Engineering the Knee Meniscus

Engineering the Knee Meniscus
Author: Kyriacos Athanasiou
Publisher: Springer Nature
Total Pages: 90
Release: 2022-05-31
Genre: Science
ISBN: 3031025768

The knee meniscus was once thought to be a vestigial tissue, but is now known to be instrumental in imparting stability, shock absorption, load transmission, and stress distribution within the knee joint. Unfortunately, most damage to the meniscus cannot be effectively healed by the body. Meniscus tissue engineering offers a possible solution to this problem by striving to create replacement tissue that may be implanted into a defect site. With a strong focus on structure-function relationships, this book details the essential anatomical, biochemical, and mechanical aspects of this versatile tissue and reviews current meniscus tissue engineering strategies and repair techniques. We have written this text such that undergraduate students, graduate students, and researchers will find it useful as a first foray into tissue engineering, a cohesive study of the meniscus, or a reference for meniscus engineering specifications. Table of Contents: Structure-Function Relationships of the Knee Meniscus / Pathophysiology and the Need for Tissue Engineering / Tissue Engineering of the Knee Meniscus / Current Therapies and Future Directions

Engineering the Knee Meniscus

Engineering the Knee Meniscus
Author: Kyriacos A. Athanasiou
Publisher: Morgan & Claypool Publishers
Total Pages: 98
Release: 2009
Genre: Electronic books
ISBN: 1598298720

The knee meniscus was once thought to be a vestigial tissue, but is now known to be instrumental in imparting stability, shock absorption, load transmission, and stress distribution within the knee joint. Unfortunately, most damage to the meniscus cannot be effectively healed by the body. Meniscus tissue engineering offers a possible solution to this problem by striving to create replacement tissue that may be implanted into a defect site. With a strong focus on structure-function relationships, this book details the essential anatomical, biochemical, and mechanical aspects of this versatile tissue and reviews current meniscus tissue engineering strategies and repair techniques. We have written this text such that undergraduate students, graduate students, and researchers will find it useful as a first foray into tissue engineering, a cohesive study of the meniscus, or a reference for meniscus engineering specifications. Table of Contents: Structure-Function Relationships of the Knee Meniscus / Pathophysiology and the Need for Tissue Engineering / Tissue Engineering of the Knee Meniscus / Current Therapies and Future Directions

The Meniscus

The Meniscus
Author: Philippe Beaufils
Publisher: Springer Science & Business Media
Total Pages: 397
Release: 2010-04-28
Genre: Medical
ISBN: 3642024505

This guide focuses on the normal meniscal mechanism, body and function. Meniscal pathology and therapy are depicted in detail, followed by a presentation of long-term experience of meniscal transplantation and a look into the future of meniscal surgery.

Sports Injuries

Sports Injuries
Author: Mahmut Nedim Doral
Publisher: Springer Nature
Total Pages: 3295
Release: 2015-06-29
Genre: Medical
ISBN: 3642365698

Sports Injuries: Prevention, Diagnosis, Treatment and Rehabilitation covers the whole field of sports injuries and is an up-to-date guide for the diagnosis and treatment of the full range of sports injuries. The work pays detailed attention to biomechanics and injury prevention, examines the emerging treatment role of current strategies and evaluates sports injuries of each part of musculoskeletal system. In addition, pediatric sports injuries, extreme sports injuries, the role of physiotherapy, and future developments are extensively discussed. All those who are involved in the care of patients with sports injuries will find this textbook to be an invaluable, comprehensive, and up-to-date reference.

Imaging of Arthritis and Metabolic Bone Disease E-Book

Imaging of Arthritis and Metabolic Bone Disease E-Book
Author: Barbara N. W. Weissman
Publisher: Elsevier Health Sciences
Total Pages: 770
Release: 2009-05-09
Genre: Medical
ISBN: 0323074685

Get state-of-the-art coverage of the full range of imaging techniques available to assist in the diagnosis and therapeutic management of rheumatic diseases. Written by acknowledged experts in musculoskeletal imaging, this richly illustrated, full-color text presents the latest diagnostic and disease monitoring modalities - MRI, CT, ultrasonography, nuclear medicine, DXA — as well as interventional procedures. You'll find comprehensive coverage of specific rheumatic conditions, including osteoarticular and extraarticular findings. This superb new publication puts you at the forefront of imaging in arthritis and metabolic bone disease — a must have reference for the clinician and imaging specialist. Includes all imaging modalities relevant to rheumatic disease, and applications and contraindications of each, for balanced coverage. Incorporates a user-friendly, consistent full-color format for quick and easy reference. Provides osteoarticular and extra-articular features and findings to show how imaging benefits diagnosis and management of complex rheumatologic conditions. Creates a one-stop shop with comprehensive coverage of imaging for all rheumatic conditions, including metabolic conditions and pediatric disorders. Presents interventional techniques—injections, arthrography, radiofrequency ablation—to create the perfect diagnostic and interventional clinical tool.

Cartilage Injury of the Knee

Cartilage Injury of the Knee
Author: Aaron J. Krych
Publisher: Springer Nature
Total Pages: 345
Release: 2021-08-31
Genre: Medical
ISBN: 3030780511

Cartilage injuries of the knee are common, and diagnosis and treatment options have continued to evolve. This book focuses on current non-operative and surgical treatment strategies for articular cartilage injuries, highlighting the controversies and different approaches from an international perspective. This book includes information on the basic science of cartilage structure and function, expert perspectives on imaging and diagnosing, as well as work-up of athletes and patients presenting with acute or chronic cartilage injury. It also provides an evidence base for current cutting-edge cartilage repair and restoration. Written by leading experts in the field, the book, published in collaboration with ISAKOS and ICRS, is vital reading for orthopaedic and sports medicine surgeons, fellows and residents. It is also of interest to sports trainers, physiotherapists, medical students, postgraduate students, and physical medicine and rehabilitation specialists.

The Menisci

The Menisci
Author: Robert F. LaPrade
Publisher: Springer
Total Pages: 198
Release: 2017-02-21
Genre: Medical
ISBN: 3662537923

This book is a comprehensive journey through the pathogenesis and treatment of meniscal pathology. It details the elements that are necessary to properly understand, diagnose, and treat meniscal tears, ranging from vertical tears to radial tears and root avulsions. Treatment techniques are thoroughly described and illustrated, with presentation of the latest evidence on outcomes. The algorithmic treatment of meniscal tears has undergone a rapid transformation. We have progressed from the initial treatments involving removal of the meniscus using an open technique, to the performance of partial meniscectomies and complex meniscal repairs by means of an arthroscopic technique. The current treatment goal is to maintain the biology and mechanical integrity of this vital knee structure, an aim too often disregarded by past generations of surgeons. An explosion of new knowledge, coupled with advances in arthroscopic and surgical technology, has paved the way for wider application of approaches that help to preserve the meniscus, in the hope of preventing or delaying the development of knee arthritis. This book will have utility for all clinicians who treat meniscal lesions and will serve as a valuable resource for years to come.

Regenerative Strategies for the Treatment of Knee Joint Disabilities

Regenerative Strategies for the Treatment of Knee Joint Disabilities
Author: Joaquim Miguel Oliveira
Publisher: Springer
Total Pages: 406
Release: 2016-09-26
Genre: Technology & Engineering
ISBN: 3319447858

This book presents regenerative strategies for the treatment of knee joint disabilities. The book is composed of four main sections totaling 19 chapters which review the current knowledge on the clinical management and preclinical regenerative strategies. It examines the role of different natural-based biomaterials as scaffolds and implants for addressing different tissue lesions in the knee joint. Section one provides an updated and comprehensive discussion on articular cartilage tissue regeneration. Section two focuses on the important contributions for bone and osteochondral tissue engineering. Section three overview the recent advances on meniscus repair/regeneration strategies. Finally, section four further discusses the current strategies for treatment of ligament lesions. Each chapter is prepared by world know expert on their fields, so we do firmly believe that the proposed book will be a reference in the area of biomaterials for regenerative medicine.

In Situ Tissue Regeneration

In Situ Tissue Regeneration
Author: Sang Jin Lee
Publisher: Academic Press
Total Pages: 460
Release: 2016-07-17
Genre: Medical
ISBN: 012802500X

In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the body's ability to mobilize endogenous stem cells to the site of injury and details the latest strategies developed for inducing and supporting the body's own regenerating capacity. From the perspective of regenerative medicine and tissue engineering, this book describes the mechanism of host cell recruitment, cell sourcing, cellular and molecular roles in cell differentiation, navigational cues and niche signals, and a tissue-specific smart biomaterial system that can be applied to a wide range of therapies. The work is divided into four sections to provide a thorough overview and helpful hints for future discoveries: endogenous cell sources; biochemical and physical cues; smart biomaterial development; and applications. - Explores the body's ability to mobilize endogenous stem cells to the site of injury - Details the latest strategies developed for inducing and supporting the body's own regenerating capacity - Presents smart biomaterials in cell-based tissue engineering applications—from the cell level to applications—in the first unified volume - Features chapter authors and editors who are authorities in this emerging field - Prioritizes a discussion of the future direction of smart biomaterials for in situ tissue regeneration, which will affect an emerging and lucrative industry

Articular Cartilage Tissue Engineering

Articular Cartilage Tissue Engineering
Author: Kyriacos A. Athanasiou
Publisher: Morgan & Claypool Publishers
Total Pages: 183
Release: 2010
Genre: Medical
ISBN: 1598298755

Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage's low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analysis on the United States Food and Drug Administration regulatory pathways that products must follow to market. This book was written to serve as a reference for researchers seeking to learn about articular cartilage, for undergraduate and graduate level courses, and as a compendium of articular cartilage tissue engineering design criteria. Table of Contents: Hyaline Articular Cartilage / Cartilage Aging and Pathology / In Vitro / Bioreactors / Future Directions