Cutaneous Drug Hypersensitivity
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| Author | : Andreas J. Bircher |
| Publisher | : Springer Nature |
| Total Pages | : 346 |
| Release | : 2022-07-09 |
| Genre | : Medical |
| ISBN | : 3030827437 |
This book covers all aspects of hypersensitivity to drugs, providing practical information for non-specialist physicians as well as addressing issues of interest to practitioners in different specialties and presenting the expert knowledge required by specialist allergists and immunologists. The opening, general section discusses basics such as clinical manifestations, histopathology, mechanisms, risk factors, drug hypersensitivity in particular populations, and the full range of diagnostic methods. The second part of the book provides concise information on the most important drug classes and guides the reader on how to proceed when patients present with a suspected reaction. For each drug class, the current level of evidence for use of the different diagnostic tools, including skin tests, provocation tests, and in vitro tests, is clarified, and management options, outlined. The inclusion of helpful tables and algorithms is designed to aid in decision making. Drug hypersensitivity is among the more complex allergological issues, and this book will meet the needs of general practitioners, internists, and specialists.
| Author | : Lars E. French |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 255 |
| Release | : 2012 |
| Genre | : Medical |
| ISBN | : 3805599706 |
An indispensable tool for understanding, diagnosing and managing this common clinical problem The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1-5% for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists.
| Author | : Neil H. Shear |
| Publisher | : Springer |
| Total Pages | : 307 |
| Release | : 2018-10-19 |
| Genre | : Medical |
| ISBN | : 9811314896 |
This resource guides prescribers, pharmacists, and regulators with an update on the recent expansion of basic and clinical knowledge that forms a framework for understanding cutaneous reactions. This understanding will lead, in turn, to better outcomes and decisions in treatment and management, both in the clinic and in the life cycle of drug development. The skin is a common target for adverse drug events and even mild rashes can be part of life-threatening syndromes. Patients and practitioners often face important decisions about therapy after a drug eruption, including treatment, cross-reactivity with future pharmaceuticals, genetic considerations and dealing with long-term sequelae after a reaction. An international team of experts and leaders in the field share their story and insights into the scientific details and relevant clinical context.
| Author | : Werner J. Pichler |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 440 |
| Release | : 2007-01-01 |
| Genre | : Medical |
| ISBN | : 3805582692 |
Approaches the phenomenon of drug hypersensitivity in a comprehensive manner. Besides epidemiological aspects, it addresses the immunological mechanisms underlying these complicated reactions which go far beyond the IgE-mediated drug allergies also considered in this book. The book also covers clinical manifestations and new diagnostic methods, and introduces some recetly established animal models. Many topics are treated from multiple perspectives, and the 33 chapters are thoroughly cross-referenced.
| Author | : David Khan |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 250 |
| Release | : 2017-07-05 |
| Genre | : Medical |
| ISBN | : 0323497071 |
With a focus on improving diagnosis and treatment, Drug Allergy Testing is your new go-to resource for understanding various drug allergies and testing methods, the epidemiology of and economic impact of drug allergies, and new drug and allergy developments. Features a wealth of up-to-date information for allergists, immunologists, and primary care physicians who diagnose and treat patients with drug allergies and hypersensitivity. Covers the basics of drug allergy evaluation and management as well as specific drugs including antibiotics, ASA/NSAIDs, chemotherapeutic agents and monoclonal antibodies.
| Author | : Esen Özkaya |
| Publisher | : Springer |
| Total Pages | : 268 |
| Release | : 2014-11-15 |
| Genre | : Medical |
| ISBN | : 1447165365 |
Adverse cutaneous drug reactions (ACDR) are among the most frequent events in patients receiving drug therapy. Cardiovascular (CV) drugs are an important group of drugs with potential risk of developing ACDR especially in elderly as marketing of more new drugs and their prescription continue to increase. However, like with most other drugs the exact incidence of cutaneous side effects from CV drugs is difficult to estimate due to sporadic reporting. Moreover, a reliable designation of a certain drug as the cause of a certain type of reaction can rarely be made. Apart from the well-known angioedema/urticaria from ACE inhibitors, lichen planus / lichenoid reaction from beta adrenergic blockers and photosensitivity from thiazid diuretics, ACDR from CV drugs might be seen in a wide spectrum extending to rare but life-threatening conditions such as erythroderma, Stevens-Johnson syndrome, toxic epidermal necrolysis or drug hypersensitivity syndrome. In this comprehensive review, the reported types of ACDR to CV drugs will be discussed according to drug class and the type of dermatologic reaction with special emphasize on cross-reactions and the role of patch testing in diagnosis.
| Author | : Mariana C. Castells |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : |
| Release | : 2017-10-06 |
| Genre | : Medical |
| ISBN | : 0323548849 |
This issue of Immunology and Allergy Clinics, guest edited by Mariana Castells, is devoted to Drug Hypersensitivity and Desensitizations. Articles in this issue include: Principles and Practice of Drug Desensitization; Incidence and Prevalence of Drug Hypersensitivity; Drug-Induced Anaphylaxis; Penicillin and Beta Lactam Hypersensitivity; Platins Chemotherapy Hypersensitivity: Prevalence and Management; Monoclonal Antibodies Hypersensitivity: Prevalence and Management; Injectable Drugs and MoAbs Reactions and Management with Desensitization; Delayed Cutaneous Reactions to Antibiotics, Management with Desensitization; Management of Children with Hypersensitivity to Antibiotics and MoAbs; Taxenes Hypersensitivity and Management; Progesterone Autoimmune Dermatitis; Severe Delayed Drug Reaction: Role of Genetics and Viral Infections; andAspirin and NSAIDS Hypersensitivity and Management.
| Author | : Amanda Oakley |
| Publisher | : Scion Publishing Ltd |
| Total Pages | : 438 |
| Release | : 2017-05-06 |
| Genre | : Medical |
| ISBN | : 1911510118 |
A concise overview of the common dermatological conditions most likely to present in general medicine From reviews: "... a perfect solution to the constant struggle that dermatology diagnosis presents to primary care physicians and other providers... This well-formatted book covers a vast array of topics ranging from common to rare skin disorders. The pictures are immensely helpful in the understanding of various skin rashes...." Fam Med 2019;51(5):451–452. “... easy to read and informative. One cannot emphasise enough the quality and comprehensive nature of the photographic content.... As someone who was interested in dermatology even as a medical student my only regret is that this book was not around when I was a student as it would have very adequately guided me into my beloved subspecialty.” Ulster Med J 2017;86(3):1–1. “The introduction outlines dermatological conditions by symptom, morphology and body site, providing an excellent index prior to delving into greater detail in the following chapters. The logical approach and level of detail make this text perfect for medical students, interns/residents, primary care physicians and other specialists who wish to quickly identify differential diagnoses or refresh their knowledge of dermatological conditions.” A Lecturer in Dermatology Dermatology Made Easy is based on the hugely popular DermNet New Zealand website and is designed to help GPs, medical students and dermatologists diagnose skin conditions with confidence. The book starts by providing a series of comprehensive tables, complete with over 500 thumbnail photos, to aid diagnosis according to symptoms, morphology, or body site. Once you have narrowed down the diagnosis, cross-references then guide you to more detailed descriptions, and another 700 photographs, covering: common infections inflammatory rashes non-inflammatory conditions skin lesions Every section provides consistent information on the disorder: who gets it and what causes it? what are the clinical features and does it cause any complications? how do you diagnose it? how do you treat it and how long does it take to resolve? The book concludes with a comprehensive section on further investigations and treatment options. Dermatology Made Easy combines the essential focus of the Made Easy book series with the authority and knowledge base of DermNet New Zealand’s unparalleled resources. Printed in full colour throughout.
| Author | : Brian A. Baldo |
| Publisher | : Springer Nature |
| Total Pages | : 732 |
| Release | : 2020-12-08 |
| Genre | : Medical |
| ISBN | : 3030517403 |
The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships. New content expands to two areas of drug allergy that have recently experienced explosive growth: biological therapies and new targeted chemotherapies. Other new and expanded chapters address antimicrobials; drugs used in anesthesia and surgery; opioids; non-targeted anti-cancer drugs; vaccines; and newly understood reaction mechanisms. This new edition includes photographs of a wide variety of cutaneous manifestations that will be of use to other clinicians as well as allergists and dermatologists. In addition to its wide clinical emphasis, the book’s mechanistic and structure-activity detail will provide valuable background for researchers and investigators in universities, medical research institutes, drug companies, and regulatory agencies. The second edition of Drug Allergy is an essential reference for practitioners across the medical disciplines from specialist clinicians, surgeons, GPs, residents, and medical students to nurses, pharmacists, dentists, and those taking undergraduate and graduate courses in the biomedical sciences.
| Author | : Misha Rosenbach |
| Publisher | : Springer |
| Total Pages | : 373 |
| Release | : 2018-11-03 |
| Genre | : Medical |
| ISBN | : 3319184490 |
Inpatient Dermatology is a concise and portable resource that synthesizes the most essential material to help physicians with recognition, differential diagnosis, work-up, and treatment of dermatologic issues in the hospitalized patient. Complete with hundreds of clinical and pathologic images, this volume is both an inpatient dermatology atlas and a practical guide to day-one, initial work-up, and management plan for common and rare skin diseases that occur in the inpatient setting. Each chapter is a bulleted, easy-to-read reference that focuses on one specific inpatient dermatologic condition, with carefully curated clinical photographs and corresponding histopathologic images to aid readers in developing clinical-pathologic correlation for the dermatologic diseases encountered in the hospital. Before each subsection the editors share diagnostic pearls, explaining their approach to these challenging conditions. This book is structured to be useful to physicians, residents, and medical students. It spans dermatology, emergency medicine, internal medicine, infectious disease, and rheumatology. Inpatient Dermatology is the go-to guide for hospital-based skin diseases, making even the most complex inpatient dermatologic issues approachable and understandable for any clinician.
