Downstream Processing In Biotechnology Recovery And Purification Of Bioproducts And Recovery Of Bioproducts
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Downstream Processing in Biotechnology
Author | : Venko N. Beschkov |
Publisher | : Walter de Gruyter GmbH & Co KG |
Total Pages | : 211 |
Release | : 2021-06-21 |
Genre | : Science |
ISBN | : 3110574004 |
The current book gives an excellent insight into downstream processing technology and explains how to establish a successful strategy for an efficient recovery, isolation and purification of biosynthetic products. In addition to the overview of purification steps and unit operations, the authors provide practical information on capital and operating costs related to downstream processing.
Downstream Processing and Bioseparation
Author | : Jean-François Hamel |
Publisher | : Washington, D.C. : American Chemical Society |
Total Pages | : 328 |
Release | : 1990 |
Genre | : Science |
ISBN | : |
This new volume examines the state of the art of several important separation processes as they relate to biotechnology. Focusing on isolation and purification of downstream processing, it presents recent research results of several promising techniques. Its 15 chapters cover extraction and membrane processing, processes using biospecific interaction with proteins, and novel isolation and purification processes. Many of the chapters contain data that have not been published before. This volume presents the spectrum of current thinking and activities on bioseparation, specifically of large molecules such as proteins and polysaccharides.
Bioprocess Engineering, Downstream Processing and Recovery of Bioproducts, Safety in Biotechnology, Regulations in Biotechnology: Bioprocess engineering; Downstream processing and recovery of bioproducts; Safety in biotechnology; Regulations in biotechnology
Author | : Dieter Behrens |
Publisher | : |
Total Pages | : 548 |
Release | : 1990 |
Genre | : Biotechnology |
ISBN | : 9780895739247 |
Aqueous Two-Phase Systems for Bioprocess Development for the Recovery of Biological Products
Author | : Marco Rito-Palomares |
Publisher | : Springer |
Total Pages | : 196 |
Release | : 2017-07-18 |
Genre | : Technology & Engineering |
ISBN | : 3319593099 |
This comprehensive and unique text presents a full overview of downstream processing useful for those new to the concept as well as professionals with experience in the area. The history and theoretical principles of Aqueous Two-Phase Systems (ATPS) are covered in depth. Information on ATPS characterization and application is included, and ATPS equilibria and system parameters that have significant effect on partition behavior are studied. Aqueous Two-Phase Systems for Bioprocess Development for the Recovery of Biological Products addresses specific applications of ATPS for the recovery and partial purification of high molecular weight compounds such as proteins, nucleic acids and polysaccharides, particulate bioproducts such as cells and organelles and low molecular weight compounds. Non-conventional strategies involving ATPS such as affinity systems, continuous liquid-liquid fractionation stages and the recovery from plant extracts are presented. Economic analysis of the application of ATPS in comparison to other fractionation techniques, particularly liquid chromatography, is considered, as are opportunity and current trends in the ATPS research area. Each chapter utilizes the contributors' experimental expertise in traditional and non-conventional ATPS strategies, as well as analysis of areas of opportunity and perspectives on the development and future applications of ATPS in both the lab and larger scale operations. The result is a thorough and singular overview of ATPS which has not been matched by any other text on the market.
Recovery of Bioproducts
Author | : G. Schmidt-Kastner |
Publisher | : |
Total Pages | : 130 |
Release | : 1993-01-01 |
Genre | : Biological products |
ISBN | : 9780901001795 |
UPSTREAM AND DOWNSTREAM PROCESSING OF BIOPRODUCTS
Author | : R. Puvanakrishnan |
Publisher | : MJP Publisher |
Total Pages | : 241 |
Release | : 2019-06-20 |
Genre | : Technology & Engineering |
ISBN | : |
Microorganisms have been exploited for many centuries for the production of fermented foods and beverages and for bread-making. The production of alcoholic beverages using microbes was the first major industrialized process. The technology developed for large-scale brewing was adapted for other anaerobic processes such as acetone and butanol in the early 1900s. With the discovery of penicillins, rapid developments were made in the technology of submerged culture fermentation of aerobic microorganisms under controlled conditions. The advancements in microbiology and process biochemistry improved our ability to harness the potential of microorganisms through improved bioprocessing methods to manufacture new products with economic viability. Microbial derived bioproducts have been gaining importance in the food, pharmaceutical, textile, leather, cosmetic and chemical industries, and most important among them are therapeutic proteins and peptides, enzymes, antigens, vaccines, antibiotics, drugs, etc.Not all microbial production processes involve culture of the organism in liquid medium. Instead, the organism can be grown on the surface of a solid substrate. Solid substrate (or solid state) fermentation (SSF) is an established traditional technology in many countries, producing edible mushrooms, fungal- fermented foods and soy sauce. Before the development of processes in liquid culture, citric acid and some microbial enzymes were produced by SSF. Carbon composting is also a form of SSF.
Engineering Principles in Biotechnology
Author | : Wei-Shou Hu |
Publisher | : John Wiley & Sons |
Total Pages | : 502 |
Release | : 2017-11-13 |
Genre | : Science |
ISBN | : 1119159024 |
This book is a short introduction to the engineering principles of harnessing the vast potential of microorganisms, and animal and plant cells in making biochemical products. It was written for scientists who have no background in engineering, and for engineers with minimal background in biology. The overall subject dealt with is process. But the coverage goes beyond the process of biomanufacturing in the bioreactor, and extends to the factory of cell’s biosynthetic machinery. Starting with an overview of biotechnology and organism, engineers are eased into biochemical reactions and life scientists are exposed to the technology of production using cells. Subsequent chapters allow engineers to be acquainted with biochemical pathways, while life scientist learn about stoichiometric and kinetic principles of reactions and cell growth. This leads to the coverage of reactors, oxygen transfer and scale up. Following three chapters on biomanufacturing of current and future importance, i.e. cell culture, stem cells and synthetic biology, the topic switches to product purification, first with a conceptual coverage of operations used in bioseparation, and then a more detailed analysis to provide a conceptual understanding of chromatography, the modern workhorse of bioseparation. Drawing on principles from engineering and life sciences, this book is for practitioners in biotechnology and bioengineering. The author has used the book for a course for advanced students in both engineering and life sciences. To this end, problems are provided at the end of each chapter.