Endogenous Sleep Substances and Sleep Regulation

Endogenous Sleep Substances and Sleep Regulation
Author: Shojiro Inoué
Publisher: VSP
Total Pages: 284
Release: 1985-12
Genre: Science
ISBN: 9789067640589

This volume provides the first major overview, by eminent authorities on the subject, of recent developments in the field of endogenous substances and their regulation of sleep processes. The first two sections discuss general aspects of sleep regulation; including an historical overview, the restorative and adaptive functions of sleep, and evolutionary features. The third section contains contributions focussing on circadian rhythms in relation to humoral factors, hormones, neurotransmitters and metabolism. The sleep substances currently receiving most attention --- delta-sleep-inducing-peptide (DSIP), muramyl peptides, interleukin-1, sleep-promoting substance (SPS) and prostaglandin D2 --- are extensively discussed. Substances that may selectively modulate REM sleep are dealt with in the final section.

Sleep Disorders and Sleep Deprivation

Sleep Disorders and Sleep Deprivation
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 425
Release: 2006-10-13
Genre: Medical
ISBN: 0309101115

Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.

Biology of Sleep Substances

Biology of Sleep Substances
Author: Shojiro Inoue
Publisher: CRC Press
Total Pages: 220
Release: 2020-08-11
Genre: Medical
ISBN: 1000141586

All aspects of sleep sciences are included in this excellent resource text, with special reference to sleep substances and sleep modulators. The historical development of the theories of sleep are reviewed in conjunction with the technical problems. All candidate substances are overviewed as to their sites of presence, chemical nature, bioassay techniques, physiological and pharmacological effects. On the basis of a standardized methodology developed by the author, sleep-modulatory characteristics of some substances are compared and evaluated in quantitative terms. The sleep regulatory mechanisms, which are composed of complex neurohumoral subsystems, are analyzed from the results of recent neurophysiological and neuroendocrinological experiments. Furthermore, an evolutionary aspect of sleep substances is taken into consideration. Chapters Highlight: Techniques for isolation and evaluation Prostaglandins Paradoxical sleep factors Sleep-promoting substances and nucleosides

Fundamentals of Sleep Technology

Fundamentals of Sleep Technology
Author: Teofilo Lee-Chiong, M.D.
Publisher: Lippincott Williams & Wilkins
Total Pages: 681
Release: 2012-06-01
Genre: Medical
ISBN: 1451132034

Fundamentals of Sleep Technology provides a thorough understanding of the use of polysomnography and other technologies in the evaluation and management of sleep disorders. Coverage includes in-depth reviews of the neurophysiology and cardiopulmonary aspects of sleep, along with the pathophysiology of sleep disorders. Detailed sections on polysomnography include recording procedures, identifying and scoring sleep stages and sleep-related events, and report generation. Chapters discuss therapeutic interventions including positive airway pressure, supplemental oxygen, surgical and pharmacologic treatments, and patient education. A section focuses on pediatric sleep disorders and polysomnography. Also included are chapters on establishing and managing a sleep center and accrediting a sleep program. Fundamentals of Sleep Technology is endorsed by American Association of Sleep Technologists (AAST). AAST committees oversaw the development of this book, defining the table of contents, recruiting the Editors, and providing most of the contributors.

Circadian Rhythm Sleep-Wake Disorders

Circadian Rhythm Sleep-Wake Disorders
Author: R. Robert Auger
Publisher: Springer Nature
Total Pages: 251
Release: 2020-05-26
Genre: Medical
ISBN: 3030438031

This book resolves to bridge the communication gap between research and clinical practice for circadian rhythm sleep-wake disorders. Beginning with a scientific background on biological timekeeping, opening chapters describe the crucial nature of maintaining delicate temporal organization of physiological and molecular events within the body. Following this are discussions on circadian physiology and methods of circadian assessments. Subsequent chapters then relay comprehensive information regarding the International Classification of Sleep Disorders-defined circadian rhythm sleep-wake disorders (CRSWDs), specifically discussing etiology and epidemiology, but focusing on evidence-based treatment data. Concluding discussions provide guidance for the application of light therapy and discuss future roles for optimized lighting environments. Nuanced and market-demanded, Circadian Rhythm Sleep-Wake Disorders: An Evidence-Based Guide for Clinicians and Investigators is an invaluable resource for Sleep Medicine clinicians, circadian researchers, and other interested parties.

Sleep and Mental Illness

Sleep and Mental Illness
Author: S. R. Pandi-Perumal
Publisher: Cambridge University Press
Total Pages: 451
Release: 2010-04-01
Genre: Medical
ISBN: 1139483706

The diagnosis of mental illness is frequently accompanied by sleep problems; conversely, people experiencing sleep problems may subsequently develop mental illness. Sleep and Mental Illness looks at this close correlation and considers the implications of research findings that have emerged in the last few years. Additionally, it surveys the essential concepts and practical tools required to deal with sleep and co-morbid psychiatric problems. The volume is divided into three main sections: basic science, neuroendocrinology, and clinical science. Included are over 30 chapters on topics such as neuropharmacology, insomnia, depression, dementia, autism, and schizophrenia. Relevant questionnaires for the assessment of sleep disorders, including quality-of-life measurement tools, are provided. There is also a summary table of drugs for treating sleep disorders. This interdisciplinary text will be of interest to clinicians working in psychiatry, behavioral sleep medicine, neurology, pulmonary and critical care medicine.

Anesthetic Pharmacology

Anesthetic Pharmacology
Author: Alex S. Evers
Publisher: Cambridge University Press
Total Pages: 2902
Release: 2011-03-10
Genre: Medical
ISBN: 1139497022

In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Sleep and Health

Sleep and Health
Author: Michael A. Grandner
Publisher: Academic Press
Total Pages: 534
Release: 2019-04-17
Genre: Science
ISBN: 0128153741

Sleep and Health provides an accessible yet comprehensive overview of the relationship between sleep and health at the individual, community and population levels, as well as a discussion of the implications for public health, public policy and interventions. Based on a firm foundation in many areas of sleep health research, this text further provides introductions to each sub-area of the field and a summary of the current research for each area. This book serves as a resource for those interested in learning about the growing field of sleep health research, including sections on social determinants, cardiovascular disease, cognitive functioning, health behavior theory, smoking, and more. - Highlights the important role of sleep across a wide range of topic areas - Addresses important topics such as sleep disparities, sleep and cardiometabolic disease risk, real-world effects of sleep deprivation, and public policy implications of poor sleep - Contains accessible reviews that point to relevant literature in often-overlooked areas, serving as a helpful guide to all relevant information on this broad topic area