Coxiella Burnetii Recent Advances And New Perspectives In Research Of The Q Fever Bacterium
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| Author | : Rudolf Toman |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 413 |
| Release | : 2012-06-19 |
| Genre | : Medical |
| ISBN | : 9400743157 |
Coxiella burnetii is the etiological agent of Q fever, a zoonotic disease found worldwide. The bacterium is a fascinating example of intracellular parasitism that has uniquely evolved to thrive in the most inhospitable of cellular compartments-the phagolysosome. Understanding how C. burnetii resists the degradative functions of this vacuole, and the host cell functions coopted for successful parasitism, are central to understanding Q fever pathogenesis. Recent achievements in glycomics and proteomics are guiding development of enhanced detection schemes for the bacterium in addition to shedding light on the host immune response to the pathogen. Several chapters survey immune functions that control or potentially exacerbate Coxiella infection and delve into correlates of protective immunity elicited by vaccination. Comparative genomics is also the foundation of chapters discussing diagnostic antigen discovery and molecular typing of the bacterium, with significance for development of new clinical, epidemiologic, and forensic tools.
| Author | : E. Mitscherlich |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 807 |
| Release | : 2012-12-06 |
| Genre | : Science |
| ISBN | : 364269974X |
This book is a collection of data on the tenacity in the environment of bacteria and some rickettsiae important in medicine and veterinary medicine. These data are of fundamental importance to physicians, veterinarians, epidemiologists and others when, in their practices, they are confronted with epidemics of contagious diseases or outbreaks of foodborne illnesses. At such times prompt answers are often needed to limit the problem, and thus to protect the public's health. Since data needed for such a purpose are widely distributed in the internatio nal scientific literature, the occasional desperate literature search is likely to miss some of the information that is available. This book seeks to fill that void. It lies in the nature of a compilation such as this is that it can never be totally complete. The compilation requires continual up-dating to include new information, and some currently acceptable information may have to be corrected as new data become available. However, most of the information in this compilation will never be out-of-date. The authors are always thankful for suggestions from others. Collection of the data in this book resulted from, first, several decades of studying the literature, and, second, literature searches made by the Institut fUr Dokumentationswesen in Frankfurt a. M. , the Biomedi zinische Datenbank of Hoechst A. G.
| Author | : Dongyou Liu |
| Publisher | : CRC Press |
| Total Pages | : 874 |
| Release | : 2014-04-08 |
| Genre | : Medical |
| ISBN | : 1466553987 |
Security sensitive microbes (viruses, bacteria, fungi, and parasites) and toxins, which are often referred to as the select agents and toxins, have the capacity to cause serious illness and death in humans, animals, and plants.This book is an authoritative and comprehensive review of security sensitive microbes (viruses, bacteria, fungi, and parasites) and toxins, with an emphasis on the state of the art in the field. Written by experts in the field, the chapters present authoritative reviews, each one covering a single microbe or toxin with respect to its classification, biology, epidemiology, pathogenesis, identification, diagnosis, treatment, and prevention. The chapters also discuss the limitations of our current knowledge and challenges relating to improved detection and control of the microbe or toxin.
| Author | : Joann Colville |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 264 |
| Release | : 2007-05-23 |
| Genre | : Medical |
| ISBN | : 0323070922 |
This essential, authoritative handbook provides clear, accurate coverage of zoonoses — diseases that can spread from animals to humans. The consistent format helps you quickly locate key information, such as how each disease affects the host, how it is spread, how it is treated, and necessary safety precautions. It also discusses the importance of educating animal owners about the public health implications of zoonoses and how to prevent them from spreading. - Clear, concise coverage helps you respond quickly when presented with diseases that could potentially spread between patients, clients, and staff in the veterinary clinic. - Each disease entry begins with a chart of its potential morbidity (the rate of incidence of a disease) and mortality (death rate), giving you at-a-glance access to the chance of contracting the disease and the severity of the disease if contracted. - Clinically relevant coverage includes information on the etiology (bacterial, viral, parasitic, etc.), most common nonhuman hosts, transmission modes, course of the disease, clinical signs in animals and humans, diagnostic tests, prevention, and general advice. - Essential information on preventing the spread of disease helps you educate clients about how to protect themselves and their animals from zoonoses. - Coverage of diseases such as mad cow disease, West Nile virus, rabies, and anthrax, prepares you to answer client questions about diseases that are in the public eye.
| Author | : Jasbir Singh Bedi |
| Publisher | : John Wiley & Sons |
| Total Pages | : 524 |
| Release | : 2022-06-28 |
| Genre | : Medical |
| ISBN | : 1119809533 |
Textbook of Zoonoses Comprehensive resource covering the aetiology, epidemiology and transmission cycle, clinical symptoms, diagnosis, and prevention and control strategies of the important zoonoses. Zoonoses are the diseases which can spread from animals to humans. This book covers all important zoonoses that are prevalent in today’s world. As a modern learning resource, it incorporates recent scientific developments and concepts to give readers a complete overview of each zoonoses. Written by three well-qualified authors in academia, sample topics covered within the book include: Bacterial, viral, parasitic, rickettsial, fungal, prion, and foodborne zoonoses Aetiology and epidemiology of each zoonotic disease Clinical symptoms and diagnosis in animals and humans Treatment options, plus prevention and control strategies CDC classification of zoonotic agents and the WHO’s list of ‘neglected zoonoses’ Written for undergraduate and postgraduate students studying veterinary public health and epidemiology, Textbook of Zoonoses is also a helpful resource for other veterinary and medical professionals interested in public health and epidemiology.
| Author | : Yasobant, Sandul |
| Publisher | : IGI Global |
| Total Pages | : 306 |
| Release | : 2019-03-01 |
| Genre | : Medical |
| ISBN | : 1522563059 |
Many factors have changed interactions between people, animals, and our environment including the emergence and reemergence of diseases such as swine flu, rabies, and diphtheria. By practicing the concept of one health, which relates the close interactions between people, animals, and our environment to overall health, a solution for global wellbeing can be found. Global Applications of One Health Practice and Care provides in-depth research on the concept of one health and the ability to achieve universal health by connecting human health with animal health and a safe environment. Featuring coverage on a broad range of topics such as holism health, drug resistance, and parasitic zoonoses, this book is ideally designed for policy planners, program managers, public health practitioners, animal health specialists, environmentalists, researchers, and academicians seeking current research on achieving better public health outcomes.
| Author | : Jeffrey Ryan |
| Publisher | : Butterworth-Heinemann |
| Total Pages | : 394 |
| Release | : 2016-02-18 |
| Genre | : Political Science |
| ISBN | : 0128020571 |
Biosecurity and Bioterrorism, Second Edition, takes a holistic approach to biosecurity, with coverage of pathogens, prevention, and response methodology. It addresses these hazards in the context of vulnerability assessments and the planning strategies government and industry can use to prepare for and respond to such events. The book is organized into four thematic sections: Part I provides a conceptual understanding of biowarfare, bioterrorism and the laws we have to counteract this; Part II investigates known bioagents and the threat from emerging diseases; Part III focuses on agricultural terrorism and food security; and Part IV outlines international, US, and local initiatives for biodefense and biosecurity. Case studies illustrate biodefense against both intentional terrorism and natural outbreaks. - Covers emerging threats of pandemic influenza, antibiotic resistant strains of bacterial pathogens, and severe respiratory diseases caused by novel viruses - Offers increased international coverage, including initiatives to counter biological weapons and threats, and food security - Updated throughout with latest protocols for dealing with biological threats and new case studies - Includes online instructor ancillaries - PowerPoint lecture slides, test questions, and an instructor manual, for increased classroom functionality
| Author | : Rey Carabeo |
| Publisher | : Frontiers Media SA |
| Total Pages | : 223 |
| Release | : 2024-07-08 |
| Genre | : Science |
| ISBN | : 2832551394 |
Obligate intracellular parasitism is the associated with genome reduction, which is the process of reconfiguring the genome through systematic elimination of genetic loci deemed unnecessary. The end-result is an increasing dependence on the host for various factors essential for growth, such as nutrients and a protective intracellular replicative niche. The extreme genome reduction that some of the obligate intracellular bacteria have undergone, while maintaining viability and virulence has revealed the level of adaptability, including a plethora of survival strategies that more often than not functionally converge to modulate similar host cell processes, such as cytoskeletal dynamics, vesicular transport, and pathogen recognition, among others. With the advent of molecular genetic approaches, and in the case of Coxiella, growth in axenic media, the field of obligate intracellular pathogen research has progressed rapidly in the past five years, redefining obligate intracellular parasitism as the field transitions from descriptive to mechanism-based research. An emerging theme is the adaptability and ingenuity of this class of pathogens. Genome reduction prioritizes survival, but because this occurs within a host, there is also the need to maintain virulence. As such, survival strategies become intertwined, and likely inseparable from virulence strategies. The purpose of this Special Topics Issue is to bring together in one volume review articles from experts in the field. This issue will have a broad scope. Articles will describe the current state of knowledge in genetics and genomics, metabolism, cell biology of infection, immune evasion, and vaccine design. Importantly, cutting-edge information will also be discussed in the context of past seminal findings, and future directions of research. Overall, this Special Topics Issue should serve as a valuable reference to colleagues and those new to the field of obligate intracellular pathogens research. We welcome submission of review and mini-review articles on the following topics: • Genome structure • Development of genetic tools • Molecular mechanisms of adhesion, invasion, and other early events in infection • Establishment of the intracellular niche • Niche interactions with organelles • Translocation of effectors • Metabolism and metabolic adaptations • Gene regulation during stress response • Pathogen recognition and immune evasion strategies • Innate and adaptive immunity during infection • Experimental models
| Author | : Didier Raoult |
| Publisher | : CRC Press |
| Total Pages | : 400 |
| Release | : 2007-04-26 |
| Genre | : Medical |
| ISBN | : 142001997X |
The only available reference to comprehensively discuss the common and unusual types of rickettsiosis in over twenty years, this book will offer the reader a full review on the bacteriology, transmission, and pathophysiology of these conditions. Written from experts in the field from Europe, USA, Africa, and Asia, specialists analyze specific patho
| Author | : Muhammad Abubakar |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 184 |
| Release | : 2019-03-13 |
| Genre | : Medical |
| ISBN | : 1789857651 |
It is vital to understand ticks and tick-borne pathogens as well as their impact on humans. This book is intended for students in parasitology, biologists, parasitologists involved in molecular diagnostics of tick-borne diseases, practicing veterinarians, and for others who may require information on ticks and tick-borne diseases. Here we have put together a collection of chapters focused on different aspects of ticks and tick-borne diseases mainly to provide the reader with novel information in the field, but not the basic generalised information provided by many textbooks. This book includes topics such as high-throughput technologies in diagnosis, discovery of novel tick vaccines, identification of new pathogens transmitted by ticks, and new epidemiological information of certain well-known ticks and tick-borne diseases. These chapters were authored by parasitologists from all over the world, giving an insight to the reader about significant ticks and tick-borne diseases prevalent in those particular geographical regions with the local expert's point of view. Each of the chapters has separate reference lists, making it easier for the reader to find additional reading material related to their topic of interest.
