Design and Synthesis and Testing of Conformationally Constrained Peptidomimetics
Author | : Joanna Duncan |
Publisher | : |
Total Pages | : 544 |
Release | : 2013 |
Genre | : Metathesis (Chemistry) |
ISBN | : |
Download Design And Synthesis And Testing Of Conformationally Constrained Peptidomimetics full books in PDF, epub, and Kindle. Read online free Design And Synthesis And Testing Of Conformationally Constrained Peptidomimetics ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author | : Joanna Duncan |
Publisher | : |
Total Pages | : 544 |
Release | : 2013 |
Genre | : Metathesis (Chemistry) |
ISBN | : |
Author | : Antonio Guarna |
Publisher | : John Wiley & Sons |
Total Pages | : 334 |
Release | : 2014-03-14 |
Genre | : Science |
ISBN | : 1118683145 |
A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or biological activity. It is a very powerful approach for the generation of small-molecule-based drugs as enzyme inhibitors or receptor ligands. Peptidomimetics in Organic and Medicinal Chemistry outlines the concepts and synthetic strategies underlying the building of bioactive compounds of a peptidomimetic nature. Topics covered include the chemistry of unnatural amino acids, peptide- and scaffold-based peptidomimetics, amino acid-side chain isosteres, backbone isosteres, dipeptide isosteres, beta-turn peptidomimetics, proline-mimetics as turn inducers, cyclic scaffolds, amino acid surrogates, and scaffolds for combinatorial chemistry of peptidomimetics. Case studies in the hit-to-lead process, such as the development of integrin ligands and thrombin inhibitors, illustrate the successful application of peptidomimetics in drug discovery.
Author | : Martin Gerald Teresk |
Publisher | : |
Total Pages | : 618 |
Release | : 2008 |
Genre | : Amino acids |
ISBN | : |
Author | : Margaret Claire Evans |
Publisher | : |
Total Pages | : 332 |
Release | : 1999 |
Genre | : Hypothalamic hormones |
ISBN | : |
Author | : Paul W. Baures |
Publisher | : |
Total Pages | : 514 |
Release | : 1995 |
Genre | : Neurophysiology |
ISBN | : |
Author | : William D. Lubell |
Publisher | : Springer |
Total Pages | : 267 |
Release | : 2016-11-25 |
Genre | : Science |
ISBN | : 3319491245 |
The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.