Decoding The Human Genome An Overview
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| Author | : Nicky Huys |
| Publisher | : Nicky Huys |
| Total Pages | : 138 |
| Release | : 2023-12-16 |
| Genre | : Science |
| ISBN | : |
"Decoding the Human Genome: An Overview" provides a comprehensive exploration of the groundbreaking advancements in genomics and their impact on understanding the intricacies of human DNA. From the historical milestones in genome sequencing to the latest breakthroughs in personalized medicine, this book offers a clear and accessible overview of the complex world of genetics. Readers will delve into the significance of genetic variation, the role of gene expression, and the implications for addressing genetic disorders. With a focus on the potential applications in healthcare and research, this book serves as an essential guide to the fundamental principles and cutting-edge developments in decoding the human genome.
| Author | : |
| Publisher | : |
| Total Pages | : 68 |
| Release | : |
| Genre | : |
| ISBN | : 0761354891 |
| Author | : Karen Gunnison Ballen |
| Publisher | : Twenty-First Century Books |
| Total Pages | : 68 |
| Release | : 2012-08-01 |
| Genre | : Young Adult Nonfiction |
| ISBN | : 1467701424 |
In the mid-1980s, some geneticists proposed a daring project to sequence the human genome. That meant figuring out the exact order of the three billion chemical pairs that make up human DNA. Sequencing the human genome could help scientists understand how our bodies work and help doctors diagnose, treat, and prevent certain diseases. The Human Genome Project launched in 1990, with scientists around the world collaborating on the research. They worked slowly and methodically, trying to produce the most accurate information possible. By 1991 one of these scientists, Craig Venter, became fed up with the HGP's slow pace. He challenged the HGP to move faster and started his own company to compete with the HGP. Racing neck and neck, the two organizations reached their goal years ahead of schedule. But the challenge also led to a bitter public argument, especially over who could use the sequence and how. This book reveals how ambition, persistence, ego, greed, and principle combined—often with explosive results—in the quest to decode our DNA.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 128 |
| Release | : 1988-01-01 |
| Genre | : Science |
| ISBN | : 0309038405 |
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
| Author | : Kevin Alexander Boon |
| Publisher | : Enslow Publishing |
| Total Pages | : 136 |
| Release | : 2002 |
| Genre | : Juvenile Nonfiction |
| ISBN | : |
Discusses genes, genetics, and the legal and ethical issues involved in mapping DNA in the human body.
| Author | : Kevin Davies |
| Publisher | : JHU Press |
| Total Pages | : 358 |
| Release | : 2002-10 |
| Genre | : Medical |
| ISBN | : 9780801871405 |
This newly updated edition sheds light on the secrets of the sequence, highlighting the myriad ways in which genomics will impact human health for generations to come.
| Author | : J. Craig Venter |
| Publisher | : Penguin |
| Total Pages | : 400 |
| Release | : 2007-10-18 |
| Genre | : Biography & Autobiography |
| ISBN | : 1101202564 |
The triumphant memoir of the man behind one of the greatest feats in scientific history Of all the scientific achievements of the past century, perhaps none can match the deciphering of the human genetic code, both for its technical brilliance and for its implications for our future. In A Life Decoded, J. Craig Venter traces his rise from an uninspired student to one of the most fascinating and controversial figures in science today. Here, Venter relates the unparalleled drama of the quest to decode the human genome?a goal he predicted he could achieve years earlier and more cheaply than the government-sponsored Human Genome Project, and one that he fulfilled in 2001. A thrilling story of detection, A Life Decoded is also a revealing, and often troubling, look at how science is practiced today.
| Author | : Nicholas Wade |
| Publisher | : Simon and Schuster |
| Total Pages | : 209 |
| Release | : 2002-03-02 |
| Genre | : Science |
| ISBN | : 074321739X |
With the decoding of the human genome, researchers can now read the script in which evolution has written the program for the design and operation of the human body. A new generation of medical treatments is at hand. Researchers are developing therapies so powerful that there is now no evident obstacle to the ancient goal of conquering most major diseases. Nicholas Wade has covered the sequencing of the genome, as well as other health and science stories, for The New York Times, in the course of which he has interviewed many of the principal researchers in the field. In this book he describes what the genome means for the health of present and future generations. Someday soon physicians will have access to DNA chips that, from a drop of blood, will screen a person's genes for all the diseases to which he or she may be genetically vulnerable. From full knowledge of the instruction manual of the human body, provided by the genome, pharmaceutical companies hope to develop a new generation of sophisticated drugs; one of the first genome-derived drugs is already undergoing clinical trials. Another vital tool will be regenerative medicine, a new kind of therapy in which new organs and tissues will be grown from a patient's own cells to replace those that are old or diseased. With the help of DNA chips, medical researchers will soon be able to diagnose diseases such as cancer much more precisely and to tailor specific treatments for each patient. Individualized medicine will also become an important part of the pharmaceutical world. Many drugs will be prescribed based on information from DNA chips that identify which of a range of drugs is best for each patient, as well as which drugs are likely to cause side effects. The medicine of the post-genomic era will be customized for a patient's genetic make-up, providing treatments based on a precise understanding of the mechanism of disease. Life Script describes a future in which good health, even perfect health, may become the standard for everyone -- at every age.
| Author | : Robert DeSalle |
| Publisher | : John Wiley & Sons |
| Total Pages | : 280 |
| Release | : 2020-01-27 |
| Genre | : Science |
| ISBN | : 1118750314 |
The popular introduction to the genomic revolution for non-scientists—the revised and updated new edition Welcome to the Genome is an accessible, up-to-date introduction to genomics—the interdisciplinary field of biology focused on the structure, function, evolution, mapping, and editing of an organism's complete set of DNA. Written for non-experts, this user-friendly book explains how genomes are sequenced and explores the discoveries and challenges of this revolutionary technology. Genomics is a mixture of many fields, including not only biology, engineering, computer science, and mathematics, but also social sciences and humanities. This unique guide addresses both the science of genomics and the ethical, moral, and social questions that rise from the technology. There have been many exciting developments in genomics since this book's first publication. Accordingly, the second edition of Welcome to the Genome offers substantial new and updated content to reflect recent major advances in genome-level sequencing and analysis, and demonstrates the vast increase in biological knowledge over the past decade. New sections cover next-generation technologies such as Illumina and PacBio sequencing, while expanded chapters discuss controversial ethical and philosophical issues raised by genomic technology, such as direct-to-consumer genetic testing. An essential resource for understanding the still-evolving genomic revolution, this book: Introduces non-scientists to basic molecular principles and illustrates how they are shaping the genomic revolution in medicine, biology, and conservation biology Explores a wide range of topics within the field such as genetic diversity, genome structure, genetic cloning, forensic genetics, and more Includes full-color illustrations and topical examples Presents material in an accessible, user-friendly style, requiring no expertise in genomics Discusses past discoveries, current research, and future possibilities in the field Sponsored by the American Museum of Natural History, Welcome to the Genome: A User's Guide to the Genetic Past, Present, and Future is a must-read book for anyone interested in the scientific foundation for understanding the development and evolutionary heritage of all life.
| Author | : John F. Atkins |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 473 |
| Release | : 2010-03-10 |
| Genre | : Science |
| ISBN | : 0387893822 |
The literature on recoding is scattered, so this superb book ?lls a need by prov- ing up-to-date, comprehensive, authoritative reviews of the many kinds of recoding phenomena. Between 1961 and 1966 my colleagues and I deciphered the genetic code in Escherichia coli and showed that the genetic code is the same in E. coli, Xenopus laevis, and guinea pig tissues. These results showed that the code has been c- served during evolution and strongly suggested that the code appeared very early during biological evolution, that all forms of life on earth descended from a c- mon ancestor, and thus that all forms of life on this planet are related to one another. The problem of biological time was solved by encoding information in DNA and retrieving the information for each new generation, for it is easier to make a new organism than it is to repair an aging, malfunctioning one. Subsequently, small modi?cations of the standard genetic code were found in certain organisms and in mitochondria. Mitochondrial DNA only encodes about 10–13 proteins, so some modi?cations of the genetic code are tolerated that pr- ably would be lethal if applied to the thousands of kinds of proteins encoded by genomic DNA.
