Guidelines on Hepatitis B and C Testing

Guidelines on Hepatitis B and C Testing
Author: World Health Organization
Publisher: World Health Organization
Total Pages: 0
Release: 2017
Genre: Medical
ISBN: 9789241549981

Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to receive the necessary care and treatment to prevent or delay progression of liver disease. Testing also provides an opportunity to link people to interventions to reduce transmission, through counselling on risk behaviors and provision of prevention commodities (such as sterile needles and syringes) and hepatitis B vaccination. These are the first WHO guidelines on testing for chronic HBV and HCV infection and complement published guidance by WHO on the prevention, care and treatment of chronic hepatitis C and hepatitis B infection. These guidelines outline the public health approach to strengthening and expanding current testing practices for HBV and HCV, and are intended for use across age groups and populations.

Eliminating the Public Health Problem of Hepatitis B and C in the United States

Eliminating the Public Health Problem of Hepatitis B and C in the United States
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 187
Release: 2016-06-01
Genre: Medical
ISBN: 0309438020

Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the first of two, examines the feasibility of hepatitis B and C elimination in the United States and identifies critical success factors. The phase two report will outline a strategy for meeting the elimination goals discussed in this report.

Recommendations and guidance on hepatitis C virus self-testing

Recommendations and guidance on hepatitis C virus self-testing
Author: World Health Organization
Publisher: World Health Organization
Total Pages: 32
Release: 2021-07-15
Genre: Medical
ISBN: 924003112X

WHO has set a global goal to eliminate HCV as a public health problem by 2030. WHO estimates that 58 million people had chronic hepatitis C virus (HCV) infection globally in 2019, and less than a quarter of them were diagnosed. New and innovative approaches are needed to accelerate progress toward the HCV elimination targets. Self-testing is one such approach. These guidelines provide a new recommendation and guidance on HCV self-testing to complement existing HCV testing services in countries. These guidelines also highlight operational considerations to support strategic implementation and scale up of HCV self-testing.

Hepatitis and Liver Cancer

Hepatitis and Liver Cancer
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 252
Release: 2010-04-23
Genre: Medical
ISBN: 0309153689

The global epidemic of hepatitis B and C is a serious public health problem. Hepatitis B and C are the major causes of chronic liver disease and liver cancer in the world. In the next 10 years, 150,000 people in the United States will die from liver disease or liver cancer associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Today, between 800,000 and 1.4 million people in the United States have chronic hepatitis B and between 2.7 and 3.9 million have chronic hepatitis C. People most at risk for hepatitis B and C often are the least likely to have access to medical services. Reducing the rates of illness and death associated with these diseases will require greater awareness and knowledge among health care workers, improved identification of at-risk people, and improved access to medical care. Hepatitis B is a vaccine-preventable disease. Although federal public health officials recommend that all newborns, children, and at-risk adults receive the vaccine, about 46,000 new acute cases of the HBV infection emerge each year, including 1,000 in infants who acquire the infection during birth from their HBV-positive mothers. Unfortunately, there is no vaccine for hepatitis C, which is transmitted by direct exposure to infectious blood. Hepatitis and Liver Cancer identifies missed opportunities related to the prevention and control of HBV and HCV infections. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. It identifies priorities for research, policy, and action geared toward federal, state, and local public health officials, stakeholder, and advocacy groups and professional organizations.

Decision Making in Health and Medicine

Decision Making in Health and Medicine
Author: M. G. Myriam Hunink
Publisher: Cambridge University Press
Total Pages: 447
Release: 2014-10-16
Genre: Education
ISBN: 1107690471

A guide for everyone involved in medical decision making to plot a clear course through complex and conflicting benefits and risks.

Chronic Hepatitis C Virus

Chronic Hepatitis C Virus
Author: Mitchell L. Shiffman
Publisher: Springer Science & Business Media
Total Pages: 333
Release: 2011-11-17
Genre: Medical
ISBN: 1461411920

Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future documents the monumental advances that have been made in our understanding of chronic HCV during the past decade. The first section reviews the natural history of chronic HCV, how this virus can affect other organs in addition to the liver, and whether treating chronic HCV alters the natural history of this disease. Section 2 reviews the advances that have been made in the treatment of chronic HCV during the past decade with interferon based therapy. Separate chapters on response guided therapy and how to manage the adverse events associated with these medications provide the physician with the concepts required to more effectively treat chronic HCV now and in the future. As the genetics of virologic response have recently been elucidated, a chapter is devoted to helping the clinician understand how genes that modulate disease processes and their treatment are identified and utilized in clinical care. Section 3 deals with the future of HCV treatment and specific inhibitors of HCV. Specific chapters explain how targets for drugs are identified and how drugs are then developed and tested; how mutations of HCV develop and how anti-viral agents will affect this process; the most up to date data regarding the treatment of chronic HCV with peginterferon, ribavirin and anti-viral agents; and the potential to treat chronic HCV with just oral anti-viral agents and without peginterferon and ribavirin in the future. The final section of this book covers issues related to liver transplantation in patients with chronic HCV. Separate chapters review the natural history of chronic HCV in liver transplant recipients and the impact of utilizing HCV positive donors. The volume concludes with chapters that cover the treatment of chronic HCV both prior to and after liver transplantation with potent anti-viral agents. Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future is a valuable resource for all physicians caring for patients with chronic HCV.

Hepatitis B and C

Hepatitis B and C
Author: Thierry Poynard
Publisher: CRC Press
Total Pages: 176
Release: 2004-08-25
Genre: Medical
ISBN: 0203357183

Chronic hepatitis B and C affect 520 million people worldwide, and are a major cause of chronic liver disease and of mortality, despite the efficacy of the vaccine. Hepatitis B and C: Management and Treatment second edition provides a practical explanation of the natural history and management of the disease, and examines the benefits of the most recent drugs, and their effects, whether used in isolation or as part of a combination therapy. This second edition expands the coverage of treatment of various difficult-to-treat patients and will be a welcome guide to the physician in both clinical decision-making and in explaining the benefits and side-effects to the patient.

Hepatitis C: Care and Treatment

Hepatitis C: Care and Treatment
Author: Angelos Hatzakis
Publisher: Springer Nature
Total Pages: 219
Release: 2021-05-10
Genre: Medical
ISBN: 3030677621

This volume provides the reader with a detailed overview of the current state-of-the art approach of Hepatitis C management. It reviews the course of action in handling of chronic Hepatitis C patients with various HCV genotypes and treats special cases such as acute hepatitis, transplant and renal patients as well as people who inject drugs. The two volume work on Hepatitis C introduces to the topic by reviewing virology, diagnosis, epidemiology, prevention, management and elimination of HCV. The book provides a valuable source at full length for researchers and clinicians working on Hepatitis C.

Decision Making in Medicine

Decision Making in Medicine
Author: Stuart B. Mushlin
Publisher: Elsevier Health Sciences
Total Pages: 754
Release: 2009-10-27
Genre: Medical
ISBN: 0323041078

This popular reference facilitates diagnostic and therapeutic decision making for a wide range of common and often complex problems faced in outpatient and inpatient medicine. Comprehensive algorithmic decision trees guide you through more than 245 disorders organized by sign, symptom, problem, or laboratory abnormality. The brief text accompanying each algorithm explains the key steps of the decision making process, giving you the clear, clinical guidelines you need to successfully manage even your toughest cases. An algorithmic format makes it easy to apply the practical, decision-making approaches used by seasoned clinicians in daily practice. Comprehensive coverage of general and internal medicine helps you successfully diagnose and manage a full range of diseases and disorders related to women's health, emergency medicine, urology, behavioral medicine, pharmacology, and much more. A Table of Contents arranged by organ system helps you to quickly and easily zero in on the information you need. More than a dozen new topics focus on the key diseases and disorders encountered in daily practice. Fully updated decision trees guide you through the latest diagnostic and management guidelines.