This text is meant for introductory and midlevel program and project managers, Systems Engineering (SE), Technology Management (TM) and Engineering Management (EM) professionals. This includes support personnel who underpin and resource programs and projects. Anyone who wishes to understand what SE, TM and EM are, how they work together, what their differences are, when they should be used and what benefits should be expected, will find this text an invaluable resource. It will also help students to understand the career paths in innovation and entrepreneurship to choose from. There is considerable confusion today on when and where to use each discipline, and how they should be applied to individual circumstances. This text provides practitioners with the guidelines necessary to know when to use a specific discipline, how to use them and what results to expect. The text clearly shows how the disciplines retain focus of goals and targets, using cost, scope, schedule and risk to their advantage, while complying with and informing investors, oversight and those related personnel who eventually govern corporate or government decisions. It is more of an entry and midlevel general overview instructing the reader how to use the disciplines and when to use them. To use them all properly, more in-depth study is always necessary. However, the reader will know when to start, where to go and what disciplines to employ depending on the product, service, market, infrastructure, system or service under consideration. To date, none of this is available in existing literature. All texts on the subject stretch to try and cover all things, which is simply not possible, even with the definitions assigned by the three disciplines.