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| Author | : Nadrian C. Seeman |
| Publisher | : Cambridge University Press |
| Total Pages | : 269 |
| Release | : 2015 |
| Genre | : Computers |
| ISBN | : 0521764483 |
Written by the founder of the field, this is a comprehensive and accessible introduction to structural DNA nanotechnology.
| Author | : Chunhai Fan |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 361 |
| Release | : 2013-03-12 |
| Genre | : Technology & Engineering |
| ISBN | : 3642360777 |
DNA nanotechnology: From structure to function presents an overview of various facets of DNA nanotechnology, with a particular focus on their promising applications. This book is composed of three parts. Part I, Elements of DNA Nanotechnology, provides extensive basic information on DNA nanotechnology. Part II, Static and Dynamic DNA Nanotechnology, describes the design and fabrication of static and dynamic DNA nanostructures. Recent advances in DNA origami, DNA walkers and DNA nanodevices are all covered in this part. Part III, Applications of DNA Nanotechnology, introduces a variety of applications of DNA nanotechnology, including biosensing, computation, drug delivery, etc. Together these provide a comprehensive overview of this emerging area and its broad impact on biological and medical sciences. This book is intended for post-graduates, post-doctoral researchers and research scientists who are interested in expanding their knowledge of DNA nanotechnology. It provides readers an impression of the latest developments in this exciting filed.
| Author | : Giampaolo Zuccheri |
| Publisher | : Humana Press |
| Total Pages | : 334 |
| Release | : 2018-06-21 |
| Genre | : Science |
| ISBN | : 9781493985814 |
This second edition provides new and updated methods that detail new DNA nanotechnology techniques. Chapters focus on DNA origami nanostructures for arranging matter in the nanoscale or on their manipulation with the aid of other technologies, on procedures for making nucleic acids nanostructures of different kinds, and methods to simulate complex nanostructures or to use them in biosensing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, DNA Nanotechnology: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.
| Author | : Guozhong Cao |
| Publisher | : World Scientific |
| Total Pages | : 650 |
| Release | : 2006 |
| Genre | : Science |
| ISBN | : 9812705643 |
The first volume in an exciting new series, Annual Review of Nano Research, this formidable collection of review articles sees renowned contributors from eight different countries tackle the most recent advances in nanofabrication, nanomaterials and nanostructures.The broad coverage of topics in nanotechnology and nanoscience also includes a special focus on the hot topic of biomedical applications of nanomaterials. The important names contributing to the volume include: M R Bockstaller (USA), L Duclaux (France), S Forster (Germany), W Fritzsche (Germany), L Jiang (China), C Lopez (Spain), W J Parak (Germany), B Samori (Italy), U S Schubert (The Netherlands), S Shinkai (Japan), A Stein (USA), S M Hou (China), and Y N Xia (USA).The volume serves both as a handy reference for experts active in the field and as an excellent introduction to scientists whose expertise lies elsewhere but who are interested in learning about this cutting-edge research area.
| Author | : Giuseppe Domenico Arrabito |
| Publisher | : World Scientific |
| Total Pages | : 216 |
| Release | : 2017-09-25 |
| Genre | : Science |
| ISBN | : 1786343819 |
This book is intended for non-specialists and students, presenting a unique introduction to the field of DNA nanotechnology. The primary focus is on the extraordinary advantages of specificity and sensitivity obtained by integrating DNA nanostructures in bioanalytical devices.DNA Nanotechnology for Bioanalysis provides a concise and rigorous description for the fabrication of various types of functional nanostructures by optimized software-aided high-yield synthesis. Following this is the explanation of methods to decorate these nanostructures with molecules such as proteins, metal nanoparticles or bioorganic moieties covalently bonded onto DNA via self-assemblage processes. Also provided is a concise review on non-canonical DNA structures (such as G-quadruplexes) and their targeting by small molecules for applications in pharmacology. Finally, it describes the exciting applications of DNA nanostructures in life sciences and nanomedicine, including ultraspecific molecular delivery, control of cell behavior, analysis of cell lysate and DNA-based nano-tools for super-resolution sub-cellular imaging.
| Author | : Ravin Narain |
| Publisher | : Woodhead Publishing |
| Total Pages | : 303 |
| Release | : 2016-01-09 |
| Genre | : Science |
| ISBN | : 0081005210 |
Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy. - Explores current challenges in the research of genetic diseases - Discusses polymers for gene therapy and their function in designing advanced materials - Provides examples of organic and inorganic nanomaterials for gene therapy - Includes labeling, targeting, and assays - Looks at characterization, physico-(bio)chemical properties, and applications
| Author | : Oleg Gang |
| Publisher | : |
| Total Pages | : |
| Release | : 2020 |
| Genre | : Nanostructured materials |
| ISBN | : 9789811217975 |
| Author | : Yunfeng Lin |
| Publisher | : John Wiley & Sons |
| Total Pages | : 229 |
| Release | : 2024-07-15 |
| Genre | : Science |
| ISBN | : 3527352058 |
Learn about the cutting-edge nanotechnologies which play an important role in clinical and medical therapies Nucleic acids, the biomolecules which carry most of nature's critical genetic information, are an omnipresent component of life on earth. Nanomaterials incorporating or otherwise built around nucleic acids and their key properties have a number of clinical and medical applications, including drug delivery and more. Biomaterials scientists and other professionals in these fields can benefit enormously from increased knowledge of these invaluable materials. Nucleic Acid-Based Nanomaterials supplies a thorough, rigorous overview of these materials and their possible applications. Beginning with an introduction to the history of nanomaterials and their nucleic-acid-based subcategories, the book offers a detailed and state-of-the-art survey of the current research into these molecules, efforts to increase their biostability, and their incorporation into a range of industries. The result is an essential contribution to materials science in a variety of life-saving contexts. Nucleic Acid-Based Nanomaterials readers will also find: Application-oriented structure which grounds general concepts in their specific instantiations Detailed discussion of applications including drug delivery, tissue engineering, antimicrobial therapy, and more A rigorous yet accessible approach suitable for both academia and industry Nucleic Acid-Based Nanomaterials is ideal for chemists of all types, particularly biochemists and medical chemists, and those in industry.
| Author | : Tao Song |
| Publisher | : World Scientific |
| Total Pages | : 299 |
| Release | : 2019-04-05 |
| Genre | : Computers |
| ISBN | : 9813143193 |
Bio-inspired computing (BIC) focuses on the designs and developments of computer algorithms and models based on biological mechanisms and living phenomena. It is now a major subfield of natural computation that leverages on the recent advances in computer science, biology and mathematics.The ideas provide abundant inspiration to construct high-performance computing models and intelligent algorithms, thus enabling powerful tools to solve real-life problems.Written by world-renowned researchers, this compendium covers the most influential topics on BIC, where the newly-obtained algorithms, developments and results are introduced and elaborated. The potential and valuable directions for further research are addressed as well.
| Author | : Surendra Nimesh |
| Publisher | : Woodhead Publishing |
| Total Pages | : 258 |
| Release | : 2017-04-04 |
| Genre | : Medical |
| ISBN | : 0081005636 |
Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. - Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies - Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. - Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field
