Next-Generation Antimicrobial Nanocoatings for Medical Devices and Implants

Next-Generation Antimicrobial Nanocoatings for Medical Devices and Implants
Author: Pratima R. Solanki
Publisher: Elsevier
Total Pages: 317
Release: 2024-01-12
Genre: Technology & Engineering
ISBN: 0323957579

Next-Generation Antimicrobial Nanocoatings for Medical Devices and Implants provides a detailed, up-to-date overview of nano-based antimicrobial coatings used to combat medical device-related biofilms. An introduction to biofilms and how they infect medical devices is included, as well as strategies/modification techniques used to target these biofilms. This book evaluates the various antimicrobial coatings formed using nanomaterials such as silver, inorganic materials, organic materials, carbon dots, surfactants, and electrospun fibers, specifically for us on medical devices and implants. Numerous coating methods are discussed along with the biological characterizations of these coating materials, and their toxicological and environmental impact.Next-generation Antimicrobial Nanocoatings for Medical Devices and Implants is a useful reference for materials scientists, biomedical engineers, and those working on the development of novel biomaterials for use in medical devices and implants. Provides a range of nanomaterials for use in antimicrobial coatings, including electrospun fibers, surfactants, carbon quantum dots, and more Details various modification approaches for targeting biofilms, as well as nanocoating characterization and methods for use on medical devices and implants Assesses the environmental and toxicological impact of antimicrobial nanocoatings

Silver Nanoparticles for Antibacterial Devices

Silver Nanoparticles for Antibacterial Devices
Author: Huiliang Cao
Publisher: CRC Press
Total Pages: 634
Release: 2017-05-18
Genre: Medical
ISBN: 1315353474

Since the potential toxicity of silver nanoparticles (Ag NPs) has raised serious concerns in the biomaterials and biomedical engineering community, Silver Nanoparticles for Antibacterial Devices: Biocompatibility and Toxicity brings together the synthesis, the physicochemical properties and the biological actions of Ag NPs, as well as the clinical demands for fabricating antibacterial medical devices, discussing how to suppress the side effects of nanomaterials and how to impart to them the selective toxicity. This book presents the two primary paradigms that have emerged in probing the antibacterial applications of Ag NPs, i.e. the active attacking releasing way and the conservative defending approach by taking advantage of various short-range actions; it shows readers how the ways in which Ag NPs have behaved can be engineered purposively. With contributions from leading international experts and extensive references listed in each chapter, this volume provides the general principles on controlling the physicochemical behaviors of nanomaterials and managing their toxicity risks.

Biofilms and Implantable Medical Devices

Biofilms and Implantable Medical Devices
Author: Ying Deng
Publisher: Woodhead Publishing
Total Pages: 240
Release: 2016-10-24
Genre: Technology & Engineering
ISBN: 0081003986

Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention. Provides useful information on the fundamentals of biofilm problems in medical devices Discusses biofilm problems in a range of medical devices Focuses on strategies for prevention of biofilm formation

Nanobiomaterials Science, Development and Evaluation

Nanobiomaterials Science, Development and Evaluation
Author: Mehdi Razavi
Publisher: Woodhead Publishing
Total Pages: 341
Release: 2017-05-22
Genre: Technology & Engineering
ISBN: 0081009682

Nanobiomaterials Science, Development and Evaluation examines the practical aspects of producing nanostructured biomaterials for a range of applications. With a strong focus on materials, such as metals, ceramics, polymers, and composites, the book also examines nanostructured coatings and toxicology aspects. Chapters in Part One look at materials classes and their synthesis with information on all major material groups. Part Two focuses on nanostructured coatings and practical aspects associated with the use of nanobiomaterials in vivo. This book brings together the work of international contributors who are actively engaged on the forefront of research in their respective disciplines, and is a valuable resource for materials scientists in academia, industry, and all those who wish to broaden their knowledge in the allied field. Focuses on the synthesis and evaluation techniques for a range of nanobiomaterials Examines nanostructured inorganic coatings for biomaterials Discusses issues related to the toxicology of nanobiomaterials Presents the practical aspects of nanobiomaterials

Biomaterial-Related Infections

Biomaterial-Related Infections
Author: Natália Martins
Publisher: MDPI
Total Pages: 204
Release: 2020-12-23
Genre: Medical
ISBN: 3039434381

The use of medical devices (e.g., catheters, implants, and probes) is a common and essential part of medical care for both diagnostic and therapeutic purposes. However, these devices quite frequently lead to the incidence of infections due to the colonization of their abiotic surfaces by biofilm-growing microorganisms, which are progressively resistant to antimicrobial therapies. Several methods based on anti-infective biomaterials that repel microbes have been developed to combat device-related infections. Among these strategies, surface coating with antibiotics (e.g., beta-lactams), natural compounds (e.g., polyphenols), or inorganic elements (e.g., silver and copper nanoparticles) has been widely recognized as exhibiting broad-spectrum bactericidal or bacteriostatic activity. So, in order to achieve a better therapeutic response, it is crucial to understand how these infections are different from others. This will allow us to find new biomaterials characterized by antifouling coatings with repellent properties or low adhesion towards microorganisms, or antimicrobial coatings that are capable of killing microbes approaching the surface, improving biomaterial functionalization strategies and supporting tissues’ bio-integration.

Nanotechnology in Medicine and Biology

Nanotechnology in Medicine and Biology
Author: Huinan H. Liu
Publisher: Elsevier
Total Pages: 296
Release: 2021-11-13
Genre: Technology & Engineering
ISBN: 0128226714

Nanotechnology in Medicine and Biology brings together a multidisciplinary team of experts from the fields of materials science, nanotechnology, medicine and biomedical engineering to introduce new nanoscale biomaterials and their applications, diagnosis and treatment of disorders of the human body. The book presents the fundamentals for understanding the design, properties and selection of nanobiomaterials as well as their real-world applications in medicine. Each chapter addresses current regulations, manufacturing processes, and translation issues of nanobiomaterials for key applications. A discussion of current protocols and their benefits and disadvantages is also included. This book provides comprehensive background and knowledge in the field of nanobiomaterials that is suitable for academics, scientists and clinicians. Provides fundamental understanding on the design, properties and selection of biomaterials for applications in medicine and biology Reviews current regulations, protocols, manufacturing processes and translation issues of nanobiomaterials for medical applications Discusses tissue repair, wound healing, regenerative medicine, drug delivery, imaging and medical device applications

Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance

Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance
Author: Muthupandian Saravanan
Publisher: Elsevier
Total Pages: 790
Release: 2022-06-22
Genre: Technology & Engineering
ISBN: 0323998100

Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance focuses on recent and emerging trends surrounding nanomaterials and nano-drug delivery approaches to combat antimicrobial resistance. The relationship between nanomaterials and antimicrobial activity needs to be deeply explored to meet the challenges of combating antimicrobial resistance. The content of this book is divided into three main topic areas, including (i) how to overcome the existing traditional approaches to combat antimicrobial resistance, (ii) applying multiple drug delivery mechanisms to target multi-drug resistant microbes, and (iii) how nanomaterials can be used as drug carriers. This is an important reference source for those looking to understand how nanotechnology plays an important role in combatting disease and infection. As antimicrobial resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses, and fungi, this is a timely resource. Outlines how to overcome existing traditional approaches to combatting antimicrobial resistance Explains how to apply multiple drug delivery mechanisms (MDR) to the target area in order to better combat antimicrobial resistance Shows how nanomaterials are used as drug carriers in this context

Antimicrobial Coatings and Modifications on Medical Devices

Antimicrobial Coatings and Modifications on Medical Devices
Author: Zheng Zhang
Publisher: Springer
Total Pages: 277
Release: 2017-05-24
Genre: Technology & Engineering
ISBN: 3319574949

Based on a fundamental understanding of the interaction between bacteria and materials, this timely volume emphasizes the latest research in the antimicrobial interfacial design and provides an invaluable blueprint for improving antimicrobial performance on devices and products. Antimicrobial Coatings and Modifications targets reduction of microbial accumulation on biomedical and industrial materials through changing interfacial characteristics. Applying a viable antimicrobial coating or modification to resist alarming threats is a highly demanding requirement for many medical and engineering applications. Many contemporary books in the area of antimicrobial solution focus on applying antimicrobial agents or materials that can kill bacteria. The volume pays more attention to eliminating bacterial contamination and biofilm formation through surface characteristics with minimized bacterial resistance and environmental impact.

Nanomedicine

Nanomedicine
Author: Thomas J Webster
Publisher: Woodhead Publishing
Total Pages: 636
Release: 2023-03-14
Genre: Technology & Engineering
ISBN: 0128193018

Nanomedicine: Technologies and Applications, Second Edition provides an important review of this exciting technology and its growing range of applications. In this new edition, all chapters are thoroughly updated and revised, with new content on antibacterial technologies and green nanomedicine. Sections introduce the material, cover their properties, review nanomedicine for therapeutics, imaging and soft tissue engineering, including organ regeneration, skin grafts, nanotubes and self-assembled nanomaterials. Other sections cover bone and cartilage tissue engineering, nanostructured particles for antibacterial purposes, advances in green nanomedicine, and using natural nanomedicine to fight disease. This book is an indispensable guide for all those involved in the research, development and application of this exciting technology, whilst also providing a comprehensive introduction for students and academics interested in this field. Provides an important review of nanomedicine technology and its growing range of applications Discusses key nanomedicine materials and their properties, including nanocrystalline metals, alloys and nanoporous gold and hydroxyapatite coatings Features updated content in all parts, as well as a number of new chapters on antibacterial nanomedicine and green nanomedicine