Development Of Alkali Metal In Silica Gel M Sg As A Reagent In Organic Reactions
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Green Techniques for Organic Synthesis and Medicinal Chemistry
Author | : Wei Zhang |
Publisher | : John Wiley & Sons |
Total Pages | : 1127 |
Release | : 2018-01-18 |
Genre | : Science |
ISBN | : 1119288584 |
An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.
Modeling Marvels
Author | : Errol G. Lewars |
Publisher | : Springer Science & Business Media |
Total Pages | : 287 |
Release | : 2008-12-05 |
Genre | : Science |
ISBN | : 1402069731 |
The aim of this highly original book is to survey a number of chemical compounds that some chemists, theoretical and experimental, find fascinating. This is the first book to feature compounds/classes of compounds of theoretical interest that have been studied theoretically but have defied synthesis. It is hoped that this collection of idiosyncratic molecules will appeal to chemists who find the study of chemical oddities interesting and, on occasion, even rewarding.
Side Reactions in Organic Synthesis
Author | : Florencio Zaragoza Dörwald |
Publisher | : John Wiley & Sons |
Total Pages | : 389 |
Release | : 2006-03-06 |
Genre | : Science |
ISBN | : 3527604987 |
Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating, but also cost a lot of time and money. Many failures may, however, be avoided by understanding the structure-reactivity relationship of organic compounds. This textbook highlights the competing processes and limitations of the most important reactions used in organic synthesis. By allowing chemists to quickly recognize potential problems this book will help to improve their efficiency and success-rate. A must for every graduate student but also for every chemist in industry and academia. Contents: 1 Organic Synthesis: General Remarks 2 Stereoelectronic Effects and Reactivity 3 The Stability of Organic Compounds 4 Aliphatic Nucleophilic Substitutions: Problematic Electrophiles 5 The Alkylation of Carbanions 6 The Alkylation of Heteroatoms 7 The Acylation of Heteroatoms 8 Palladium-Catalyzed C-C Bond Formation 9 Cyclizations 10 Monofunctionalization of Symmetric Difunctional Substrates
Applications of Transition Metal Catalysis in Drug Discovery and Development
Author | : Matthew L. Crawley |
Publisher | : John Wiley & Sons |
Total Pages | : 386 |
Release | : 2012-05-14 |
Genre | : Science |
ISBN | : 1118309839 |
This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development – it is a guide, a historical prospective, a practical compendium, and a source of future direction for the field.
Supported Catalysts and Their Applications
Author | : David C Sherrington |
Publisher | : Royal Society of Chemistry |
Total Pages | : 282 |
Release | : 2007-10-31 |
Genre | : Science |
ISBN | : 1847551963 |
The need to improve both the efficiency and environmental acceptability of industrial processes is driving the development of heterogeneous catalysts across the chemical industry, including commodity, specialty and fine chemicals and in pharmaceuticals and agrochemicals. Drawing on international research, Supported Catalysts and their Applications discusses aspects of the design, synthesis and application of solid supported reagents and catalysts, including supported reagents for multi-step organic synthesis; selectivity in oxidation catalysis; mesoporous molecular sieve catalysts; and the use of Zeolite Beta in organic reactions. In addition, the two discrete areas of heterogeneous catalysis (inorganic oxide materials and polymer-based catalysts) that were developing in parallel are now shown to be converging, which will be of great benefit to the whole field. Providing a snapshot of the state-of-the-art in this fast-moving field, this book will be welcomed by industrialists and researchers, particularly in the agrochemicals and pharmaceuticals industries.
Carbanions, Living Polymers and Electron Transfer Processes
Author | : Michael Szwarc |
Publisher | : John Wiley & Sons |
Total Pages | : 720 |
Release | : 1968-01-15 |
Genre | : Science |
ISBN | : |
Chemistry of Zeolites and Related Porous Materials
Author | : Ruren Xu |
Publisher | : John Wiley & Sons |
Total Pages | : 616 |
Release | : 2009-05-29 |
Genre | : Science |
ISBN | : 0470822368 |
Widely used in adsorption, catalysis and ion exchange, the family of molecular sieves such as zeolites has been greatly extended and many advances have recently been achieved in the field of molecular sieves synthesis and related porous materials. Chemistry of Zeolites and Related Porous Materials focuses on the synthetic and structural chemistry of the major types of molecular sieves. It offers a systematic introduction to and an in-depth discussion of microporous, mesoporous, and macroporous materials and also includes metal-organic frameworks. Provides focused coverage of the key aspects of molecular sieves Features two frontier subjects: molecular engineering and host-guest advanced materials Comprehensively covers both theory and application with particular emphasis on industrial uses This book is essential reading for researches in the chemical and materials industries and research institutions. The book is also indispensable for researches and engineers in R&D (for catalysis) divisions of companies in petroleum refining and the petrochemical and fine chemical industries.
Zeolite Synthesis
Author | : Mario L. Occelli |
Publisher | : |
Total Pages | : 672 |
Release | : 1989 |
Genre | : Language Arts & Disciplines |
ISBN | : |
This volume is a complete progress report on the various aspects of zeolite synthesis on a molecular level. It provides many examples that illustrate how zeolites can be crystallized and what the important parameters are that control crystallization. Forty-two chapters cover such topics as: crystallization techniques; gel chemistry; crystal size and morphology; the role of organic compounds; and novel synthesis procedures. It offers a complete review of zeolite synthesis as well as the latest finding in this important field. Contains benchmark contributions from many notable pioneers in the field, including R.M. Barrer, H. Robson, and Robert Milton.
Crystal Growth in Gels
Author | : Heinz K. Henisch |
Publisher | : Courier Corporation |
Total Pages | : 132 |
Release | : 1996-01-01 |
Genre | : Science |
ISBN | : 9780486689159 |
First book ever printed on growing crystals in a gel medium provides thorough descriptions of the procedure, its history and future potential. "Concise and readable."—Science. 42 illus. 1970 edition.