Dendrimers Iii
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Author | : M. Ballauf |
Publisher | : Springer Science & Business Media |
Total Pages | : 206 |
Release | : 2000-11-06 |
Genre | : Medical |
ISBN | : 354067828X |
Dendrimers are a class of highly branched molecules that combine the properties of polymers as well as small discrete molecules. One classified among the exotic molecules of chemistry, dendrimers have attracted considerable attention in recent years, as their unique host/guest properties and their capability of being functionalized in the periphery as well in the core have led to new materials with a great potential for applications. This volume presents the state of art in this blossoming research area, written by pioneers in the fields. Covering the synthetic, supramolecular, stereochemical, host/guest and polymer chemistry of dendritic and hyperbranched molecules, this volume explains both theoretical and practical aspects, including chirality reactivity, mechanism, material properties and biological relevance. It is the most comprehensive and authoritative review of the area available.
Author | : Jean M. J. Fréchet |
Publisher | : John Wiley & Sons |
Total Pages | : 696 |
Release | : 2001 |
Genre | : Science |
ISBN | : |
With contributions from many of the world's leading scientists in the field of dendritic research and development, Dendrimers and Other Dendritic Polymers provides a comprehensive review of this rapidly expanding and exciting new field of polymer science. Of interest to academia and industry alike, this book covers the synthesis, characterization, unique properties, potential for novel applications and technical challenges associated with these polymers. * Detailed coverage of all known subclasses of dendritic polymers, including their properties and synthesis * Insight into the potential commercial applications of dendritic polymers, including drug delivery, cancer therapy, coatings and adhesives * Identification of the key trends and perspectives in dendrimer research * Essential reference for polymer chemists, materials scientists and plastics engineers working in academia and industry alike
Author | : Anil K. Sharma |
Publisher | : CRC Press |
Total Pages | : 406 |
Release | : 2018-07-27 |
Genre | : Medical |
ISBN | : 135136068X |
With chapters from highly skilled, experienced, and renowned scientists and researchers from around the globe, Dendrimers for Drug Delivery provides an abundance of information on dendrimers and their applications in the field of drug delivery. The volume begins with an introduction to dendrimers, summarizing dendrimer applications and the striking features of dendrimers. It goes on to present the details of usual properties, structure, classification, and methods of synthesis, with relevant examples. The toxicity of dendrimers is also discussed. The chapter authors provide an exhaustive amount of information about dendrimers and their biomedical applications, including biocompatibility and toxicity aspects, a very useful feature. This informative volume will be valuable resource that will help readers to create products derived from dendrimers and navigate through the regulatory, manufacturing, and quality control hurdles. It will be an important resource for researchers, scientists, upper-level students, and industry professionals.
Author | : Michael Malkoch |
Publisher | : Royal Society of Chemistry |
Total Pages | : 327 |
Release | : 2020 |
Genre | : Science |
ISBN | : 1788011325 |
An overview of the latest advances in the synthesis, characterization and applications of dendrimers and other complex dendritic architectures.
Author | : Fritz Vögtle |
Publisher | : Springer |
Total Pages | : 317 |
Release | : 2003-07-01 |
Genre | : Science |
ISBN | : 3540465774 |
The second volume on dendrimers is again written by pioneers in the field. Their contributions illuminate the aspects of dendrimers mentioned in the subtitle, and also touch on areas beyond chemistry, namely material sciences as well as biological, medicinal, analytical, and nano aspects.
Author | : Fritz Vögtle |
Publisher | : Springer |
Total Pages | : 248 |
Release | : 2003-09-05 |
Genre | : Science |
ISBN | : 3540697799 |
Dendrimers are a class of highly branched molecules that combine the properties of polymers and small discrete molecules. One classified among the exotic molecules of chemistry, dendrimers have attracted considerable attention in recent years, as their unique host/guest properties and their capability of being functionalized in the periphery as well in the core have led to new materials with a great potential for applications. This volume presents the state of art in this blossoming area, written by pioneers in the fields. Covering the synthetic, supramolecular, stereochemical, host/guest and polymer chemistry of dendritic and hyperbranched molecules, this volume explains both theoretical and practical aspects, including chirality reactivity, mechanism, material properties and biological relevance.
Author | : Neelesh Kumar Mehra |
Publisher | : CRC Press |
Total Pages | : 328 |
Release | : 2021-03-22 |
Genre | : Science |
ISBN | : 1000333035 |
Dendrimers, hyperbranched macromolecules, emerged just few decades ago but show promising potential as drug delivery nanocarriers, theranostic agents and gene vectors; in the pharmaceutical research and innovation area as well as in other healthcare applications. Although tremendous advancements have been made in dendrimer chemistry and their applications since their emergence, the synthesis, development and design of pure and safe dendrimer-based products have been a major challenge in this area. This book, edited by well-known researchers in the area of nanomaterials and drug-based drug delivery applications, exhaustively covers the nanotechnological aspects, concepts, properties, characterisation, application, biofate and regulatory aspects of dendrimers. It includes sixteen vivid chapters by renowned formulators, researchers and academicians from all over the world, highlighting their specialised areas of interest in the fields of chemistry, biology, pharmacy and nanomedicine. Features: • Highlights dendrimers’ advancements in nanomedicine in the development of safe healthcare and biotechnological products • Covers physicochemical aspects, biofate, drug delivery aspects and gene therapy using dendrimers • Covers biomedical application of dendrimers in the field of biological sciences • Gives examples of dendrimer–guest interaction chemistry Dendrimers in Nanomedicine: Concept, Theory and Regulatory Perspectives provides the comprehensive overview of the latest research efforts in designing, optimising, development and scale-up of dendrimer-mediated delivery systems. It analyses the key challenges of synthesis, design, molecular modelling, fundamental concepts, drug delivery aspects, analytical tools and biological fate as well as regulatory consideration to the practical use of dendrimer application. Dr. Neelesh Kumar Mehra Assistant Professor of Pharmaceutics in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He has authored more than sixty peer-reviewed publications in highly reputed international journals, as well as book chapters and contributions on two patents. Dr. Mehra has 11 years of rich research and teaching experience in the formulation and development of complex, innovative biopharmaceutical products including micro- and nanotechnologies for regulated markets. Dr. Keerti Jain Assistant Professor of Pharmaceutics in the Department of Pharmaceutics, NIPER, Raebareli, India. For more than 10 years, she has been actively engaged in formulation and development of nanomedicines. Dr. Jain has supervised masters and doctoral pharmaceutics students in their research works which have been published in high quality, good impact factor journals. She has also authored more than 60 international manuscripts in peer reviewed high impact journals. In 2019, she was awarded the prestigious ICMR-Amir Shakuntala Award.
Author | : Fritz Vögtle |
Publisher | : Springer |
Total Pages | : 254 |
Release | : 2003-07-01 |
Genre | : Science |
ISBN | : 3540450033 |
With contributions by numerous experts.
Author | : Abhay Singh Chauhan |
Publisher | : Elsevier |
Total Pages | : 402 |
Release | : 2019-11-15 |
Genre | : Technology & Engineering |
ISBN | : 0128145285 |
Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. The book discusses the diagnostic applications of dendrimers, including their use as MRI contrast agents and in the imaging of diseased areas. In addition, the anti-inflammatory, antimicrobial and antiviral properties of PPI and PAMAM are also covered, along with a discussion on photosensitizers, such as rose Bengal and protoporphyrin IX that have been delivered using PAMAM and PPI dendrimers for the treatment of cancer. This book is an important research reference for those who want to learn more about the development of dendrimer-based solutions for drug delivery. - Explores the role of dendrimers in the design of dendritic nanoplatforms for targeted drug and gene delivery systems - Discusses the potential of dendrimers in preformulation and formulation development - Addresses both clinical and regulatory challenges in the development of dendrimer-based formulations
Author | : Prashant Kesharwani |
Publisher | : Academic Press |
Total Pages | : 486 |
Release | : 2021-04-14 |
Genre | : Medical |
ISBN | : 0128212519 |
Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related applications. This book covers the history of the area to the most recent research. The starting chapter covers detailed information about basic properties about dendrimers i.e. properties, nomenclature, synthesis methods, types, characterization of dendrimers, safety and toxicity issues of dendrimers. Further chapters discuss the most recent advancements in the field of dendrimer i.e. dendrimer-drug conjugates, PEGylated dendrimer, dendrimer surface engineering, dendrimer hybrids, dendrimers as solubility enhancement, in targeting and delivery of drugs, as photodynamic therapy, in tissue engineering, as imaging contrast agents, as antimicrobial agents, advances in targeted dendrimers for cancer therapy and future considerations of dendrimers. Dendrimer-Based Nanotherapeutics will help the readers to understand the most recent progress in the field of dendrimer-based research, suitable for pharmaceutical scientists, advanced students, and those working in related healthcare fields. - Discusses various routes such as oral, pulmonary, transdermal, delivery and local administration of dendrimer delivery of bioactive - Explores a wide range of applications of dendrimer-based drug delivery using the latest advancements in nanomedicine - Provides the most recent research on dendrimers as well as context and background, providing a useful resource for all levels of researcher