NCHRP Report 566 is designed to help facilitate the use of supplementary cementitious materials to enhance durability of concrete used in highway construction, especially bridge decks. The report includes a methodology for selecting optimum concrete mixture proportions that focuses on durability aspects of concrete and the performance requirements for specific environmental conditions. The methodology is presented in a text format and as a computational tool, in the form of a Visual Basic?driven Microsoft Excel spreadsheet. Background information and a hypothetical case study was published as NCHRP Web-Only Document 110: Supplementary Cementitious Materials to Enhance Durability of Concrete Bridge Decks. The Statistical Experimental Design for Optimizing Concrete (SEDOC), the computational tool for the concrete mixture optimization methodology, and the user?s guide are available in a ZIP format for download.