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| Author | : Richard G. Cutler |
| Publisher | : World Scientific |
| Total Pages | : 872 |
| Release | : 2003 |
| Genre | : Family & Relationships |
| ISBN | : 9812775730 |
This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.
| Author | : David R. Riddle |
| Publisher | : CRC Press |
| Total Pages | : 413 |
| Release | : 2007-04-19 |
| Genre | : Medical |
| ISBN | : 1420005529 |
Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur
| Author | : R.C. Cutler |
| Publisher | : Birkhäuser |
| Total Pages | : 393 |
| Release | : 2012-12-06 |
| Genre | : Science |
| ISBN | : 3034873379 |
Oxidative stress and aging Over the past several years there has been an extraordinarily rapid growth in our knowledge of free radical chemistry and its possible involvement in both normal essential biology and age related disease and dysfunction. Much of this growth in the traditionally separate sciences of chemistry and molecular gerontology occurred independently, with little interaction or communi cation between the scientists working in these two fields. In view of the growing maturity of the two fields and the potential importance of advancing our knowledge in the area of oxidative stress and aging, we perceived a critical need to organize an international conference the "First Inter national Conference on Oxidative Stress and Aging" in Hawaii in 1994 to bring together the world's leading scientists in the fields of reactive oxygen species and molecular gerontology. The objective of this conference was to provide a unique opportunity for scholars working in these two related and rapidly growing fields to participate in the exchange, integration, and synthesis of new concepts and ideas, to engage in constructive criticism and to initiate new collaborative research projects. The conference focused on the molecular and cellular aspects of aging as related to oxidative stress. It was one of the largest and most comprehensive international conferences held in molecular gerontology. At this conference a call was made for submission of papers to be used in the publication of a book covering the major contributions of the meeting.
| Author | : Lawrence J. Berliner |
| Publisher | : Springer Nature |
| Total Pages | : 237 |
| Release | : 2020-08-08 |
| Genre | : Science |
| ISBN | : 303047318X |
This book describes the methods of analysis and determination of oxidants and oxidative stress in biological systems. Reviews and protocols on select methods of analysis of ROS, RNS, oxygen, redox status, and oxidative stress in biological systems are described in detail. It is an essential resource for both novices and experts in the field of oxidant and oxidative stress biology.
| Author | : Richard G. Cutler |
| Publisher | : World Scientific |
| Total Pages | : 758 |
| Release | : 2003 |
| Genre | : Medical |
| ISBN | : 9789812389978 |
This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.
| Author | : Richard G Cutler |
| Publisher | : World Scientific |
| Total Pages | : 1621 |
| Release | : 2002-10-28 |
| Genre | : Medical |
| ISBN | : 9814490946 |
This innovative and comprehensive reference book provides the most up-to-date information pertaining to the translational research field of oxidative stress and aging. The book focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases with the goal being the development of new and novel methods in treating the human aging processes. The book charts the course of this new and rapidly emerging field of Oxidative Stress Diagnostics and Therapeutics that will have a significant impact on the future economics, science and practice of medicine. Over 100 of the leading experts in this field whose specialty includes biogerontology, geriatric medicine, free radical chemistry and biology, oncology, cardiology, neurobiology, dermatology, pharmacology, nutrition, and molecular medicine, have contributed information to this book. This reference book is an essential reading material to a broad range of individuals including researchers, physicians, corporate industry leaders, graduate and medical school students, as well as the many health conscious individuals who wish to know more about the emerging field of oxidative stress and aging with an emphasis on diagnostics and intervention.
| Author | : Zsolt Radák |
| Publisher | : Human Kinetics |
| Total Pages | : 286 |
| Release | : 2000 |
| Genre | : Health & Fitness |
| ISBN | : 9780880118811 |
Explore the emerging field of free radical biology, exercise, and aging with this definitive reference. Free Radicals in Exercise and Agingaddresses the current debate regarding whether free radicals released during exercise accelerate the aging process. It explains how free radicals can serve as important regulators of aerobic processes, and it clarifies the importance of exercise in increasing the efficiency of the antioxidant and oxidative repair systems. Mounting research data indicate that free radicals are involved in a variety of physiological and pathophysiological processes. This book focuses on exercise-induced adaptation. In general, a person's ability to adapt to internal and external changes decreases during the aging process. However, by continually exposing the body to different challenges, regular exercise triggers an adaptation process that keeps the body and mind fit. Free Radicals in Exercise and Agingelucidates the role of free radical species in regulating this process. This text is also one of the first to provide an in-depth review of skeletal muscle oxidative stress and aging. This issue is pivotal because muscle serves such a critical role in mobility and normal life. Free Radicals in Exercise and Aging shares the most current understanding of how reactive oxygen species influence the biology of skeletal muscles. It explores some of the unique characteristics that skeletal muscle displays during aging, both in terms of free radical production and with regard to antioxidant systems. The implications of this research are far-reaching. Mutation of DNA is linked very closely to cancer, and if regular exercise improves the regulation of the antioxidant systems and the oxidative damage repair system, these mechanisms may be a very important tool against this deadly disease. This research-oriented text presents the latest information on the subject. It reviews and critiques current literature and provides critical information for exercise physiologists, sports medicine specialists, sport nutritionists, and gerontologists.
| Author | : Donald Armstrong |
| Publisher | : John Wiley & Sons |
| Total Pages | : 610 |
| Release | : 2016-04-11 |
| Genre | : Science |
| ISBN | : 1118832485 |
Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.
| Author | : Helmut Sies |
| Publisher | : Academic Press |
| Total Pages | : 878 |
| Release | : 2019-11-07 |
| Genre | : Science |
| ISBN | : 0128196963 |
Oxidative Stress: Eustress and Distress presents current knowledge on oxidative stress within the framework of redox biology and translational medicine. It describes eustress and distress in molecular terms and with novel imaging and chemogenetic approaches in four sections: - A conceptual framework for studying oxidative stress. - Processes and oxidative stress responses. Signaling in major enzyme systems (oxidative eustress), and damaging modification of biomolecules (oxidative distress). - The exposome addresses lifelong exposure and impact on health, nutrient sensing, exercise and environmental pollution. - Health and disease processes, including ischemia-reperfusion injury, developmental and psychological disorders, hepatic encephalopathy, skeletal muscle disorders, pulmonary disease, gut disease, organ fibrosis, and cancer. Oxidative Stress: Eustress and Distress is an informative resource useful for active researchers and students in biochemistry, molecular biology, medicinal chemistry, pharmaceutical science, nutrition, exercise physiology, analytical chemistry, cell biology, pharmacology, clinical medicine, and environmental science. - Characterizes oxidative stress within the framework of redox biology, redox signaling, and medicine - Empowers researchers and students to quantify specific reactants noninvasively, identify redox biomarkers, and advance translational studies - Features contributions from international leaders in oxidative stress and redox biology research
| Author | : Robin Holliday |
| Publisher | : Cambridge University Press |
| Total Pages | : 228 |
| Release | : 1995-01-27 |
| Genre | : Medical |
| ISBN | : 9780521478021 |
This book presents a completely novel approach to the understanding of ageing, which many believe is an unsolved problem in biology. It explains why ageing exists in animals, and reviews our understanding of it at the biological level. This includes a discussion of the origins and evolution of ageing. The book is not a review of research on ageing, but instead draws on material from a wide range of disciplines, including the very extensive biomedical information about age-related diseases in humans. Understanding Ageing argues that much research needs to be done on the cellular and molecular aspects of ageing, if the origins of these diseases are to be understood, and their prevention made possible. This thought-provoking book will appeal to all students and researchers who are interested in ageing, whether they are working in the clinical or basic research sphere.
