Rational Therapeutics for Infants and Children

Rational Therapeutics for Infants and Children
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 135
Release: 2000-04-07
Genre: Medical
ISBN: 0309183642

The Institute of Medicine's (IOM's) Roundtable on Research and Development of Drugs, Biologics, and Medical Devices evolved from the Forum on Drug Development, which was established in 1986. Sponsor representatives and IOM determined the importance of maintaining a neutral setting for discussions regarding long-term and politically sensitive issues justified the need to revise and enhance past efforts. The new Roundtable is intended to be a mechanism by which a broad group of experts from the public* and private sectors can be convened to conduct a dialogue and exchange information related to the development of drugs, biologics, and medical devices. Members have expertise in clinical medicine, pediatrics, clinical pharmacology, health policy, health insurance, industrial management, and product development; and they represent interests that address all facets of public policy issues. From time to time, the Roundtable requests that a workshop be conducted for the purpose of exploring a specific topic in detail and obtaining the views of additional experts. The first workshop for the Roundtable was held on April 14 and 15, 1998, and was entitled Assuring Data Quality and Validity in Clinical Trials for Regulatory Decision Making. The summary on that workshop is available from IOM. This workshop summary covers the second workshop, which was held on May 24 and 25, 1999, and which was aimed at facilitating the development and proper use of drugs, biologics, and medical devices for infants and children. It explores the scientific underpinnings and clinical needs, as well as the regulatory, legal, and ethical issues, raised by this area of research and development.

Safe and Effective Medicines for Children

Safe and Effective Medicines for Children
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 432
Release: 2012-10-13
Genre: Medical
ISBN: 0309225493

The Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) were designed to encourage more pediatric studies of drugs used for children. The FDA asked the IOM to review aspects of pediatric studies and changes in product labeling that resulted from BPCA and PREA and their predecessor policies, as well as assess the incentives for pediatric studies of biologics and the extent to which biologics have been studied in children. The IOM committee concludes that these policies have helped provide clinicians who care for children with better information about the efficacy, safety, and appropriate prescribing of drugs. The IOM suggests that more can be done to increase knowledge about drugs used by children and thereby improve the clinical care, health, and well-being of the nation's children.

Neonatal and Pediatric Pharmacology

Neonatal and Pediatric Pharmacology
Author: Sumner J. Yaffe
Publisher: Lippincott Williams & Wilkins
Total Pages: 1072
Release: 2011
Genre: Medical
ISBN: 0781795389

"Neonatal and Pediatric Pharmacology offers guidelines for safe, effective, and rational drug therapy in newborns, children and adolescents. The book provides relevant and useful data on the molecular, physiologic, biochemical, and pharmacologic mechanisms of drug action and therapy in this population. The authors identify areas of innovative basic and translational research necessary for the continuing evaluation and development of drugs for the fetus, newborns, children and adolescents. Neonatal and Pediatric Pharmacology is is a valuable reference for all health care professionals who treat the fetus, newborns, children, and adolescents, including neonatologists, nurses, pediatricians, general practitioners, students, obstetricians, perinatologists, surgeons and allied health professionals. It will be useful anytime during the day and especially in the middle of the night when knowledge of appropriate indications, safe and effective use, dosage, and therapeutic regimen for a certain drug or molecular entity is immediately needed. The book is also directed to those involved in basic, clinical, and other academic pharmacological research, the pharmaceutical industry, and regulatory agencies dealing with drug and therapeutic developments for this population. Those teaching pharmacology and therapeutics will find this compilation of information extremely useful in preparing teaching materials"--Provided by publisher.

Yaffe and Aranda's Neonatal and Pediatric Pharmacology

Yaffe and Aranda's Neonatal and Pediatric Pharmacology
Author: Jacob V. Aranda
Publisher: Lippincott Williams & Wilkins
Total Pages: 2499
Release: 2020-11-05
Genre: Medical
ISBN: 1975112490

The premier comprehensive textbook in the field, Yaffe and Aranda’s Neonatal and Pediatric Pharmacology, Fifth Edition, provides an authoritative overview of all aspects of drug therapy in newborns, children, and adolescents. It offers evidence-based guidelines for safe, effective, and rational drug therapy, including specific recommendations for all major drug classes and diseases. Now in a vibrant two-color format, this fully revised reference is an indispensable resource for pediatricians, neonatologists, pediatric residents, and fellows in different pediatric subspecialties, including neonatal medicine and pediatric critical care.

Comprehensive Neonatal Nursing Care

Comprehensive Neonatal Nursing Care
Author: Carole Kenner, PhD, RN, FAAN, FNAP, ANEF
Publisher: Springer Publishing Company
Total Pages: 1022
Release: 2013-08-21
Genre: Medical
ISBN: 0826109764

"This book provides a complete look at neonatal healthcare delivery. This edition includes discussions of contemporary topics of interest, such as informatics, genetics, global health, and family-centered care, which are vital to providers caring for neonates today. The case studies and the evidence-based practice dialogues at the end of each chapter provide great opportunities for further reflection. The book is useful to a wide audience in nursing, including undergraduate and graduate nursing students, practicing neonatal and pediatric nurses, and advanced practice nurses who care for neonates." Score: 92, 4 Stars.--Doody's Medical Reviews This 'classic' has been thoroughly updated to incorporate the most up-to-date research findings and strategies for providing cost-effective and evidence-based care. New chapters address emerging infections, the late preterm infant, and neonatal care from a global perspective. Included are updated neonatal care protocols and procedures, neuroprotective risk factors, new treatments, and new trends in developmental care. Text integrates the Institute of Medicine's (10M) five competencies, reflects the Affordable Healthcare Act and the Robert Wood Johnson and 10M report "The Future of Nursing." The text continues to provide neonatal care from a physiologic and pathophysiologic approach, with a major emphasis on nursing management at the bedside and advanced practice level. Each neonatal body system is presented, along with E-B interventions to assist in understanding the 'why' behind what is seen in the clinical area. Integrative management is threaded through the text along with extensive research findings to support practice strategies and rationales for sound clinical decision-making. Topics of recent interest include iatrogenic complications, neonatal pain, use of computers or other technology in neonatal care, and neonatal AIDS. Case studies enhance understanding of both common and rare neonatal conditions. New to the Fifth Edition: New chapters: emerging infections, the late preterm infant, and neonatal care from a global perspective Updated neonatal care protocols and procedures, neuroprotective factors, new treatment modalities and new trends in developmental care Tackles the UN Millennium Development Goals (MDGs) Addresses the expansion of the nurse's role in the US and worldwide Provides case studies that lead the reader through the identification, diagnosis, treatment, and evaluation of common and rare neonatal conditions

Handbook of Pediatric Drug Therapy and Immunization

Handbook of Pediatric Drug Therapy and Immunization
Author: KR Suneja
Publisher: Jaypee Brothers Medical Publishers
Total Pages: 545
Release: 2019-08-31
Genre: Medical
ISBN: 9388958594

SECTION 1 DRUG THERAPY 1Guidelines for Antimicrobial Therapy 2Antibiotic Therapy in Neonatal Infections 3 Spectra and Effectiveness of Various Antimicrobial Agents 4Preferred Antimicrobial Agents Against Selected Bacteria 5Antimicrobial Prophylaxis in Patients/Contacts 6Drug Therapy and Prevention in Childhood Tuberculosis 7Malaria - Treatment and Chemoprophylaxis 8Treatment of Helminthic, Protozoal and Other Parasitic Infections 9Drugs for Selected Viral Infections 10Guidelines for HIV Treatment 11Preferred Therapy for Selected Fungal Pathogens 12Fluids, Electrolytes and Acid Base Management in Acute Gastroenteritis 13Treatment of Acute Hyperkalemia and Hypokalemia 14Management of Asthma 15Drug Therapy in Epilepsy and Neonatal Seizures 16Pharmacotherapy in Congestive Heart Failure 17Pharmacotherapy in Hypertension and Hypertensive Emergencies 18Guidelines for Management of Cardiac Arrhythmias 19Pediatric Life Support Algorithms and Emergency Drugs 20Understanding and Management of Shock 21Management of Dengue MILD MODERATE SEVERE 22"Blue Spells" in Tetralogy of Fallot-Management and Prevention 23Management of Childhood Type I Diabetes and Diabetic Ketoacidosis 24Drug Therapy in Anaphylaxis 25Management of Intracranial Hypertension 26Management of Haemophilia 27Blood Component Therapy SECTION 2 IMMUNIZATION 28Immunization 29Immunoprophylaxis Postexposure SECTION 3 POISONING 30Non-Toxic Household Products and Pharmaceuticals 31Antidotes for Common Poisoning 32Medications Whose Single Dose may be Fatal for a Toddler SECTION 4 DRUGS IN PEDIATRICS 33Drugs in Pediatric Use 34Dosage of Antimicrobial Agents in Neonates 35Drugs in Renal Failure

Medications in Pediatrics

Medications in Pediatrics
Author: American Academy of Pediatrics
Publisher:
Total Pages: 500
Release: 2019-12-20
Genre:
ISBN: 9781610024341

This new compendium contains AAP clinical practice guidelines, policy statements, clinical reports, and technical reports related to the use of medications in the pediatric population. It is designed to be a handy reference to AAP policies and recommended best practices. Sections include Pediatric Drug Principles Allergy/Asthma Management Contraception Emergency Care Infections Mental Health Management Substance Use Issues Neonatal Care Pain Management Plus much more...

Chemotherapy in Neonates and Infants

Chemotherapy in Neonates and Infants
Author: Carolina Witchmichen Penteado Schmidt
Publisher: Springer
Total Pages: 210
Release: 2018-04-12
Genre: Medical
ISBN: 3319705911

This book provides a comprehensive overview of pediatric oncology, discussing drug therapy and treatment in children under the age of 1 year. It is the first volume to focus on chemotherapy in newborns and infants, especially the daily clinical practice and treatment protocols. Intended as a practical manual, it addresses all the major topics related to pediatric oncology in an accessible and easy-to-use format. It examines topics in pediatric oncology therapeutics, including drug metabolism, excretion, toxicity, drugs that can be used for each week or month of the patient’s life, dose adjustment and treatment protocols.Chemotherapy in Neonates and Infants focuses on the safe treatment of children in the first year of life, and is aimed at pediatric oncology/hematology institutions, clinics and departments. It is particularly valuable for researchers, pediatric oncology physicians, pediatric and neonatology physicians, oncology pharmacists and the other healthcare professionals directly involved in the chemotherapy of neonates and infants.

Childhood Asthma

Childhood Asthma
Author: Stanley J Szefler
Publisher: CRC Press
Total Pages: 740
Release: 2005-09-26
Genre: Medical
ISBN: 084935224X

This reference collects the latest studies on the development, diagnosis, and treatment of childhood asthma and offers current perspectives on new technologies that will shape the management of pediatric asthma in the forthcoming decade-illustrating how advances in pulmonary function measurement, inflammatory markers, imaging, and pharmacogenetics