Emergency Management of Thalassaemia

Emergency Management of Thalassaemia
Author: John Porter (Hematologist)
Publisher:
Total Pages:
Release: 2012
Genre:
ISBN: 9789963717002

The multi-organ pathology of the thalassaemias means that the most successful patient treatment programmes involve a number of medical staff, led by paediatricians and haematologists, but including other specialists in a multidisciplinary approach. However, this means that medical professionals not involved in such multidisciplinary groups, including primary care physicians and the staff of Accident and Emergency departments, rarely treat patients with thalassaemia. As a result, their knowledge of how to address acute complications in such patients is extremely limited. This handbook aims to provide a brief evaluation of the situations in which a thalassaemia patient may seek help beyond the specialized environment he/she is used to. The layout of the handbook is intended to enable the medical professional in a busy clinical setting to draw essential information at a glance, supporting rapid, accurate as possible, decisions on how to proceed.

The Obstetric Hematology Manual

The Obstetric Hematology Manual
Author: Sue Pavord
Publisher: Cambridge University Press
Total Pages: 362
Release: 2018-02-08
Genre: Medical
ISBN: 1108548377

Understand the rapidly growing complexities of obstetric hematology and high-risk pregnancy management, with experts in the field. Now in its second edition, this comprehensive and essential guide focuses on providing the best support for patients and clinical staff, to prevent serious complications in pregnancy and the post-partum period for both mother and baby. Wide-ranging and detailed, the guide offers discussions on basic principles of best care, through to tackling lesser-known hematological conditions, such as cytopenias and hemoglobinopathies. Updated with color illustrations, cutting-edge research, accurate blood film reproductions, and practical case studies, the revised edition places invaluable advice into everyday context. This unique resource is essential reading for trainees and practitioners in obstetrics, anesthesia, and hematology, as well as midwives, nurses, and laboratory staff. Clarifying difficult procedures for disease prevention, the guide ensures safety when the stakes are high. Reflecting current evidence-based guidelines, the updated volume is key to improving pregnancy outcomes worldwide.

Iron Chelation Therapy

Iron Chelation Therapy
Author: Chaim Hershko
Publisher: Springer Science & Business Media
Total Pages: 275
Release: 2012-12-06
Genre: Science
ISBN: 1461505933

Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In these diseases, iron chelating therapy is the only method available for preventing early death caused mainly by myocardial and hepatic iron toxicity. Iron chelating therapy has changed the quality of life and life expectancy of thalassemic patients. However, the high cost and rigorous requirements of deferoxamine therapy, and the significant toxicity of deferiprone underline the need for the continued development of new and improved orally effective iron chelators. Such development, and the evolution of improved strategies of iron chelating therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant develop ments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload (Chapters 1-5).

Strange and Schafermeyer's Pediatric Emergency Medicine, Fifth Edition

Strange and Schafermeyer's Pediatric Emergency Medicine, Fifth Edition
Author: Robert W. Schafermeyer
Publisher: McGraw Hill Professional
Total Pages: 971
Release: 2018-09-22
Genre: Medical
ISBN: 1259860760

Concise, current, need-to-know coverage of emergency medicine in children – presented in full colorEndorsed by the American College of Emergency Physicians "...a comprehensive and current resource for anyone who cares for children in an acute setting, from the office to the emergency department. Its presentation is straightforward, and the information is easy to read and assimilate. It will be a valuable resource for those in the field of pediatric emergency medicine as well as other practitioners who occasionally care for sick children."—JAMA (reviewing an earlier edition)This clinically-focused guide covers the entire field of pediatric emergency medicine. Featuring a strong focus on practical need-to-know information Pediatric Emergency Medicine, Fifth Edition is bolstered by numerous full-color images, bulleted High-Yield Facts at the beginning of each chapter, nearly 100 diagnostic and treatment algorithms, and treatment tables with drug dosages. Endorsed by the American College of Emergency Physicians, this book is perfect for use in the emergency department or the pediatric clinic.FEATURES•Chapters open with bulleted High-Yield Facts, followed by just enough pathophysiology for understanding, and continue with a focus on what needs to be done to protect and save the child•Broad scope spans the full spectrum of pediatric emergencies -- from trauma care to psychosocial emergencies•NEW CHAPTER on Brief Resolved Unexplained Events (BRUE)•Opens with an important symptom-based section of Cardinal Presentations that familiarizes you with crucial life-saving protocols•Covers all major categories of disease that present in children on an urgent or emergent basisIf you are in need of a very readable and easily accessible, evidence-based text written to help you provide high quality emergency medical care to children, your search ends here.

Thalassemia and Other Hemolytic Anemias

Thalassemia and Other Hemolytic Anemias
Author: Isam Jaber Al-Zwaini
Publisher: BoD – Books on Demand
Total Pages: 140
Release: 2018-07-11
Genre: Medical
ISBN: 1789233666

Thalassemia is a very common disease first described by pediatrician Thomas Benton Cooley in 1925 who described it in a patient of Italian origin. At that time, it was designated as Cooley's anemia. George Hoyt Whipple, a Nobel prize winner, and W. L. Bradford, a professor of pediatrics at the University of Rochester, coined the term thalassemia in 1936, which in Greek means anemia of the sea (Thalassa means "sea", and emia means "blood"), due to the fact that it is very common in the area of the Mediterranean Sea. This name is actually misleading because it can occur everywhere in the world. Thalassemia is not a single disease; it is rather a group of hereditary disorders of the production of globulin chain of the hemoglobin. Throughout the world, thalassemia affects approximately 4.4 of every 10,000 live births. It represents a major social and emotional impact on the patient and his family and a major burden on health services where the prevalence is high.

Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies

Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies
Author: Stephan Lobitz
Publisher: MDPI
Total Pages: 160
Release: 2019-10-07
Genre: Medical
ISBN: 3039216147

Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies is a Special Issue of the International Journal of Neonatal Screening. Sickle cell disease is one of the most common inherited blood disorders, with a huge impact on health care systems due to high morbidity and high mortality associated with the undiagnosed disease. Newborn screening helps to make the diagnosis early and to prevent fatal complications and diagnostic odysseys. This book gives an overview of diagnostic standards in newborn screening for sickle cell disease and examples of existing newborn screening programs.

Basics of Blood Management

Basics of Blood Management
Author: Petra Seeber
Publisher: John Wiley & Sons
Total Pages: 554
Release: 2012-06-21
Genre: Medical
ISBN: 111833809X

To reduce transfusion-related morbidity and mortality, it is recommended that an integrated approach to blood management is employed using all available tools to reduce a patient's exposure to donor blood. Meeting the need for a book covering the concepts of blood management as a trend towards multidisciplinary blood management, this new edition is an important resource, providing healthcare professionals with a tool to develop background knowledge in blood management, its organization, methods and tools. Practicing clinicians will be fully prepared to successfully start and run blood management programs.

Obstetric and Intrapartum Emergencies

Obstetric and Intrapartum Emergencies
Author: Edwin Chandraharan
Publisher: Cambridge University Press
Total Pages: 353
Release: 2021-06-03
Genre: Medical
ISBN: 1108847382

Global and national confidential inquiry reports show that 60 to 80% of maternal and neonatal morbidity and mortality are due to avoidable errors. This comprehensive and illustrated second edition offers a practical guide to the management of obstetric, medical, surgical, anaesthetic and newborn emergencies in addition to organisational and training issues. The book is divided conveniently into nine sections and updated throughout in line with modern research and practice. Several new chapters cover setting up skills and drills training in maternity services to reduce avoidable harm, managing obstetric emergencies during 'home births' and in low-risk midwifery units, and minimizing maternal and fetal morbidity in failed operative vaginal delivery. Each chapter includes a practical algorithm for quick reference, the scientific basis for proposed actions, a case-based practical exercise and useful learning tools such as 'Key Pearls' and 'Key Pitfalls'. An invaluable resource for obstetricians, neonatologists, midwives, medical students, anesthesiologists and the wider perinatal team.