Contrast Agents For Body Mr Imaging
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Author | : Marco Essig |
Publisher | : Elsevier Health Sciences |
Total Pages | : 223 |
Release | : 2012-11-28 |
Genre | : Medical |
ISBN | : 1455749788 |
MRI contrast agents improve visibility of internal body structures. This issue offers a complete, practically focused review of the use of a variety of contrast agents for MR Imaging. A contrast agent not only must be safe, but also efficacious and cost-effective, and the articles in this issue address all three of these concerns and the uses of contrast agents for a variety of applications.
Author | : |
Publisher | : |
Total Pages | : 189 |
Release | : 1996 |
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Author | : Henrik S. Thomsen |
Publisher | : Springer Science & Business Media |
Total Pages | : 240 |
Release | : 2009-03-23 |
Genre | : Medical |
ISBN | : 3540727833 |
This revised edition of Contrast Media: Safety Issues and Guidelines, updates the successful first edition and contains new chapters. It provides an invaluable, unique and unparalleled source of information on the safety issues relating to contrast media.
Author | : Vincent Hok Liu |
Publisher | : |
Total Pages | : 141 |
Release | : 2014 |
Genre | : |
ISBN | : |
Magnetic resonance imaging (MRI) is frequently used for examining the human body. MRI contrast agents currently used in the clinic assist physicians in locating problematic areas, but other tools are needed to interrogate the chemical environment of these areas once found. The fast clearance rate of contrast agents, in particular, makes quantitative assessment of local tissue with MR difficult. This thesis focuses on the development of solid MRI contrast agents designed for longterm, quantitative monitoring of local metabolites. Two types of contrast agents are described in this thesis. Contrast agents sensitive to oxygen were made by encapsulating low molecular weight siloxanes in a polydimethylsiloxane (PDMS) matrix. The PDMS matrix is biocompatible and prevents clearance of the contrast material. The longitudinal relaxation time, T1, of these agents is proportional to the amount of dissolved oxygen in the material and is indicative of local oxygen tension. A microparticulate formulation of these agents was tested in a rat model and was shown to be stable for up to one month in vivo. These results suggested that the encapsulated agents enjoyed an order of magnitude improvement in stability over a simple liquid contrast agent injection. Contrast agents sensitive to changes in pH were made of a polymerized hydroxlethylmethacrylate (HEMA) hydrogel and used with the microresonator sensor previously developed in the Cima Lab. These sensors reversibly detected changes in pH in flowing liquid for up to three weeks, and detected the different pH of a tumor compared to control locations.
Author | : Werner Krause |
Publisher | : Springer |
Total Pages | : 251 |
Release | : 2003-07-01 |
Genre | : Science |
ISBN | : 354045733X |
Extracellular MRI and X-ray contrast agents are characterized by their phar- cokinetic behaviour.After intravascular injection their plasma-level time curve is characeterized by two phases. The agents are rapidly distributed between plasma and interstitial spaces followed by renal elimination with a terminal half-live of approximatly 1–2 hours. They are excreted via the kidneys in unchanged form by glomerular filtration. Extracellular water-soluble contrast agents to be applied for X-ray imaging were introduced into clinical practice in 1923. Since that time they have proved to be most valuable tools in diagnostics.They contain iodine as the element of choice with a sufficiently high atomic weight difference to organic tissue. As positive contrast agents their attenuation of radiation is higher compared with the attenuation of the surrounding tissue. By this contrast enhancement X-ray diagnostics could be improved dramatically. In 2,4,6-triiodobenzoic acid derivatives iodine is firmly bound. Nowadays diamides of the 2,4,6-triiodo-5-acylamino-isophthalic acid like iopromide (Ultravist, Fig. 1) are used as non-ionic (neutral) X-ray contrast agents in most cases [1].
Author | : Ernst Rummeny |
Publisher | : Thieme |
Total Pages | : 704 |
Release | : 2011-01-01 |
Genre | : Medical |
ISBN | : 3131496010 |
This lavishly illustrated book is a comprehensive guide to the basic principles and clinical applications of MR imaging for all regions of the body. The opening chapter provides a thorough overview of the basic principles for MR imaging, contrast agents, risks and side effects associated with MR imaging, and common imaging artifacts. The remaining chapters address common pathological findings in the head and neck, thorax, female breast, abdomen, pelvis, lymph nodes, musculoskeletal system, and vessels. A final chapter discusses the applications of whole-body MRI, whole-body MR angiography, and high-field MRI at 3 T. Features: Clear guidelines on how to perform techniques, select the appropriate contrast media, attain the best images, and analyze the findings More than 100 differential diagnosis tables that are ideal for at-a-glance review Detailed comparisons of MR findings and findings using other modalities 1,350 high-quality images and illustrations demonstrating important concepts Bulleted lists of MRI Specifics highlighting key points This practical, user-friendly text is a valuable resource for residents and fellows in radiology. It is also an ideal reference for seasoned radiologists seeking to sharpen their MR diagnostic imaging skills.
Author | : Val M. Runge |
Publisher | : University Press of Kentucky |
Total Pages | : 192 |
Release | : 2014-10-17 |
Genre | : Medical |
ISBN | : 0813159067 |
In Contrast-Enhanced Clinical Magnetic Resonance Imaging, Val M. Runge and other leading experts present an overview of the basic principles regarding MR contrast media, a review of clinical applications in the head, spine, and body, and a look at future developments. Their focus is on clinical applications, with extensive illustrations to demonstrate the use of MR in each anatomic area and to aid in film interpretation.
Author | : Raymond Y. Kwong |
Publisher | : Springer |
Total Pages | : 473 |
Release | : 2019-01-31 |
Genre | : Medical |
ISBN | : 1493988417 |
The significantly updated second edition of this important work provides an up-to-date and comprehensive overview of cardiovascular magnetic resonance imaging (CMR), a rapidly evolving tool for diagnosis and intervention of cardiovascular disease. New and updated chapters focus on recent applications of CMR such as electrophysiological ablative treatment of arrhythmias, targeted molecular MRI, and T1 mapping methods. The book presents a state-of-the-art compilation of expert contributions to the field, each examining normal and pathologic anatomy of the cardiovascular system as assessed by magnetic resonance imaging. Functional techniques such as myocardial perfusion imaging and assessment of flow velocity are emphasized, along with the exciting areas of artherosclerosis plaque imaging and targeted MRI. This cutting-edge volume represents a multi-disciplinary approach to the field, with contributions from experts in cardiology, radiology, physics, engineering, physiology and biochemistry, and offers new directions in noninvasive imaging. The Second Edition of Cardiovascular Magnetic Resonance Imaging is an essential resource for cardiologists and radiologists striving to lead the way into the future of this important field.
Author | : Donald W. McRobbie |
Publisher | : Cambridge University Press |
Total Pages | : 405 |
Release | : 2017-04-13 |
Genre | : Medical |
ISBN | : 1316688259 |
MR is a powerful modality. At its most advanced, it can be used not just to image anatomy and pathology, but to investigate organ function, to probe in vivo chemistry, and even to visualise the brain thinking. However, clinicians, technologists and scientists struggle with the study of the subject. The result is sometimes an obscurity of understanding, or a dilution of scientific truth, resulting in misconceptions. This is why MRI from Picture to Proton has achieved its reputation for practical clarity. MR is introduced as a tool, with coverage starting from the images, equipment and scanning protocols and traced back towards the underlying physics theory. With new content on quantitative MRI, MR safety, multi-band excitation, Dixon imaging, MR elastography and advanced pulse sequences, and with additional supportive materials available on the book's website, this new edition is completely revised and updated to reflect the best use of modern MR technology.
Author | : P. Reimer |
Publisher | : Springer Science & Business Media |
Total Pages | : 604 |
Release | : 2006-05-11 |
Genre | : Medical |
ISBN | : 3540315551 |
This book offers practical guidelines for performing efficient and cost-effective MRI examinations. By adopting a practical protocol-based approach the work-flow in a MRI unit can be streamlined and optimized. All chapters have been thoroughly reviewed, and new techniques and figures are included. There is a new chapter on MRI of the chest. This book will help beginners to implement the protocols and will update the knowledge of more experienced users.