Editor’s Pick 2021: Highlights in Cell Adhesion and Migration
Author | : Claudia Tanja Mierke |
Publisher | : Frontiers Media SA |
Total Pages | : 233 |
Release | : 2022-03-30 |
Genre | : Science |
ISBN | : 2889747824 |
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Author | : Claudia Tanja Mierke |
Publisher | : Frontiers Media SA |
Total Pages | : 233 |
Release | : 2022-03-30 |
Genre | : Science |
ISBN | : 2889747824 |
Author | : Ana Cuenda |
Publisher | : Frontiers Media SA |
Total Pages | : 166 |
Release | : 2022-02-07 |
Genre | : Science |
ISBN | : 2889743470 |
Author | : Craig Michael Walsh |
Publisher | : Frontiers Media SA |
Total Pages | : 188 |
Release | : 2022-03-04 |
Genre | : Science |
ISBN | : 2889745759 |
Author | : Philipp Kaldis |
Publisher | : Frontiers Media SA |
Total Pages | : 190 |
Release | : 2022-08-22 |
Genre | : Science |
ISBN | : 2889768058 |
Author | : Atsushi Asakura |
Publisher | : Frontiers Media SA |
Total Pages | : 167 |
Release | : 2022-04-21 |
Genre | : Science |
ISBN | : 288974941X |
Author | : Ramani Ramchandran |
Publisher | : Frontiers Media SA |
Total Pages | : 158 |
Release | : 2022-02-17 |
Genre | : Science |
ISBN | : 2889744124 |
Author | : Terri Grodzicker |
Publisher | : |
Total Pages | : 0 |
Release | : 2011 |
Genre | : Cell nuclei |
ISBN | : 9781936113071 |
This volume is based on presentations by the world-renowned investigators who gathered at the 75th annual Cold Spring Harbor Symposium on Quantitative Biology to discuss the organization and function of the cell nucleus. It reviews the latest advances in research into nuclear structure, the organization of the genome within the nucleus, and spatiotemporal coordination of nuclear processes. The topics examined include nuclear domains, chromatin organization, transcription and RNA processing, DNA replication, nuclear reprogramming, and epigenetics. Cancer, premature aging syndromes, and other diseases that may be associated with altered nuclear organization are also covered.
Author | : Kristian M. Hargadon |
Publisher | : Humana |
Total Pages | : 674 |
Release | : 2022-03-26 |
Genre | : Medical |
ISBN | : 9781071612071 |
This extensive book brings together leading melanoma researchers from across the world and highlights many of the cutting-edge protocols and experimental systems currently being used to investigate questions surrounding this disease. The volume opens with sections on 2D and 3D cell culture-based approaches for studying melanoma biology, and continues with collections of chapters examining various approaches for detecting, isolating, and characterizing circulating melanoma cells, circulating tumor DNA, and exosomes, as well as experimental procedures for studying and detecting melanoma metastasis in both pre-clinical and clinical settings, bioinformatics-based approaches, protocols for quantifying and characterizing immune cell infiltrates in both melanoma tumors and tertiary lymphoid structures, and development and evaluation of therapeutic strategies for melanoma treatment. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and comprehensive, Melanoma: Methods and Protocols aims to serve basic research scientists and clinicians who bring questions from the clinic into the lab in order to translate observations in the laboratory into improved patient care for this highly malignant form of cancer. Chapter 14 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author | : Rahul Jandial |
Publisher | : CRC Press |
Total Pages | : 312 |
Release | : 2013-08-08 |
Genre | : Medical |
ISBN | : 9781587066597 |
Most cancer deaths are a result of metastasis. The spread of a primary tumor to colonize neighboring and distant organs is the relentless endgame that defines the neoplastic process. Patients who have been diagnosed with cancer are treated to prevent both the recurrence of the tumor at the site of origin and metastasis that would re-stage them as advanced stage IV cancer. Historically and still with some types of cancer, stage IV is perceived by patients as “terminal.” Fortunately, recent molecular therapies have extended the lives of patients with advanced cancer and reassuringly people living with metastatic disease increasingly visit our clinics. What is the path forward? Given that the consilience of science and medicine is a dynamic art from which therapies arise, it would be misguided to consider any single work adequate at capturing the horizon for research. So with humility we constructed this text as primer for scientists. It begins with a broad introduction to the clinical management of common cancers. This is intended to serve as a foundation for investigators to consider when developing basic science hypotheses. Unquestionably, medical and surgical care of cancer patients reveals biology and dictates how novel therapeutics will ultimately be evaluated in clinical trials. The second section of this text offers provocative and evolving insights that underscore the breadth of science involved in the elucidation of cancer metastasis biology. The text concludes with information that integrates scientific and clinical foundations to highlight translational research. This book serves as a framework for scientists to conceptualize clinical and translational knowledge on the complexity of disease that is metastatic cancer.