Dynamics of Degeneration and Growth in Neurons

Dynamics of Degeneration and Growth in Neurons
Author: Kjell Fuxe
Publisher: Elsevier
Total Pages: 617
Release: 2013-10-22
Genre: Nature
ISBN: 1483146472

Dynamics of Degeneration and Growth in Neurons is a collection of papers presented at the International Symposium on the Dynamics of Degeneration and Growth in Neurons, held in Stockholm, Sweden, on May 16-18, 1973. Contributors explore the dynamics of degeneration and growth of central and peripheral neurons, touching on a wide range of topics such as the neurotoxic action of 6-hydroxy-dopa on central catecholamine neurons; axonal transport of proteins in growing and regenerating neurons; and collateral reinnervation in the central nervous system. Comprised of 50 chapters, this volume begins with an overview of degeneration processes in central and peripheral neurons. Results of microfluorimetric and neurochemical studies on degenerating and regenerating adrenergic nerves are presented. The next section is devoted to axoplasmic transport as a mechanism for axonal support and growth and includes chapters dealing with the effects of degeneration and axoplasmic transport blockade on synaptic ultrastructure, function, and protein composition; the role of axoplasmic flow in trophism of skeletal muscle; and proximodistal transport of acetylcholine in peripheral cholinergic neurons. The remaining chapters discuss the nerve growth factor receptor and its specific binding in sympathetic ganglia; the noradrenergic innervation of cerebellar Purkinje cells; and the possible role of brain and peripheral monoamines in the ontogenesis of normal and drug-induced responses in the immature mammal. This book will be of interest to physiologists and neurologists.

Degeneration and Regeneration in the Nervous System

Degeneration and Regeneration in the Nervous System
Author: Norman Saunders
Publisher: CRC Press
Total Pages: 354
Release: 2003-09-02
Genre: Medical
ISBN: 0203304489

Degeneration and Regeneration in the Nervous System brings together an international team of contributors to produce a series of critical reviews appraising key papers in the field. The pace of research on brain and spinal cord injury quickened considerably in the last ten years and there is much that is new and important that is covered in this book. However, there is still a long way to go before our knowledge will explain fully why the central nervous system has such a limited capacity for regeneration, and before experimental solutions can be applied to the patient. With emphasis on actual and therapeutic importance of the work reviewed, Degeneration and Regeneration in the Nervous System is a useful overview for graduate students, their teachers and researchers working in this field.

The Axon

The Axon
Author: Stephen G. Waxman
Publisher:
Total Pages: 710
Release: 1995
Genre: Axons
ISBN: 0195082931

The axon, interposed between the cell body and the synaptic terminals in most neurons, plays a crucial role in connecting neurons and acting as a conduit for the transmission of information between them. This book provides a comprehensive and up-to-date compendium that brings together chapterson the structure, function, and pathophysiology of axons in both the PNS and CNS. Carefully written, well-illustrated with superb illustrations, and generously referenced, the 33 chapters and introduction have been authored by 49 world-renowned authorities. Recent advances in the molecularneurobiology of axons are carefully reviewed, and new areas, such as the molecular biology of ion channels and myelination, the role of calcium in pathophysiology and regeneration, cell adhesion molecules and their roles in axo-glial interactions and axonal guidance, and optical recording methods,are highlighted. This book will provide an essential reference for neuroscientists as well as clinicians such as neurologists, neurosurgeons, and clinical electrophysiologists interested in axons.

Axon Degeneration

Axon Degeneration
Author: Elisabetta Babetto
Publisher: Humana
Total Pages: 0
Release: 2020-06-11
Genre: Science
ISBN: 9781071605844

This book is a collection of classical as well as innovative methods used to investigate axon degeneration with a particular focus on addressing the common challenges encountered while performing these procedures. Particular attention is devoted to the study of axon loss in several model organisms, as each poses unique challenges and provides powerful advantages. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Axon Degeneration: Methods and Protocols is an ideal guide for facilitating the application and further development of these protocols, which will help the scientific community tackle important questions regarding axon degeneration. Chapters 2, 3, and 20 are available Open Access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Developmental Health and the Wealth of Nations

Developmental Health and the Wealth of Nations
Author: Daniel P. Keating
Publisher: Guilford Press
Total Pages: 428
Release: 2000-02-08
Genre: Psychology
ISBN: 9781572304550

Probing the effects of the social environment upon human development, this volume asks how we can best support the health and well-being of infants and children in an era of rapid economic and technological change. The book presents cogent findings on human development as both an individual and a population phenomenon. Topics covered include links between socioeconomic status, achievement, and health; the impact of early experience upon brain and behavioral development; and how schools and communities can develop new kinds of learning environments to enhance adaptation and foster intellectual growth. Synthesizing developmental, biological, and social perspectives, this volume will appeal to a broad interdisciplinary audience.

Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury
Author: Daniel Laskowitz
Publisher: CRC Press
Total Pages: 388
Release: 2016-04-21
Genre: Medical
ISBN: 1498766579

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

The Neural Crest

The Neural Crest
Author: Nicole Le Douarin
Publisher: Cambridge University Press
Total Pages: 494
Release: 1999-11-28
Genre: Medical
ISBN: 9780521620109

This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.

Neuroproteomics

Neuroproteomics
Author: Oscar Alzate
Publisher: CRC Press
Total Pages: 356
Release: 2009-10-26
Genre: Medical
ISBN: 1420076264

In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg

Molecular Neurology

Molecular Neurology
Author: Stephen Waxman
Publisher: Elsevier
Total Pages: 597
Release: 2010-07-26
Genre: Medical
ISBN: 0080546188

Why a book on molecular neurology? Molecular neuroscience is advancing at a spectacular rate. As it does so, it is revealing important clues to the pathogenesis and pathophysiology of neurological diseases, and to the therapeutic targets that they present. Medicines work by targeting molecules. The more specific the targeting, the more specific the actions, and the fewer the side effects. Molecular Neurology highlights, for graduate and MD-PhD students, research fellows and research-oriented clinical fellows, and researchers in the neurosciences and other biomedical sciences, the principles underlying molecular medicine as related to neurology. Written by internationally recognized experts, this well-illustrated and well-referenced book presents the most up-to-date principles and disease examples relevant to molecular neurology, and reviews the concepts, strategies, and latest progress in this field. This book will interest anyone studying the molecular basis of neurology, or developing new therapies in neurology. - Describes the newest molecular aspects of neurological disorders - Provides an introduction to neurological disorders for basic scientists - Updates clinicians and clinical researchers on the most recent developments