Robotics for Cell Manipulation and Characterization

Robotics for Cell Manipulation and Characterization
Author: Changsheng Dai
Publisher: Elsevier
Total Pages: 402
Release: 2023-04-20
Genre: Computers
ISBN: 0323952143

Robotics for Cell Manipulation and Characterization provides fundamental principles underpinning robotic cell manipulation and characterization, state-of-the-art technical advances in micro/nano robotics, new discoveries of cell biology enabled by robotic systems, and their applications in clinical diagnosis and treatment. This book covers several areas, including robotics, control, computer vision, biomedical engineering and life sciences using understandable figures and tables to enhance readers' comprehension and pinpoint challenges and opportunities for biological and biomedical research. - Focuses on, and comprehensively covers, robotics for cell manipulation and characterization - Highlights recent advances in cell biology and disease treatment enabled by robotic cell manipulation and characterization - Provides insightful outlooks on future challenges and opportunities

Microdevices and Microsystems for Cell Manipulation

Microdevices and Microsystems for Cell Manipulation
Author: Aaron T. Ohta
Publisher: MDPI
Total Pages: 179
Release: 2018-07-03
Genre: Science
ISBN: 3038426180

This book is a printed edition of the Special Issue "Microdevices and Microsystems for Cell Manipulation" that was published in Micromachines

3D Electro-Rotation of Single Cells

3D Electro-Rotation of Single Cells
Author: Liang Huang
Publisher: Springer Nature
Total Pages: 101
Release: 2022-05-31
Genre: Technology & Engineering
ISBN: 3031016661

Dielectrophoresis microfluidic chips have been widely used in various biological applications due to their advantages of convenient operation, high throughput, and low cost. However, most of the DEP microfluidic chips are based on 2D planar electrodes which have some limitations, such as electric field attenuation, small effective working regions, and weak DEP forces. In order to overcome the limitations of 2D planar electrodes, two kinds of thick-electrode DEP chips were designed to realize manipulation and multi-parameter measurement of single cells. Based on the multi-electrode structure of thick-electrode DEP, a single-cell 3D electro-rotation chip of "Armillary Sphere" was designed. The chip uses four thick electrodes and a bottom planar electrode to form an electric field chamber, which can control 3D rotation of single cells under different electric signal configurations. Electrical property measurement and 3D image reconstruction of single cells are achieved based on single-cell 3D rotation. This work overcomes the limitations of 2D planar electrodes and effectively solves the problem of unstable spatial position of single-cell samples, and provides a new platform for single-cell analysis. Based on multi-electrode structure of thick-electrode DEP, a microfluidic chip with optoelectronic integration was presented. A dual-fiber optical stretcher embedded in thick electrodes can trap and stretch a single cell while the thick electrodes are used for single-cell rotation. Stretching and rotation manipulation gives the chip the ability to simultaneously measure mechanical and electrical properties of single cells, providing a versatile platform for single-cell analysis, further extending the application of thick-electrode DEP in biological manipulation and analysis.

Micro-Nanorobotic Manipulation Systems and Their Applications

Micro-Nanorobotic Manipulation Systems and Their Applications
Author: Toshio Fukuda
Publisher: Springer Science & Business Media
Total Pages: 347
Release: 2013-02-28
Genre: Technology & Engineering
ISBN: 3642363911

Micro/Nano Robotics and Automation technologies have rapidly grown associated with the growth of Micro and Nanotechnologies. This book presents a summary of fundamentals in micro-nano scale engineering and the current state of the art of these technologies. “Micro-Nanorobotic Manipulation Systems and their Applications” introduces these advanced technologies from the basics and applications aspects of Micro/Nano-Robotics and Automation from the prospective micro/nano-scale manipulation. The book is organized in 9 chapters including an overview chapter of Micro/Nanorobotics and Automation technology from the historical view and important related research works. Further chapters are devoted to the physics of micro-nano fields as well as to material and science, microscopes, fabrication technology, importance of biological cell, and control techniques. Furthermore important examples, applications and a concise summary of Micro-Nanorobotics and Automation technologies are given.

Biosensors for Single-Cell Analysis

Biosensors for Single-Cell Analysis
Author: Jian Chen
Publisher: Academic Press
Total Pages: 184
Release: 2021-10-26
Genre: Science
ISBN: 0323885594

Biosensors for Single-Cell Analysis explores a wide range of biosensor technologies and their applications in single-cell characterization and analysis. Sections cover key biophysical and chemical single-cell properties that consider proteomic, metabolic, electrical, mechanical and optical properties. Each chapter features key definitions and case studies, providing detailed guidance for researchers who want to replicate covered solutions in their work. Tutorial sections, evaluations of the current state-of-the-field and future developments are also included. Microfluidic approaches to characterization, such as microfluidic impedance flow cytometry and microfluidic flow cytometry are considered alongside more conventional approaches, such as mass spectroscopy, fluorescent and mass flow cytometry. Additionally, key types of biosensors are covered, including atomic force microscopy, micropipette aspiration, optical tweezers, microfluidic hydrodynamic stretchers, microfluidic constriction channel and microfluidic optical stretchers. - Includes chapters focused on key single-cell properties, such as proteomic, metabolic and mechanical characterization - Features case studies that illustrate the application of biosensors for single-cell analysis - Considers microfluidic approaches for each single-cell property discussed - Explores future directions for single-cell analysis and biosensor technology

Interdisciplinary Mechatronics

Interdisciplinary Mechatronics
Author: M. K. Habib
Publisher: John Wiley & Sons
Total Pages: 422
Release: 2013-05-06
Genre: Technology & Engineering
ISBN: 1118577078

Mechatronics represents a unifying interdisciplinary and intelligent engineering science paradigm that features an interdisciplinary knowledge area and interactions in terms of the ways of work and thinking, practical experiences, and theoretical knowledge. Mechatronics successfully fuses (but is not limited to) mechanics, electrical, electronics, informatics and intelligent systems, intelligent control systems and advanced modeling, intelligent and autonomous robotic systems, optics, smart materials, actuators and biomedical and biomechanics, energy and sustainable development, systems engineering, artificial intelligence, intelligent computer control, computational intelligence, precision engineering and virtual modeling into a unified framework that enhances the design of products and manufacturing processes. Interdisciplinary Mechatronics concerns mastering a multitude of disciplines, technologies, and their interaction, whereas the science of mechatronics concerns the invention and development of new theories, models, concepts and tools in response to new needs evolving from interacting scientific disciplines. The book includes two sections, the first section includes chapters introducing research advances in mechatronics engineering, and the second section includes chapters that reflects the teaching approaches (theoretical, projects, and laboratories) and curriculum development for under- and postgraduate studies. Mechatronics engineering education focuses on producing engineers who can work in a high-technology environment, emphasize real-world hands-on experience, and engage in challenging problems and complex tasks with initiative, innovation and enthusiasm. Contents: 1. Interdisciplinary Mechatronics Engineering Science and the Evolution of Human Friendly and Adaptive Mechatronics, Maki K. Habib. 2. Micro-Nanomechatronics for Biological Cell Analysis and Assembly, Toshio Fukuda, Masahiro Nakajima, Masaru Takeuchi, Tao Yue and Hirotaka Tajima. 3. Biologically Inspired CPG-Based Locomotion Control System of a Biped Robot Using Nonlinear Oscillators with Phase Resetting, Shinya Aoi. 4. Modeling a Human’s Learning Processes toward Continuous Learning Support System, Tomohiro Yamaguchi, Kouki Takemori and Keiki Takadama. 5. PWM Waveform Generation Using Pulse-Type Hardware Neural Networks, Ken Saito, Minami Takato, Yoshifumi Sekine and Fumio Uchikoba. 6. Parallel Wrists: Limb Types, Singularities and New Perspectives, Raffaele Di Gregorio. 7. A Robot-Assisted Rehabilitation System – RehabRoby, Duygun Erol Barkana and Fatih Özkul. 8. MIMO Actuator Force Control of a Parallel Robot for Ankle Rehabilitation, Andrew Mcdaid, Yun Ho Tsoi and Shengquan Xie. 9. Performance Evaluation of a Probe Climber for Maintaining Wire Rope, Akihisa Tabata, Emiko Hara and Yoshio Aoki. 10. Fundamentals on the Use of Shape Memory Alloys in Soft Robotics, Matteo Cianchetti. 11. Tuned Modified Transpose Jacobian Control of Robotic Systems, S. A. A. Moosavian and M. Karimi. 12. Derivative-Free Nonlinear Kalman Filtering for PMSG Sensorless Control, Gerasimos Rigatos, Pierluigi Siano and Nikolaos Zervos. 13. Construction and Control of Parallel Robots, Moharam Habibnejad Korayem, Soleiman Manteghi and Hami Tourajizadeh. 14. A Localization System for Mobile Robot Using Scanning Laser and Ultrasonic Measurement, Kai Liu, Hongbo Li and Zengqi Sun. 15. Building of Open-Structure Wheel-Based Mobile Robotic Platform, Aleksandar Rodic and Ivan Stojkovic. 16. Design and Physical Implementation of Holonomous Mobile Robot–Holbos, Jasmin Velagic, Admir Kaknjo, Faruk Dautovic, Muhidin Hujdur and Nedim Osmic. 17. Advanced Artificial Vision and Mobile Devices for New Applications in Learning, Entertainment and Cultural Heritage Domains, Gian Luca Foresti, Niki Martinel, Christian Micheloni and Marco Vernier. 18. Application of Stereo Vision and ARM Processor for Motion Control, Moharam Habibnejad Korayem, Michal Irani and Saeed Rafee Nekoo. 19. Mechatronics as Science and Engineering – or Both, Balan Pillai and Vesa Salminen. 20. A Mechatronic Platform for Robotic Educational Activities, Ioannis Kostavelis, Evangelos Boukas, Lazaros Nalpantidis and Antonios Gasteratos. 21. The Importance of Practical Activities in the Formation of Mechatronic Engineers, Joao Carlos M. Carvalho and Vera Lúcia D.S. Franco About the Authors Maki K. Habib is Professor of Robotics and Mechatronics in the School of Science and Engineering, at the American University in Cairo, Egypt. He has been regional editor (Africa/Middle East,) for the International Journal of Mechatronics and Manufacturing Systems (IJMMS) since 2010. He is the recipient of academic awards and has published many articles and books. J. Paulo Davim is Aggregate Professor in the Department of Mechanical Engineering at the University of Aveiro, Portugal and is Head of MACTRIB (Machining and Tribology Research Group). His main research interests include manufacturing, materials and mechanical engineering.

Handbook of Nanophysics

Handbook of Nanophysics
Author: Klaus D. Sattler
Publisher: CRC Press
Total Pages: 888
Release: 2010-09-17
Genre: Science
ISBN: 1420075497

The tools of nanodiagnostics, nanotherapy, and nanorobotics are expected to revolutionize the future of medicine, leading to presymptomatic diagnosis of disease, highly effective targeted treatment therapy, and minimum side effects. Handbook of Nanophysics: Nanomedicine and Nanorobotics presents an up-to-date overview of the application of nan

Aquaporins

Aquaporins
Author: Baoxue Yang
Publisher: Springer
Total Pages: 283
Release: 2017-03-03
Genre: Medical
ISBN: 9402410570

This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. By focusing on the advances made over the last 20 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in order to stimulate further research in new directions.

Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms

Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms
Author: Xinyu Liu
Publisher: Academic Press
Total Pages: 406
Release: 2021-08-14
Genre: Science
ISBN: 0128242434

Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms provides a comprehensive introduction to the state-of-the-art micro and nano systems that have recently been developed and applied to biophysical studies of cells and small organisms. These micro and nano systems span from microelectromechanical systems (MEMS) and microfluidic devices to robotic micro-nanomanipulation systems. These biophysical studies range from cell mechanics to the neural science of worms and Drosophila. This book will help readers understand the fundamentals surrounding the development of these tools and teach them the most recent advances in cellular and organismal biophysics enabled by these technologies. - Comprehensive coverage of micro and nano-system technology and application to biophysical studies of cells and small organisms. - Highlights the most recent advances in cellular and organismal biophysics enabled by micro and nano systems. - Insightful outlook on future directions and trends in each chapter covering a sub-area of the book topic.