Diagnostic Microbiology of the Immunocompromised Host

Diagnostic Microbiology of the Immunocompromised Host
Author: Randall T. Hayden
Publisher: John Wiley & Sons
Total Pages: 816
Release: 2020-07-16
Genre: Medical
ISBN: 1555819044

Strategies for providing optimal care to this high-risk patient group The immunocompromised patient population is increasing throughout the world. Major advances in transplantation techniques have expanded access to lifesaving therapies and improved outcomes in these high-risk populations. An understanding of the biology of these infections, host conditions, and the limitations of technologies used to detect and quantify such pathogens is critical to optimal care. This new edition of Diagnostic Microbiology of the Immunocompromised Host covers all aspects of state-of-the-art diagnostics for infectious complications in the immunocompromised patient. Editors Randall Hayden, Karen Carroll, Yi-Wei Tang and Donna Wolk, assembled the contributions of a team of preeminent authors to discuss a broad range of topics, including relevant aspects of host biology, antineoplastic, and transplantation techniques and the basis of immunosuppressive conditions ranging from diabetes to age-related immunosuppression approaches, interpretations, and limitations of laboratory diagnosis of infections by a wide range of specific etiologic agents laboratory diagnosis of infections of specific organ systems, such as respiratory tract infections, gastrointestinal tract infections, and central nervous system infections special topics such as prosthetic devices and catheters, healthcare acquired infections, and morphologic considerations (anatomic pathology) future diagnostic technologies and their potential impact on the field Diagnostic Microbiology of the Immunocompromised Host is a resource for laboratory medicine specialists, pathologists, technologists, students, and clinical care professionals who are involved or interested in the care of the immunocompromised host. If you are looking for online access to the latest clinical microbiology content, please visit www.wiley.com/learn/clinmicronow.

Management of Infections in the Immunocompromised Host

Management of Infections in the Immunocompromised Host
Author: Brahm H. Segal
Publisher: Springer
Total Pages: 0
Release: 2018-07-03
Genre: Medical
ISBN: 9783319776729

This book provides a comprehensive, state-of-the-art review of the concepts vital to a modern treatment of common and opportunistic infections in the immunocompromised host. Chapters are written by experts in the field, and include their views on gaps in the field and future directions of research. This book begins with an overview of the normally functioning immune system followed by a detailed discussion of the major primary immunodeficiencies. Specific chapters are dedicated to providing practical knowledge in the prevention and treatment of infections in specific immunocompromised patients, including those with cancer, transplant recipients, HIV infection, and autoimmune disorders. Emphasis is placed on diagnostic evaluation, antimicrobial selection that includes consideration of the threat of antimicrobial-resistant pathogens, and immunotherapy tailored to specific patients. Finally, dedicated chapters on stem cell transplantation for patients with primary immunodeficiencies, adoptive cellular immunotherapy, and gene therapy will provide readers with insight into these rapidly evolving and cutting edge therapies.Management of Infections in the Immunocompromised Host is a valuable resource for infectious diseases specialists, immunologists, oncologists, hematologists, general physicians, students, researchers, and all other working with immunocompromised patients.

Antimicrobial Chemotherapy

Antimicrobial Chemotherapy
Author: Roger Finch
Publisher: OUP Oxford
Total Pages: 409
Release: 2012-01-05
Genre: Medical
ISBN: 0191628654

Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the need for a thorough understanding of the advantages and risks associated with specific antibiotic choices. This sixth edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs. This new edition is updated to include the most recently licensed agents, notably in the treatment of viral infections including HIV/AIDS, and contains new guidance on prescribing practice and infection control practices that limit the development and spread of resistant organisms.

Diagnostic Pathology of Infectious Disease E-Book

Diagnostic Pathology of Infectious Disease E-Book
Author: Richard L. Kradin
Publisher: Elsevier Health Sciences
Total Pages: 715
Release: 2017-04-26
Genre: Medical
ISBN: 0323508677

Comprehensive and up to date, the Second Edition of Diagnostic Pathology: Infectious Disease, by Dr. Richard Kradin, is an invaluable tool for the accurate diagnosis of any infectious disease―from the common to the most challenging. The organ-based format makes it an especially useful tool for surgical pathologists' daily diagnostic and management issues. High-quality, full-color illustrations and differential diagnosis tables accompany each lesion, clearly depicting how to recognize the morphology of organisms and the spectrum of histological responses that they may cause. - Addresses the most difficult diagnostic issues that practicing or trainee surgical pathologists face when handling infectious disease tissue specimens. - Highlights morphological characteristics and landmarks of tissue samples for easy access to information necessary for signing out a specimen. - Emphasizes the host responses critical in differential diagnosis to serve as a second opinion when non-infectious diagnoses mimic and confound the diagnosis of infection. - Completely revised with the latest diagnostic support and hot topics in the field: - A new chapter on novel techniques in microbiology - A new chapter on eye infections - New coverage of immunohistochemical staining and other molecular diagnostic techniques - New discussions of human papillomavirus, a critical tool in predictive cancer screening - New information on infections in the immunocompromised host and related special considerations - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos (including video updates), glossary, and references from the book on a variety of devices.

Treating Infectious Diseases in a Microbial World

Treating Infectious Diseases in a Microbial World
Author: National Research Council
Publisher: National Academies Press
Total Pages: 102
Release: 2006-01-03
Genre: Medical
ISBN: 0309180686

Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.

Infectious Diseases A Clinical Short Course 3/E

Infectious Diseases A Clinical Short Course 3/E
Author: Frederick S. Southwick
Publisher: McGraw Hill Professional
Total Pages: 480
Release: 2013-10-22
Genre: Medical
ISBN: 007178926X

LEARN THE PRINCIPLES OF CLINICAL INFECTIOUS DISEASES IN JUST THIRTY DAYS Infectious Diseases: A Clinical Short COURSE is a concise overview of this important field designed to help the busy physician, medical student, nurse practitioner, and physician assistant to understand, diagnose, and treat common infectious diseases. This unique self-instruction book is organized by system/region as opposed to pathogens—simulating how common pathogens and disorders would be encountered in rounds or in practice. By indicating the number of days that should be allotted to the study of each chapter, the author has created a schedule for completion of each lesson. A wide array of tables that summarize the methods of clinical assessment, anti-infective agent doses, and drug toxicities--facts that do not require memorization, but do need to be referred to when caring for patients--facilitate this condensed learning schedule. There is no better resource for learning to associate pathogens with the corresponding impact on patients than Infectious Diseases. FEATURES Key Points summarize the most important facts when managing each infection and facilitate board review Guiding Questions begin each chapter An estimate of the potential severity of each disease gives you a sense of how quickly you should initiate treatment Numerous case examples highlight real-world clinical application of the content Dozens of color plates depict major pathogens All chapters have been updated to reflect the most current treatment and diagnostic guidelines from the Infectious Diseases Society of America NEW! Antibiograms for each major antibiotic class provide a visual depiction of the spectrum of each individual antibiotic; a table listing the most commonly used outpatient antibiotics and their dosing; and much more

Textbook of Diagnostic Microbiology - E-Book

Textbook of Diagnostic Microbiology - E-Book
Author: Connie R. Mahon
Publisher: Elsevier Health Sciences
Total Pages: 1090
Release: 2018-01-18
Genre: Medical
ISBN: 0323482120

Learn to develop the problem-solving skills necessary for success in the clinical setting! The Textbook of Diagnostic Microbiology, 6th Edition uses a reader-friendly "building-block" approach to the essentials of diagnostic microbiology. This updated edition has new content on viruses like Zika, an expanded molecular chapter, and the latest information on prevention, treatment modalities, and CDC guidelines. Updated photos offer clear examples of automated lab instruments, while case studies, review questions, and learning objectives present information in an easy-to-understand, accessible manner for students at every level. - A building-block approach encourages you to use previously learned information to sharpen critical-thinking and problem-solving skills. - Full-color design, with many full-color photomicrographs, prepares you for the reality of diagnostic microbiology. - A case study at the beginning of each chapter provides you with the opportunity to form your own questions and answers through discussion points. - Hands-on procedures describe exactly what takes place in the micro lab, making content more practical and relevant. - Agents of bioterrorism chapter furnishes you with the most current information about this hot topic. - Issues to Consider boxes encourages you to analyze important points. - Case Checks throughout each chapter tie content to case studies for improved understanding. - Bolded key terms at the beginning of each chapter equip you with a list of the most important and relevant terms in each chapter. - Learning objectives at the beginning of each chapter supply you with a measurable outcome to achieve by completing the material. - Review questions for each learning objective help you think critically about the information in each chapter, enhancing your comprehension and retention of material. - Learning assessment questions at the conclusion of each chapter allow you to evaluate how well you have mastered the material. - Points to Remember sections at the end of each chapter identify key concepts in a quick-reference, bulleted format. - An editable and printable lab manual provides you with additional opportunities to learn course content using real-life scenarios with questions to reinforce concepts. - Glossary of key terms at the end of the book supplies you with a quick reference for looking up definitions. - NEW! Content about Zika and other viruses supplies students with the latest information on prevention, treatment modalities, and CDC guidelines. - NEW! Expanded Molecular Diagnostics chapter analyzes and explains new and evolving techniques. - NEW! Updated photos helps familiarize you with the equipment you'll use in the lab. - NEW! Reorganized and refocused Mycology chapter helps you better understand the toxicity of fungi. - NEW! Updated content throughout addresses the latest information in diagnostic microbiology.

SARS, MERS and other Viral Lung Infections

SARS, MERS and other Viral Lung Infections
Author: David S. Hui
Publisher: European Respiratory Society
Total Pages: 148
Release: 2016-06-01
Genre: Medical
ISBN: 1849840709

Viral respiratory tract infections are important and common causes of morbidity and mortality worldwide. In the past two decades, several novel viral respiratory infections have emerged with epidemic potential that threaten global health security. This Monograph aims to provide an up-to-date and comprehensive overview of severe acute respiratory syndrome, Middle East respiratory syndrome and other viral respiratory infections, including seasonal influenza, avian influenza, respiratory syncytial virus and human rhinovirus, through six chapters written by authoritative experts from around the globe.

Cytopathology of Infectious Diseases

Cytopathology of Infectious Diseases
Author: PANTANOWITZ LIRON
Publisher: Springer Science & Business Media
Total Pages: 406
Release: 2011-12-02
Genre: Medical
ISBN: 1461402425

Cytopathology of Infectious Diseases is the first book of its kind to focus entirely on the cytopathology of infectious diseases. It contains all of the pertinent information about the cytology of infectious diseases and microorganisms and will serve as an ideal handy reference. This unique volume covers the cytomorphology of various microorganisms and the host reactions they elicit, and also incorporates an update on advances in the field. Newly recognized infections such as the recent discovery of the Merkel Cell Polyomavirus (MCV) are included, as well as the utility of new immunostains (e.g. CM2B4 for MCV) and the role of molecular techniques that assist in the identification, classification and even quantification of microorganisms. Each chapter is succinctly written and concisely referenced with key published articles and resources. The volume includes practical pointers, useful diagnostic criteria, differential diagnoses and potential pitfalls. Many color images of high resolution that illustrate microorganisms (e.g. branching hyphae) and host reactions (e.g. viral cytopathic effect) are included throughout. Relevant tables with diagrams that provide quick reference guides are incorporated. Cytopathology of Infectious Diseases will serve as a valuable reference tool for cytopathologists, anatomical/clinical pathologists, cytotechnologists, pathology residents and cytopathology fellows.

Medical Microbiology Illustrated

Medical Microbiology Illustrated
Author: S. H. Gillespie
Publisher: Butterworth-Heinemann
Total Pages: 297
Release: 2014-06-28
Genre: Science
ISBN: 1483193632

Medical Microbiology Illustrated presents a detailed description of epidemiology, and the biology of micro-organisms. It discusses the pathogenicity and virulence of microbial agents. It addresses the intrinsic susceptibility or immunity to antimicrobial agents. Some of the topics covered in the book are the types of gram-positive cocci; diverse group of aerobic gram-positive bacilli; classification and clinical importance of erysipelothrix rhusiopathiae; pathogenesis of mycobacterial infection; classification of parasitic infections which manifest with fever; collection of blood for culture and control of substances hazardous to health. The classification and clinical importance of neisseriaceae is fully covered. The definition and pathogenicity of haemophilus are discussed in detail. The text describes in depth the classification and clinical importance of spiral bacteria. The isolation and identification of fungi are completely presented. A chapter is devoted to the laboratory and serological diagnosis of systemic fungal infections. The book can provide useful information to microbiologists, physicians, laboratory scientists, students, and researchers.