The global population is increasing at a much faster pace than an increase in the genetic gain for food production by plant breeding. Therefore, we must find ways or methods to improve our food production if we are to ensure food security for all. This special edition is about the novel ways or methodologies that crop or plant scientists are working on to improve crop yield. This could fall under the physiological, biochemical, molecular, or even any novel technological approaches such as phenotyping to rapidly select or find traits that are vital for the improvement of current germplasm to make them resilient to an ever-changing environment. Crop yield, especially grain yield, is a very complex trait to deconvolute and understand as it is influenced by so many factors. With the recent unprecedented weather events where plants are subjected to extreme temperatures (low and high), it is imperative to find ways quickly to screen for varieties that can withstand these changes. Novel ways or methods in the various disciplines (physiology, molecular, phenotyping, biochemical) that can help to identify rapidly the traits related to yield in crops that can lead to an increase in productivity will be informative and help the scientific community to be up to date with recent progress.