Cord Blood

Cord Blood
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 334
Release: 2005-10-26
Genre: Medical
ISBN: 0309165172

With the potential for self-renewal and differentiation, the possibilities for stem cells are enormous. One specific type of stem cell, the hematopoietic progenitor cell (HPC), which is derived from umbilical cord blood (as well as adult bone marrow and mobilized peripheral blood), holds particular promise. To make the most of these HPCs, the Institute of Medicine was asked to consider the optimal structure for a national cord blood program and to address pertinent issues related to maximizing the potential of stem cell technology. Cord Blood: Establishing a National Hematopoietic Stem Cell Bank Program examines: The role of cord blood in stem cell transplantation The current status of blood banks already in existence The optimal structure for the cord blood program The current use and utility of cord blood for stem cell transplants The best way to advance the use of cord blood units and make them available for research Expert advice from leaders in the fields of economics, public health, medicine, and biostatistics combine to make this very timely and topical book useful to a number of stakeholders.

Vascular Biology of the Placenta

Vascular Biology of the Placenta
Author: Yuping Wang
Publisher: Biota Publishing
Total Pages: 126
Release: 2017-06-23
Genre: Medical
ISBN: 1615047514

The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.

Frontiers of Cord Blood Science

Frontiers of Cord Blood Science
Author: Niranjan Bhattacharya
Publisher: Springer
Total Pages: 0
Release: 2010-10-13
Genre: Medical
ISBN: 9781849967426

Cord blood is a significant source of hematopoietic stem and progenitor cells for the treatment of blood and genetic disorders. Cord blood is also an alternative to embryos as a source of tissue for regenerative medicine. Cells from cord blood have been shown to transdifferentiate into nonhematopoietic cells, including those of the brain, heart, liver, pancreas, bone, and cartilage, in tissue culture and in animal systems. Recently it has been demonstrated that both cardiac and glial cell differentiation of cord blood donor cells occurred in recipients of unrelated donor cord blood transplantation as part of a treatment regime for Krabbe disease and Sanfilippo syndrome. These observations raise the possibility that cord blood may serve as a source of cells to facilitate tissue repair and regeneration in the future. CD34 stem cell-rich umbilical cord whole blood transfusion has the potential to have an immediate benefit of better tissue oxygenation with an additional delayed benefit of possible engraftment of umbilical cord stem cells.

Umbilical Cord Blood: A Future For Regenerative Medicine?

Umbilical Cord Blood: A Future For Regenerative Medicine?
Author: Suzanne Kadereit
Publisher: World Scientific Publishing Company
Total Pages: 372
Release: 2010-12-23
Genre: Science
ISBN: 9813107316

Umbilical cord blood, previously discarded, has emerged as a new source of stem cells for hematologic reconstitution, bone marrow failures and other hematologic deficiencies. It has become increasingly clear that umbilical cord tissue contains unique stem cells of great potential for regenerative medicine. Importantly, umbilical cord blood is abundant, can be banked and transported with ease, and thus has an indisputable potential for future regenerative therapies. Driven by a massive interest for regenerative medicine and ethically acceptable stem cell sources, the scientific literature on umbilical cord stem cells has exploded.This book provides a consolidated overview of basic, translational as well as clinical research in academic institutions and industry, on hematopoietic and mesenchymal stem cells contained within umbilical cord tissue, as well as other more recently discovered stem and precursor cells of not yet fully elucidated potential. Although not discussed here, umbilical cord cells have been successfully reprogrammed into pluripotent stem cells (iPS), opening the door for a vast array of applications with this abundant human material likely catapulting cord-derived stem cells to the forefront of cell-based regenerative medicine.Suitable as a primer and reference book for medical fellows and researchers, this book can also be used by students (undergraduate and graduate) as a starting point into the vast literature on stem cells and their potential.

The European Blood and Marrow Transplantation Textbook for Nurses

The European Blood and Marrow Transplantation Textbook for Nurses
Author: Michelle Kenyon
Publisher: Springer
Total Pages: 318
Release: 2018-03-14
Genre: Medical
ISBN: 3319500260

This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Gene Technology

Gene Technology
Author: Axel R. Zander
Publisher: Springer Science & Business Media
Total Pages: 534
Release: 2013-06-29
Genre: Science
ISBN: 3642611222

The 11 th meeting in "Modern Trends in Human Leukemia" took place from June 19 to 21, 1994 in Wilsede in the middle of the Liineburger Heide, South of Hamburg. Interwoven with the Leukemia program was the Nato-sponsored Symposium of the ASI-Series "Gene Technology in Analysis of Malignant and Inherited Human Diseases Related to Development" . The Wilsede meeting was continued on a ship of the Neva leading through lake Ladoga and lake Onega. The topics of both meetings included discussion on recent progress isolation and development of hematopoietic stem cells, genes crucial for development and diseases, methods of gene transfer, application of gene transfer; oncogenes and anti-oncogenes as targets for gene therapy; receptors and their ligands in normal development and diseases, immunology and immunotherapy, radiation biology, clinical leukemias and bone marrow transplantation. The Nato workshop concentrated not only on analysis of cell systems useful for somatic gene therapy, but also on actual themes directly related to correction of human diseases. The latter aspects emphasized themes related to biotechnology, the first part was by nature more general. We also included a few contributions that discussed perspectives for the future of gene therapy and possible relationships to evolution.

Neonatal Encephalopathy and Neurologic Outcome

Neonatal Encephalopathy and Neurologic Outcome
Author: American College of Obstetricians and Gy
Publisher: American College of Obstetricians and Gynecologists Women's Health Care Physicians
Total Pages: 0
Release: 2014
Genre: Medical
ISBN: 9781934984307

Significantly revised and updated, the new second edition updates the science on neonatal encephalopathy presented in the 1st edition. The new 2nd edition recommends a broad evaluation of all potential contributing factors in every case of neonatal encephalopathy, including maternal medical history, obstetric and intrapartum factors, and placental pathology. This recommendation is a shift from the 2003 report, which focused on determining whether or not a hypoxic-ischemic event was the cause of neonatal encephalopathy. Includes new sections on - Placental pathology - Focal ischemic stroke - Neonatal interventions - Patient safety - Significant advances in neuroimaging This report will assist the clinician in evaluating a newborn with encephalopathy to assist in defining both the cause and timing.

Umbilical Cord Stem Cell Therapy

Umbilical Cord Stem Cell Therapy
Author: David A. Steenblock
Publisher: Basic Health Publications, Inc.
Total Pages: 202
Release: 2006
Genre: Health & Fitness
ISBN: 9781591201250

Examines the potential for stem cells gleaned from umbilical cords to generate a wealth of new therapy and healing medicines for neurological conditions and blood problems.

Cord Blood

Cord Blood
Author: Lisandra Vanostrand
Publisher: Nova Science Publishers
Total Pages: 0
Release: 2013
Genre: Medical
ISBN: 9781626180727

In this book, the authors discuss cord blood banks and banking, the ethical issues involved and the risks and benefits. Topics include the virological risks and benefits of cord blood banking; mesenchymal stem cells and their role in regenerative medicine applications; osteogenic potential of human umbilical cord-derived mesenchymal stromal cells; public versus private cord blood banking; CCR5 deficient cord blood as a means of treatment for HIV-1 infection; and the therapeutic use of umbilical cord blood.