The Heart in Rheumatic, Autoimmune and Inflammatory Diseases

The Heart in Rheumatic, Autoimmune and Inflammatory Diseases
Author: Udi Nussinovitch
Publisher: Academic Press
Total Pages: 768
Release: 2017-02-10
Genre: Medical
ISBN: 0128032685

The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe. - A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. - Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. - Presents an up-to-date "level of evidence and "strengths of recommendations for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.

Vaccines for the 21st Century

Vaccines for the 21st Century
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 472
Release: 2001-02-21
Genre: Medical
ISBN: 0309174988

Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.

Paediatric Rheumatology

Paediatric Rheumatology
Author: Helen E. Foster
Publisher: OUP Oxford
Total Pages: 416
Release: 2012-06-14
Genre: Medical
ISBN: 0191645338

Paediatric Rheumatology is an indispensible resource for the identification and management of specific rheumatological disorders. As well as covering common and rare rheumatological problems, there are also chapters on investigations and emergencies, designed for quick reference. The handbook includes dedicated topics on systemic diseases affecting rheumatology; the relevant clinical guidelines and information needed for a rheumatologist to successfully management a young patient; and, a coloured section for guidance on rash-related investigations. Paediatric Rheumatology is also fully endorsed by the British Society for Paediatric and Adolescent Rheumatology and the UK Paediatric Rheumatology Clinical Studies Group.

A Clinician's Pearls & Myths in Rheumatology

A Clinician's Pearls & Myths in Rheumatology
Author: John H. Stone
Publisher: Springer Science & Business Media
Total Pages: 489
Release: 2009-10-03
Genre: Medical
ISBN: 1848009348

Important strides have been made in understanding the pathophysiologic basis of many inflammatory conditions in recent years, but rheumatology remains a discipline in which diagnosis is rooted in the medical history skillfully extracted from the patient, the careful physical examination, and the discriminating use of laboratory tests and imaging. Moreover, selection of the most appropriate therapy for patients with rheumatic diseases also remains heavily reliant upon clinical experience. Medical disciplines such as rheumatology that depend significantly upon clinical wisdom are prone to the development of systems of ‘Pearls’ and ‘Myths,’ related to the diseases they call their own, a ‘Pearl’ being a nugget of truth about the diagnosis or treatment of a particular disease that has been gained by dint of clinical experience and a ‘Myth’ being a commonly held belief that influences the practice of many clinicians – but is false. This book will pool together the clinical wisdom of seasoned, expert rheumatologists who participate in the care of patients with autoimmune diseases, systemic inflammatory disorders, and all other rheumatic conditions.

Pulmonary Manifestations of Rheumatic Disease

Pulmonary Manifestations of Rheumatic Disease
Author: Paul F. Dellaripa
Publisher: Springer
Total Pages: 227
Release: 2014-05-23
Genre: Medical
ISBN: 1493907700

The spectrum of systemic rheumatologic disease (often termed connective tissue disease) is characterized by autoimmune-mediated organ dysfunction, and the lungs are a frequent target. There are numerous pulmonary manifestations associated with connective tissue diseases, and all patients with rheumatologic disease are at risk of developing associated lung disease. Pulmonary Manifestations of Rheumatic Disease covers the comprehensive management of rheumatologic lung disease, which requires a multi-disciplinary approach and is optimized by active engagement by rheumatologists working closely with pulmonologists and other specialists. The book offers a practical reference using a case-based approach for practicing clinicians in the ongoing assessment and understanding of rheumatologic lung disease, and presents the science and pathophysiology underlying rheumatologic lung diseases. The first text of its kind specifically dedicated to describe diverse, commonplace, and challenging aspects of rheumatologic lung diseases, Pulmonary Manifestations of Rheumatic Disease serves as an invaluable tool for the practicing clinician.

Early Rheumatoid Arthritis

Early Rheumatoid Arthritis
Author: Paul Emery
Publisher:
Total Pages: 0
Release: 2005
Genre: Rheumatoid arthritis
ISBN: 9781416027676

This issue covers the latest developments in the understanding of rheumatoid arthritis at the early stage. Treatments such as with newer biologic agents and conventional disease-modifying antirheumatic drugs are reviewed. Also included are articles on imaging modalities as a means of identifying those in the early stages and monitoring response to treatment.

Death by Rheumatoid Arthritis

Death by Rheumatoid Arthritis
Author: Carla Jones
Publisher: CreateSpace
Total Pages: 48
Release: 2013-09
Genre: Health & Fitness
ISBN: 9781491041987

More than a million Americans suffer from rheumatoid arthritis. The numbers of deaths from this disease continues to climb each year. Late diagnosis and treatment for arthritis related, cervical spine deterioration, is one reason for some of these deaths. Celia Veno, a Bucks County retired woman and mother was one of those fatalities.Celia Veno, a woman in her 70's, began, experiencing mysterious migraine-like headaches and atrophy. After her general doctor and neurologist failed to determine the cause of these symptoms, a new rheumatologist was called upon. He immediately diagnosed from a previous cervical spine x-ray, that she had advanced spinal cord syndrome. Unfortunately, the findings came critically late. She died two months later. Eighty-six percent of people with rheumatoid arthritis have the disease in their neck. (cervical spine). “Death by Rheumatoid Arthritis”, lists signs and symptoms of spinal instability, due to advancement of the disease.Carla Jones is dedicated to bringing awareness to the undisputed fact, that anyone can die from complications related to rheumatoid arthritis, and to promote early detection of cervical collar damage, for those with the disease.

Oxford Textbook of Rheumatoid Arthritis

Oxford Textbook of Rheumatoid Arthritis
Author: David L. Scott
Publisher: Oxford University Press
Total Pages: 576
Release: 2020-09-18
Genre: Medical
ISBN: 0192567101

This brand new textbook of rheumatoid arthritis (RA) is an important addition to the Oxford Textbooks in Rheumatology series, and provides a comprehensive overview of both the scientific and clinical aspects of the disease. Divided into eight sections - from the history, diagnosis, and epidemiology of the disease, through the pathogenesis, clinical presentation, and assessment to treatments and management strategies, both drug- and non-drug based - each chapter is written by leading clinicians and scientists in the field to deliver a contemporary view of RA. During the past two decades there have been revolutionary changes in the understanding and management of rheumatoid arthritis, in particular the development of biological treatments. This has had wide-ranging effects on almost all aspects of treatment, from effectiveness and intensity to the nature and the cost. Providing a comprehensive account of the modern ideas about the disease, the Oxford Textbook of Rheumatoid Arthritis is a key new addition to the literature, with each chapter providing a detailed background, key recent advances, and areas of doubt and future developments. Featuring over 170 photographs, radiological images, and clinical charts to aid both diagnosis and illustrate the rationale behind key scientific studies, this new title will prove an indispensable resource for specialist rheumatologists, trainees in rheumatology, and other members of the multi-disciplinary team.

Skills in Rheumatology

Skills in Rheumatology
Author: Hani Almoallim
Publisher: Springer Nature
Total Pages: 562
Release: 2021-01-05
Genre: Medical
ISBN: 9811583234

This Open Access book presents practical approaches to managing patients affected by various rheumatological diseases, allowing readers to gain a better understanding of the various clinical expressions and problems experienced by these patients. Discussing rheumatology from an organ systems perspective, it highlights the importance ofdetailed musculoskeletal examinations when treating patients affected by rheumatological diseases. The book first explores the latest diagnostic approaches and offers key tips for accurate musculoskeletal examinations before addressing the various treatment modalities, with a particular focus on the most common joints involved in rheumatoid arthritis: the wrists and the metacarpophalangeal joints (2nd and 3rd). Featuring easy-to-understand flow diagrams and explaining the common medical problems associated with rheumatic disease, such as shortness of breath and anemia, it is not only a valuable resource to rheumatologists, but will also appeal to medical students, junior residents, and primary healthcare physicians.

Spine Surgery Basics

Spine Surgery Basics
Author: Vikas V. Patel
Publisher: Springer Science & Business Media
Total Pages: 565
Release: 2013-09-11
Genre: Medical
ISBN: 3642341268

Spine surgery has increasingly become a surgical field of its own, with a distinct body of knowledge. This easy-to-use book, written by acknowledged experts, is designed to meet the practical needs of the novice and the busy resident by providing essential information on spine pathology, diagnostic evaluation, surgical procedures, and other treatments. After an opening general section, degenerative spinal disease, pediatric spine conditions, spine trauma, spine tumors, infections, inflammatory disorders, and metabolic conditions are all discussed in more depth. Alongside description and evaluation of surgical options, important background information is included on pathology, presentation, diagnosis, and nonsurgical treatments. Potential complications of surgery are also carefully considered. Spine Surgery Basics will be an invaluable aid for all who are embarking on a career in spinal surgery or require a ready reference that can be consulted during everyday practice.