Dendrimer Based Therapeutic Delivery Vehicle For The Treatment Of Ocular Diseases
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| Author | : Prashant Kesharwani |
| Publisher | : Academic Press |
| Total Pages | : 486 |
| Release | : 2021-04-14 |
| Genre | : Medical |
| ISBN | : 0128212519 |
Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related applications. This book covers the history of the area to the most recent research. The starting chapter covers detailed information about basic properties about dendrimers i.e. properties, nomenclature, synthesis methods, types, characterization of dendrimers, safety and toxicity issues of dendrimers. Further chapters discuss the most recent advancements in the field of dendrimer i.e. dendrimer-drug conjugates, PEGylated dendrimer, dendrimer surface engineering, dendrimer hybrids, dendrimers as solubility enhancement, in targeting and delivery of drugs, as photodynamic therapy, in tissue engineering, as imaging contrast agents, as antimicrobial agents, advances in targeted dendrimers for cancer therapy and future considerations of dendrimers. Dendrimer-Based Nanotherapeutics will help the readers to understand the most recent progress in the field of dendrimer-based research, suitable for pharmaceutical scientists, advanced students, and those working in related healthcare fields. - Discusses various routes such as oral, pulmonary, transdermal, delivery and local administration of dendrimer delivery of bioactive - Explores a wide range of applications of dendrimer-based drug delivery using the latest advancements in nanomedicine - Provides the most recent research on dendrimers as well as context and background, providing a useful resource for all levels of researcher
| Author | : Anil K. Sharma |
| Publisher | : CRC Press |
| Total Pages | : 406 |
| Release | : 2018-07-27 |
| Genre | : Medical |
| ISBN | : 135136068X |
With chapters from highly skilled, experienced, and renowned scientists and researchers from around the globe, Dendrimers for Drug Delivery provides an abundance of information on dendrimers and their applications in the field of drug delivery. The volume begins with an introduction to dendrimers, summarizing dendrimer applications and the striking features of dendrimers. It goes on to present the details of usual properties, structure, classification, and methods of synthesis, with relevant examples. The toxicity of dendrimers is also discussed. The chapter authors provide an exhaustive amount of information about dendrimers and their biomedical applications, including biocompatibility and toxicity aspects, a very useful feature. This informative volume will be valuable resource that will help readers to create products derived from dendrimers and navigate through the regulatory, manufacturing, and quality control hurdles. It will be an important resource for researchers, scientists, upper-level students, and industry professionals.
| Author | : Mahendra Rai |
| Publisher | : Springer |
| Total Pages | : 388 |
| Release | : 2017-11-21 |
| Genre | : Medical |
| ISBN | : 3319702998 |
Focusing on the application of nanotechnology in pharmaceutical technology the editors seek to integrate the two in order to obtain innovative products and solutions in pharmacology. Interdisciplinary in content it is of interest to those who are involved in the development of nanoproducts including nanotechnologists, microbiologists, biotechnologists pharmacologists and clinicians. Recent studies are presented that include the biosynthesis of nanoparticles focusing on antimicrobials; nanomaterial-based formulations that treat cancer, infections, skin disorders and wounds;nanomaterials in eye diseases and toxicity and safety issues. It demonstrates the crucial role this plays in tackling multi-drug resistant threats.
| Author | : Ashim K. Mitra |
| Publisher | : CRC Press |
| Total Pages | : 847 |
| Release | : 2019-12-02 |
| Genre | : |
| ISBN | : 9780367446765 |
The second edition of this text assembles significant ophthalmic advances and encompasses breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery.
| Author | : Sougata Jana |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1063 |
| Release | : 2022-04-18 |
| Genre | : Science |
| ISBN | : 3527349049 |
A comprehensive discussion of various types of nanoengineered biomaterials and their applications In Nanoengineering of Biomaterials: Drug Delivery & Biomedical Applications, an expert team of chemists delivers a succinct exploration of the synthesis, characterization, in-vitro and in-vivo drug molecule release, pharmacokinetic activity, pharmacodynamic activity, and the biomedical applications of several types of nanoengineered biomaterials. The editors have also included resources to highlight the most current developments in the field. The book is a collection of valuable and accessible reference sources for researchers in materials chemistry and related disciplines. It uses a functions-directed approach to using organic and inorganic source compounds that translate into biological systems as scaffolds, micelles, dendrimers, and other delivery systems. Nanoengineering of Biomaterials offers readers up-to-date chemistry and material science insights that are readily transferrable to biomedical systems. The book also includes: Thorough introductions to alginate nanoparticle delivery of therapeutics and chitosan-based nanomaterials in biological applications Comprehensive explorations of nanostructured carrageenan as a drug carrier, gellan gum nanoparticles in drug delivery, and guar-gum nanoparticles in the delivery of bioactive molecules Practical discussions of protein-based nanoparticles for drug delivery, solid lipid nanoparticles as drug carriers, and pH-responsive nanoparticles in therapy In-depth examinations of stimuli-responsive nano carriers in drug targeting Perfect for pharmaceutical chemists, materials scientists, polymer chemists, life scientists, and medicinal chemists, Nanoengineering of Biomaterials: Drug Delivery and Biomedical Applications is also an indispensable resource for biologists and bioengineers seeking a one-stop reference on the transferability of materials chemistry and nanotechnology to biomedicine.
| Author | : Ali Demir Sezer |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 400 |
| Release | : 2016-02-10 |
| Genre | : Medical |
| ISBN | : 9535122479 |
This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.
| Author | : K. L. Mittal |
| Publisher | : John Wiley & Sons |
| Total Pages | : 423 |
| Release | : 2020-05-12 |
| Genre | : Technology & Engineering |
| ISBN | : 1119640253 |
This important and unique book comprises 12 chapters divided into three parts examining the fundamental aspects, bioadhesive formulations, and drug delivery applications. Understanding the phenomenon of bioadhesion i.e. its theories or mechanism(s) are of critical importance in developing optimum bioadhesive polymers (used in bioadhesives). Such bioadhesive polymers are the key for exhibiting the process of bioadhesion, controlled/sustained release of drugs, and drug targeting. The use of bioadhesives restricts the delivery system to the site of interest and thus offers a useful and efficient technique for targeting a drug to the desired location for a prolonged duration. This book addresses the various relevant aspects of bioadhesives in drug delivery in an easily accessible and unified manner. The book containing 12 chapters written by eminent researchers from many parts of the globe is divided into three parts: Part 1: Fundamental Aspects; Part 2: Bioadhesive Formulations; Part 3: Drug Delivery Applications. The topics covered include: Theories and mechanisms of bioadhesion; bioadhesive polymers for drug delivery applications; methods for characterization of bioadhesiveness of drug delivery systems; bioadhesive films and drug delivery applications; bioadhesive nanoparticles; bioadhesive hydrogels and applications; ocular biodhesive drug delivery systems; buccal bioadhesive drug delivery systems; gastrointestinal bioadhesive drug delivery systems; nasal bioadhesive drug delivery systems; vaginal drug delivery systems; pulmonary bioadhesive drug delivery systems.
| Author | : Muhammad Raza Shah |
| Publisher | : Elsevier |
| Total Pages | : 272 |
| Release | : 2022-04-08 |
| Genre | : Technology & Engineering |
| ISBN | : 012821094X |
Organ-specific drug delivery is aimed at achieving increased concentration of therapeutic molecules at target sites with minimum side effects on other healthy tissues. Similarly, drug-specific delivery to some vital organs, such as the brain, lungs, heart and kidneys remains a challenging task for the formulation scientists. Oral delivery of most of the commercially available life-saving drugs has also been impeded by various physio-chemical and biological barriers. These advancements in nanotechnology have led to the development of various pharmaceutical nanocarriers.Nanocarriers for Organ-Specific and Localized Drug Delivery summarizes targeted drug delivery systems and approaches to the major organs of the body. The book shows how drugs can be specifically targeted to the pathological area within an organ in a viable way. Employing pharmaceutical nanocarriers for drug delivery targeted to specific organs of the body requires a comprehensive knowledge of the disease site's pathophysiology as well as physical, chemical and pharmaceutical techniques for modification or functionalization of the nanocarriers.Combining theoretical principles and practical applications of various nanocarriers for organ-specific drug delivery, this is an important reference source for all those seeking to increase their understanding of how pharmaceutical nanocarriers are being used to create more efficient drug delivery systems. - Outlines the underlying principles for the design of advanced pharmaceutical nanocarriers for organ specific drug delivery - Includes guidance on how to exploit the pathophysiology and microenvironment of the diseased sites for targeted drug delivery - Assesses the major challenges for creating pharmaceutical nanocarriers on a mass scale
| Author | : James M. Anderson |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 391 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1461327458 |
The evident rapid expansion of scientific work and intense interest in both experimental and clinical aspects of new drug delivery systems provided strong motivation for planning this symposium. In designing the program, speakers were identified for their particular expertise in a wide range of topics such as dermal delivery systems, pro-drugs, oral prolonged release, rate-controlled drug delivery, the pharmacokinetics of drug release systems, the synthesis of polymeric drug carriers and the refinement of drug delivery pumps. Because of the considerable involvement of diverse scientists from laboratories around the world where investigations relevant to the topic are now being pursued, a deliberate effort was made to invite international leaders in the field to share their knowledge and experimental outcomes. Thus, plenary papers and panel discussions were offered by organic chemists, bioengineers, patholo gists, material scientists, physical chemists, and pharmacokineti cists from academic and industrial laboratories in some dozen countries. This book which records the presentations offered at the sym posium covers a broad array of topics ranging from general overviews of the physicochemical concepts and analytical methodology which underpin the refinement of drug delivery systems and the tissue responses associated with the use of such systems through detailed discussions of a variety of current approaches employed in the development of new systems.
| Author | : Ashim K. Mitra |
| Publisher | : Bentham Science Publishers |
| Total Pages | : 301 |
| Release | : 2013-06-26 |
| Genre | : Medical |
| ISBN | : 1608051757 |
A multidisciplinary approach is increasingly being adapted by the Pharmaceutical industry to tackle several challenges in developing efficacious treatment solutions. The field of Ophthalmology is no less different. Treatise on Ocular Drug Delivery is a unique collection of information put together by various experts in the field. One of the major goals behind this volume is to link clinical information with the current strategies employed in ocular drug delivery. This monograph covers a range of topics on ocular pharmacology. Chapters in the e-book cover several aspects of drug delivery research such as the biochemical background of specific eye diseases, challenges for ocular drug delivery, the role of influx and efflux transporters, novel drug delivery systems, pharmacokinetics, regulatory aspects, and patenting opportunities for researchers. This E-Book would serve as a suitable reference for pharmacy graduates, medical students, professional scientists and ophthalmic clinicians in academic and industrial laboratories.
