in detail and products have been developed. Physical and chemical modifications to reduce their cost or to improve their properties have been conducted. PHA is the only biopolyester family completely synthesized by biological means. They have been investigated by microbiologists, molecular biologists, b- chemists, chemical engineers, chemists, polymer experts, and medical researchers for many years. PHA applications as bioplastics, fine chemicals, implant biomate- als, medicines, and biofuels have been developed. Companies have been est- lished for or involved in PHA related R&D as well as large scale production. It has become clear that PHA and its related technologies form an industrial value chain in fermentation, materials, feeds, and energy to medical fields.

Biorefinery

Biorefinery
Author: Juan-Rodrigo Bastidas-Oyanedel
Publisher: Springer
Total Pages: 756
Release: 2019-04-15
Genre: Technology & Engineering
ISBN: 3030109615

This book discusses the biorefinery of biomass feedstocks. In-depth chapters highlight the scientific and technical aspects and present a techno-economic analysis of such systems. By using a TEA approach, the authors present feasible pathways for the conversion of biomass (both residual biomass, energy crops, and algae biomass), showing the different possibilities for the production of biochemical materials, biofuels, and fertilizers. The concepts presented in this book will link companies, investors, and governments by providing a framework that will help reduce pollutants and create a biomass-related economy that incorporates the newest developments and technologies in the area.