Persistent Viral Infections

Persistent Viral Infections
Author: R. Ahmed
Publisher: Wiley-Blackwell
Total Pages: 754
Release: 1999
Genre: Medical
ISBN:

Persistent Viral Infections Edited by Rafi Ahmed Emory Vaccine Center, Atlanta, USA and Irvin S. Y. Chen UCLA School of Medicine, Los Angeles, USA During the past decade much of our attention has focused on diseases associated with viral persistence. Major breakthroughs in immunology, and the advent of molecular approaches to study pathogenesis have increased our understanding of the complex virus-host interactions that occur during viral persistence. Persistent Viral Infections focuses on: * The pathogenesis and immunology of chronic infections * Animal models that provide, or have the potential to provide, major insights This volume will be essential reading for virologists, immunologists, oncologists and neurologists.

Antiviral Chemotherapy

Antiviral Chemotherapy
Author: D. J. Jeffries
Publisher:
Total Pages: 614
Release: 1995-07-11
Genre: Medical
ISBN:

Considerable advances have been made in the treatment of antiviral diseases over the last decade. Several new drugs have been introduced while new clinical information has been gathered on the efficacy of existing drugs. This study aims to provide an examination of the basic science (drug formulae, structure and biochemical activity) and clinical information (usage and efficacy) on chemotherapy, as well as describing future potentials.

Viral Infections of Humans

Viral Infections of Humans
Author: Alfred S. Evans
Publisher: Springer Science & Business Media
Total Pages: 744
Release: 2013-11-11
Genre: Medical
ISBN: 1468447270

also occurs. New outbreaks of yellow fever have occurred in Colombia and Trinidad and new outbreaks of rift valley fever have occurred in Egypt. Chapter 6, Arenaviruses: The biochemical and physical properties have now been clar ified, and they show a remarkable uniformity in the various viruses constituting the group. The possibility that prenatal infection with LCM may result in hydrocephalus and chorioretinitis has been raised. Serologic surveys have suggested the existence of Lassa virus infection in Guinea, Central African Empire, Mali, Senegal, Cameroon, and Benin, in addition to earlier identification in Nigeria, Liberia, and Sierra Leone. Chapter 7, Coronaviruses: New studies have confirmed the important role of these viruses in common respiratory illnesses of children and adults. The viruses are now known to contain a single positive strand of RNA. About 50% of corona virus infections result in clinical illness. About 5% of common colds are caused by strain DC 43 in winter. Chapter 8, Cytomegalovirus: Sections on pathogenesis of CMV in relation to organ transplantation and mononucleosis, as well as sections on the risk and features of con genital infection and disease, have been expanded. There are encouraging preliminary results with a live CMV vaccine, but the questions of viral persistence and oncogenicity require further evaluation.

Emerging Viral Diseases

Emerging Viral Diseases
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 310
Release: 2015-03-19
Genre: Medical
ISBN: 0309314003

In the past half century, deadly disease outbreaks caused by novel viruses of animal origin - Nipah virus in Malaysia, Hendra virus in Australia, Hantavirus in the United States, Ebola virus in Africa, along with HIV (human immunodeficiency virus), several influenza subtypes, and the SARS (sudden acute respiratory syndrome) and MERS (Middle East respiratory syndrome) coronaviruses - have underscored the urgency of understanding factors influencing viral disease emergence and spread. Emerging Viral Diseases is the summary of a public workshop hosted in March 2014 to examine factors driving the appearance, establishment, and spread of emerging, re-emerging and novel viral diseases; the global health and economic impacts of recently emerging and novel viral diseases in humans; and the scientific and policy approaches to improving domestic and international capacity to detect and respond to global outbreaks of infectious disease. This report is a record of the presentations and discussion of the event.

Plant Virus and Viroid Diseases in the Tropics

Plant Virus and Viroid Diseases in the Tropics
Author: K. Subramanya Sastry
Publisher: Springer Science & Business Media
Total Pages: 511
Release: 2014-01-06
Genre: Science
ISBN: 9400778201

Around the globe, besides fungal and bacterial diseases, both virus and viroid diseases have acquired greater importance in the realm of plant pathology and call for effective management measures as they are responsible for heavy yield losses and are a matter of vital importance and concern to farmers, horticulturists, gardeners and foresters. Understanding disease epidemiology is of vital importance for formulating viable disease management practices in a given agro-ecosystem. The development and progress of plant disease epidemics are variable from region to region. Epidemiology is not a static process, but rather a dynamic course that varies with a change in the ecology, host, vector and virus systems.

Handbook of Plant Virus Diseases

Handbook of Plant Virus Diseases
Author: Dragoljub D. Sutic
Publisher: CRC Press
Total Pages: 582
Release: 1999-06-15
Genre: Science
ISBN: 9780849323027

Handbook of Plant Virus Diseases presents basic information about viral-caused and viral-like diseases in many cultivated crops. The editors, internationally known plant pathologists, provide authoritative descriptive symptomatic signatures of virus diseases, to aid in the diagnosis and possible control of viruses. This handbook organizes cultivated plants into groups according to their final destinations and uses after harvest-a useful grouping system that indicates that some diseases, their resultant epidemiology, and control measures are characteristic within different groups.

Gene Therapy for Viral Infections

Gene Therapy for Viral Infections
Author: Patrick Arbuthnot
Publisher: Academic Press
Total Pages: 391
Release: 2015-06-01
Genre: Science
ISBN: 0124114520

Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors. Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology. - Provides coverage of gene therapy for a variety of infections, including HBV, HCV, HIV, hemorrhagic fever viruses, and respiratory and other viral infections - Bridges the gap between the basic science and the important medical applications of this technology - Features a broad approach to the topic, including an essential overview and the applications of gene therapy, synthetic RNA, and other antiviral strategies that involve nucleic acid engineering - Presents perspectives on the future use of nucleic acids as a novel class of antiviral drugs - Arms the reader with the cutting-edge information needed to stay abreast of this developing field