Cytoskeletal-membrane Interactions and Signal Transduction
Author | : Pam Cowin |
Publisher | : R G Landes Company |
Total Pages | : 237 |
Release | : 1997-01-01 |
Genre | : Science |
ISBN | : 9781570594557 |
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Author | : Pam Cowin |
Publisher | : R G Landes Company |
Total Pages | : 237 |
Release | : 1997-01-01 |
Genre | : Science |
ISBN | : 9781570594557 |
Author | : Pam Cowin |
Publisher | : Landes Bioscience |
Total Pages | : 268 |
Release | : 1997 |
Genre | : Medical |
ISBN | : |
Author | : |
Publisher | : Academic Press |
Total Pages | : 449 |
Release | : 1996-11-21 |
Genre | : Science |
ISBN | : 0080585140 |
The plasma membrane acts as both a boundary and a site of exchange between the outside and the inside of a cell. The cytoskeleton plays essential roles in delineating membrane protein distributions, in defining structural and functional domains in the plasma membrane, and in regulating membrane protein, and ultimately, cell function. This volume reviews the regulation of membrane protein distribution, organization, and function at the plasma membrane by the cytoskeleton. Discussions also include the roles of cytoskeleton in the structural and functional organization of membranes and membrane proteins with emphasis on key problems, the current status of understanding, experimental approaches, and future directions.
Author | : Kermit L. Carraway |
Publisher | : Springer Science & Business Media |
Total Pages | : 293 |
Release | : 2013-03-09 |
Genre | : Science |
ISBN | : 3662129930 |
This monograph explores the relationships between cell signaling and the cytoplasmic cytoskeleton in fundamental cell processes, thus bridging the gap between two very active aspects of molecular cell biology. It covers the two main - and reciprocal - questions of these relationships: How are structure and function of the cytoskeleton affected by external signals which impinge on the cell? How does the cytoskeleton influence the cellular signaling processes which determine cell behavior?
Author | : Bruce Alberts |
Publisher | : |
Total Pages | : 0 |
Release | : 2002 |
Genre | : Cytology |
ISBN | : 9780815332183 |
Author | : Ryo Sato |
Publisher | : John Wiley & Sons |
Total Pages | : 280 |
Release | : 2008-04-30 |
Genre | : Science |
ISBN | : 0470514213 |
A panel of internationally renowned experts present papers on cell signalling--an area in which there has been recent important advances. Coverage includes the inositol 1, 4, 5-triphosphate receptor, signal-induced phospholipid degradation cascade and protein kinase C activation, cyclic AMP interactions in sustained cellular response, the acetylcholine receptor and much more.
Author | : Clément Thomas |
Publisher | : Frontiers E-books |
Total Pages | : 81 |
Release | : 2014-10-23 |
Genre | : Botany |
ISBN | : 2889193233 |
Various cellular processes underlying plant development and response to environmental cues rely on a dynamic interplay between membranes and the cytoskeleton, e.g. vesicle and organelle trafficking, endocytosis, exocytosis, and signal transduction. In recent years, significant progress in the understanding of such interplay has been achieved and several critical links between membranes and the cytoskeleton have been characterized. As an example, recent work has clarified how auxin promotes the reorganization of cortical actin filaments by the activation of Rho GTPase pathways, and how such reorganization in turn locally modifies endocytosis and/or exocytosis and directs asymmetric distribution of PIN family of auxin transporters. Another recent achievement is the characterization of the Rho- and microtubule-driven mechanism by which the cell wall architecture is established. In particular, the elegant work by Oda and Fukuda (Science 337 p.1333, 2012) provides evidence that secondary wall patterning in xylem vessel primarily relies on two processes: a local activation of the plant Rho GTPase ROP11 and a mutual, MIDD1-mediated, inhibitory interaction between active ROP domains and cortical microtubules. Additional examples include recent genetic evidence that microtubule and actin filament interacting/regulatory proteins, such as MAP65-1 and capping protein, function as transducers of membrane lipid signaling into changes in cytoskeleton dynamics and organization. This Research Topic aims at collecting a comprehensive set of articles dealing with cellular processes involving membrane-cytoskeleton interactions. Its scope extends beyond the specific fields defined by the above examples and includes intracellular trafficking, host-pathogen interactions, response to biotic and abiotic stresses and hormonal regulation of growth. We hope that this Research Topic will also highlight critical questions that need to be addressed in the future. We welcomed Original Research Articles, Technical/Methodological Advances (e.g. analysis of cytoskeleton dynamics close to membranes), Reviews and Mini Reviews that can expand our understanding of how and why membranes and the cytoskeleton interact.
Author | : Kermit Carraway |
Publisher | : OUP Oxford |
Total Pages | : 308 |
Release | : 1999-12-16 |
Genre | : Science |
ISBN | : 0191565997 |
This book provides descriptions of experimental methods in research on the cytoskeleton and its relationships to signaling and cell regulation. Thus, it bridges two active and fertile areas of research. The focus is directed particularly towards methods which take advantage of recent advances in molecular biology, microscopy and immunological assays. A second emphasis is on methods for understanding dynamic changes in cells. A third emphasis is on the formation and turnover of macromolecular and supramolecular complexes, which are so important in driving cell regulation and the behaviour of cytoskeletal elements. A combination of practical advice and detailed protocols should make this book valuable for both novice and experienced workers in these burgeoning fields.
Author | : Society of General Physiologists. Symposium |
Publisher | : Rockefeller Univ. Press |
Total Pages | : 296 |
Release | : 1997 |
Genre | : Science |
ISBN | : 9780874700596 |
Author | : Edward Bittar |
Publisher | : Elsevier |
Total Pages | : 317 |
Release | : 1997-05-12 |
Genre | : Science |
ISBN | : 0080536115 |
It should not come as too much of a surprise that biological membranes are considerably more complex than lipid bilayers. This has been made quite clear by the fluid-mosaic model which considers the cell membrane as a two-dimensional solution of a mosaic of integral membrane proteins and glycoproteins firmly embedded in a fluid lipid bilayer matrix. Such a model has several virtues, chief among which is that it allows membrane components to diffuse in the plane of the membrane and orient asymmetrically across the membrane. The model is also remarkable since it provokes the right sort of questions. Two such examples are: Does membrane fluidity influence enzyme activity? Does cholesterol regulate fluidity? However, it does not go far enough. As it turns out, there is now another version of this model, the so-called post-fluid mosaic model which incorporates two concepts, namely the existence in the membrane of discrete domains in which specific lipid-lipid, lipid-protein and protein-protein interactions occur and ordered regions that are in motion but remain separate from less ordered regions. We must admit that both are intriguing problems and of importance in guiding our thinking as to what the next model might be. We have chosen not to include the subject of membrane transport in the present volume. This obviously represents a break with convention. However, the intention is to have the topic covered subsequent volumes relating to organ systems. It would be right to regard this as an attempt to strengthen the integrated approach to the teaching of medicine.