Proteomic Methods in Neuropsychiatric Research

Proteomic Methods in Neuropsychiatric Research
Author: Paul C. Guest
Publisher: Springer
Total Pages: 0
Release: 2017-04-04
Genre: Science
ISBN: 9783319524788

Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by step instructions on how to carry out each of the protocols. It is also of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner.

Be Your Own Bodybuilding Coach

Be Your Own Bodybuilding Coach
Author: Scott Walter Stevenson
Publisher:
Total Pages: 440
Release: 2018-08-20
Genre:
ISBN: 9780990471813

This book is a strategic plan and resource manual covering bodybuilding from A-Z: In-depth perspective on goal setting, dietary manipulations, nutritional supplementation, posing/presentation, and dozens of other topics including peak week, "metabolic damage," training after 40 and being a critical-thinking bodybuilder. >2000 scientific references.

National Bicycling and Walking Study

National Bicycling and Walking Study
Author:
Publisher:
Total Pages: 110
Release: 1991
Genre: Bicycle trails
ISBN:

The fiscal year 1991 U.S. DOT Appropriations Act directed the Secretary of Transportation to conduct a National Bicycling and Walking Study. The five objectives of the study as specified in the Act were to: (1) Determine the current levels of bicycling and walking and identify reasons they are not better used as means of transportation; (2) Develop a plan for the increased use and enhanced safety of these modes and identify the resources necessary to implement and achieve this plan; (3) Determine the full costs and benefits of promoting bicycling and walking in urban and suburban areas; (4) Review and evaluate the success of promotion programs around the world to determine their applicability to the role required of the U.S. DOT to implement a successful program; and (5) Develop an action plan, including timetable and budget, for implementation of such Federal transportation policy. The purpose of this Interim Report is to document progress in addressing these five objectives. In dealing with each objective, this report summarizes available information, discusses what additional information is required, and outlines the approach to be used in collecting it.

Revitalize - 9Marks Journal

Revitalize - 9Marks Journal
Author: Jonathan Leeman
Publisher:
Total Pages: 52
Release: 2016-09-06
Genre:
ISBN: 9781537163529

9Marks Journal: RevitalizeChurch planting is a great thing, and there's no need to take anything away from it. But there should also be a default setting in a Christian's heart that always longs to see dying churches revitalized. It's not like the debate in your head about whether to fork over $2000 to the mechanic to fix your clunker of a car or to just buy a new one. It's more like a decision about whether to walk away from a dear but difficult relationship. Our hearts should never want to do that, even if once in a great while we must.Start with Andy Davis' remarkable story of reforming one church, and you'll find something that feels strangely like it's from the Bible, as if Andy were only doing what the apostles did. Then let the biblical burden of Bobby Jamieson's article sit on you. I'm serious. You just might find some new light bulbs turning on. Matt Schmucker's and Mike McKinley's articles then round out the apologetic by offering crisp statements for why churches and pastors should pursue the work of revitalizing.If you are a pastor, keep reading into the next section, where Jeramie Rinne, Greg Gilbert, John Folmar, J. D. Greear, and Brian Croft offer valuable and practical wisdom on how to proceed with the work of reform.Could it be that church revitalization does not loom as large in the modern evangelical mindset as it did in Jesus' and the apostles'? Before you answer that question, if nothing else, read Bobby's article. You just might wonder if we've missed something basic.

International Plumbing Code

International Plumbing Code
Author: Cengage Learning
Publisher: Cengage Learning
Total Pages: 0
Release: 2009-02-24
Genre: Building laws
ISBN: 9781580017329

"Now includes International Private Sewage Disposal Code"--Cover.

The White Scourge

The White Scourge
Author: Neil Foley
Publisher: Univ of California Press
Total Pages: 370
Release: 1998-01-02
Genre: History
ISBN: 9780520918528

In a book that fundamentally challenges our understanding of race in the United States, Neil Foley unravels the complex history of ethnicity in the cotton culture of central Texas. This engrossing narrative, spanning the period from the Civil War through the collapse of tenant farming in the early 1940s, bridges the intellectual chasm between African American and Southern history on one hand and Chicano and Southwestern history on the other. The White Scourge describes a unique borderlands region, where the cultures of the South, West, and Mexico overlap, to provide a deeper understanding of the process of identity formation and to challenge the binary opposition between "black" and "white" that often dominates discussions of American race relations. In Texas, which by 1890 had become the nation's leading cotton-producing state, the presence of Mexican sharecroppers and farm workers complicated the black-white dyad that shaped rural labor relations in the South. With the transformation of agrarian society into corporate agribusiness, white racial identity began to fracture along class lines, further complicating categories of identity. Foley explores the "fringe of whiteness," an ethno-racial borderlands comprising Mexicans, African Americans, and poor whites, to trace shifting ideologies and power relations. By showing how many different ethnic groups are defined in relation to "whiteness," Foley redefines white racial identity as not simply a pinnacle of status but the complex racial, social, and economic matrix in which power and privilege are shared. Foley skillfully weaves archival material with oral history interviews, providing a richly detailed view of everyday life in the Texas cotton culture. Addressing the ways in which historical categories affect the lives of ordinary people, The White Scourge tells the broader story of racial identity in America; at the same time it paints an evocative picture of a unique American region. This truly multiracial narrative touches on many issues central to our understanding of American history: labor and the role of unions, gender roles and their relation to ethnicity, the demise of agrarian whiteness, and the Mexican-American experience.

Letters at 3am

Letters at 3am
Author: Michael Ventura
Publisher: Spring Publications
Total Pages: 264
Release: 1993
Genre: History
ISBN:

"I'd rather have one or two of his whiplashing essays in my hands than almost any tome of philosophy". -- Thomas Moore