Cytochrome P450 1991 716 P Il 24 Cm Methods In Enzymology 206
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Cytochrome P450
Author | : Paul R. Ortiz de Montellano |
Publisher | : Springer Science & Business Media |
Total Pages | : 702 |
Release | : 2007-02-05 |
Genre | : Medical |
ISBN | : 0387274472 |
Cytochrome P450: Structure, Mechanism, and Biochemistry, third edition is a revision of a review that summarizes the current state of research in the field of drug metabolism. The emphasis is on structure, mechanism, biochemistry, and regulation. Coverage is interdisciplinary, ranging from bioinorganic chemistry of cytochrome P450 to its relevance in human medicine. Each chapter provides an in-depth review of a given topic, but concentrates on advances of the last 10 years.
Toxicological Profile for Polycyclic Aromatic Hydrocarbons
Author | : |
Publisher | : |
Total Pages | : 500 |
Release | : 1995 |
Genre | : Polycyclic aromatic hydrocarbons |
ISBN | : |
Modern Biooxidation
Author | : Rolf D. Schmid |
Publisher | : John Wiley & Sons |
Total Pages | : 318 |
Release | : 2007-09-24 |
Genre | : Science |
ISBN | : 3527611533 |
Filling a gap in the literature, leading expert editors and top international authors present the field of biooxidation from an academic and industrial point of view, taking many examples from modern pharmaceutical research. Topics range from the application of different monooxygenases to applications in the pharmaceutical industry, making this volume of high interest not only for those working in biotechnology but also for organic synthetic chemists, among others.
Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc
Author | : Institute of Medicine |
Publisher | : National Academies Press |
Total Pages | : 798 |
Release | : 2002-07-19 |
Genre | : Medical |
ISBN | : 0309072905 |
This volume is the newest release in the authoritative series issued by the National Academy of Sciences on dietary reference intakes (DRIs). This series provides recommended intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for individuals based on age and gender. In addition, a new reference intake, the Tolerable Upper Intake Level (UL), has also been established to assist an individual in knowing how much is "too much" of a nutrient. Based on the Institute of Medicine's review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health. The book also: Reviews selected components of food that may influence the bioavailability of these compounds. Develops estimates of dietary intake of these compounds that are compatible with good nutrition throughout the life span and that may decrease risk of chronic disease where data indicate they play a role. Determines Tolerable Upper Intake levels for each nutrient reviewed where adequate scientific data are available in specific population subgroups. Identifies research needed to improve knowledge of the role of these micronutrients in human health. This book will be important to professionals in nutrition research and education.
Monooxygenase, Peroxidase and Peroxygenase Properties and Mechanisms of Cytochrome P450
Author | : Eugene G. Hrycay |
Publisher | : Springer |
Total Pages | : 376 |
Release | : 2015-05-22 |
Genre | : Medical |
ISBN | : 3319160095 |
This book describes in 13 chapters mechanisms of P450 used to monooxygenate substrates via the NAD(P)H/O2 pathway using its peroxidase and peroxygenase functions. P450 also utilizes peroxides, peracids, periodate and iodosobenzene to oxygenate substrates via the shunt pathway. Also described are mechanisms used in the oxidation of pharmaceuticals by CYP3A4; acyl- carbon cleavage by CYP17A1, CYP19A1 and CYP51A1; metabolism of tetrabromodiphenyl ethers and bile acids by CYP2B6 and CYP3A4; metabolism of ω-6 and ω-3 polyunsaturated fatty acids; H2O2-mediated peroxygenation of substrates using substrate misrecognition; P450 oxidative reactions using electrochemical methods; electron transfer to P450 by redox proteins; hydroxylation of 1,8-cineole by P450cin; and peroxygenation by unspecific peroxygenases using H2O2. The topics covered are relevant to P450 researchers, professors and students from a variety of disciplines ranging from pharmacology, toxicology and microbiology to chemistry.
Tolerable upper intake levels for vitamins and minerals
Author | : European Commission. Scientific Committee on Food |
Publisher | : |
Total Pages | : 478 |
Release | : 2006 |
Genre | : Dietary supplements |
ISBN | : 9789291990146 |
Flavin-Dependent Enzymes: Mechanisms, Structures and Applications
Author | : |
Publisher | : Academic Press |
Total Pages | : 568 |
Release | : 2020-09-21 |
Genre | : Science |
ISBN | : 012820138X |
The Enzymes, Volume 47, highlights new advances in the field, with this new volume presenting interesting chapters on The Multipurpose Family of Oxidases, Vanillyl alcohol oxidase, Choline oxidases, Aryl alcohol oxidase, D- and L-amino acid oxidases, Sugar oxidases, Phenolic Compounds hydroxylases, Baeyer-Villiger Monooxygenases, Flavin-dependent halogenases, Flavin-dependent dehalogenases, Styrene Monooxygenases, Bacterial luciferases, Cellobiose Dehydrogenases, Prenylated flavoenzymes, Ene-reductases, Flavoenzymes in Biocatalysis. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in The Enzymes series