Connectomic Deep Brain Stimulation

Connectomic Deep Brain Stimulation
Author: Andreas Horn
Publisher: Academic Press
Total Pages: 602
Release: 2021-09-10
Genre: Medical
ISBN: 0128218622

Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson’s Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more. This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery. Written to provide a "hands-on" approach for neuroscience graduate students, as well as medical personnel from the fields of neurology and neurosurgery Includes preprocessing strategies (such as co-registration, normalization, lead localization, VTA estimation and fiber-tracking approaches) Presents references (key articles, books and protocols) for additional detailed study Provides data analysis boxes in each chapter to help with data interpretation

Connectomic Deep Brain Stimulation

Connectomic Deep Brain Stimulation
Author: Andreas Horn
Publisher: Elsevier
Total Pages: 600
Release: 2021-09-13
Genre: Medical
ISBN: 0128218614

Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson's Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more. This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery. Written to provide a "hands-on" approach for neuroscience graduate students, as well as medical personnel from the fields of neurology and neurosurgery Includes preprocessing strategies (such as co-registration, normalization, lead localization, VTA estimation and fiber-tracking approaches) Presents references (key articles, books and protocols) for additional detailed study Provides data analysis boxes in each chapter to help with data interpretation

Stereotactic and Functional Neurosurgery

Stereotactic and Functional Neurosurgery
Author: Nader Pouratian
Publisher: Springer Nature
Total Pages: 563
Release: 2020-02-28
Genre: Medical
ISBN: 3030349063

This text presents a comprehensive and state-of the-art approach to stereotactic and functional neurosurgery. Overarching sections include achieving stereotactic precision, defining trajectories and targets, the biophysics of stereotactic therapies, diseases and targets, and the future of functional neurosurgery. Each section is designed to be inclusive of all relevant topics, serving as an unbiased resource to new clinicians in this field or established clinicians that are aiming to better understand complementary methods. Importantly, each section and the associated chapters can be used by basic and translational scientists as well as engineers and industry to better understand and deliver innovation to the field. Chapters within each section methodically analyze traditional and recently emerging concepts and techniques; address underlying principles with examples drawn from specific diseases and applications; and cover patient selection, target selection, available stereotactic methods, nuanced surgical methods, and clinical evidence across treatment options. Written by experts in each area, Stereotactic and Functional Neurosurgery is a definitive guide to the latest developments in stereotactic targeting, electrode implantation, surgical treatment of neurological and psychiatric disorders, the renaissance of stereotactic lesions, and the frontier of restorative neurosurgery for a variety of disorders that have no other therapeutic options.

Neuromodulation in Psychiatry

Neuromodulation in Psychiatry
Author: Clement Hamani
Publisher: John Wiley & Sons
Total Pages: 518
Release: 2016-01-26
Genre: Medical
ISBN: 1118801040

Edited by an expert multidisciplinary team, Neuromodulation in Psychiatry is the first reference guide to address both invasive and non-invasive neuromodulation strategies used in psychiatry. Covers basic principles, technical aspects, clinical applications and ethical considerations Presents up-to-date evidence in comprehensive summaries suitable for all levels of experience Each technique is clearly explained along with its implications for real-world clinical practice Allows psychiatrists to make informed decisions regarding neuromodulation for their patients

The Hidden Life of the Basal Ganglia

The Hidden Life of the Basal Ganglia
Author: Hagai Bergman
Publisher: MIT Press
Total Pages: 333
Release: 2021-10-12
Genre: Science
ISBN: 0262367297

The anatomy and physiology of the basal ganglia and their relation to brain and behavior, disorders and therapies, and philosophy of mind and moral values. The main task of the basal ganglia—a group of subcortical nuclei, located at the base of the brain—is to optimize and execute our automatic behavior. In this book, Hagai Bergman analyzes the anatomy and physiology of the basal ganglia, discussing their relation to brain and behavior, to disorders and therapies, and even to moral values. Drawing on his forty years of studying the basal ganglia, Bergman presents new information on physiology and computational models, Parkinson’s disease and other ganglia-related disorders, and such therapies as deep brain stimulation. Focusing on studies of nonhuman primates and human basal ganglia and relying on system physiology and in vivo extra-cellular recording techniques, Bergman first describes the major brain structures that constitute the basal ganglia, the morphology of their cellular elements, their synaptic connectivity and their physiological function in health and disease. He discusses the computational physiology of the healthy basal ganglia, describing four generations of computational models, and then traces the computational physiology of basal ganglia–related disorders and their treatments, including Parkinson’s disease and its pharmacological and surgical therapies. Finally, Bergman considers the implications of these findings for such moral concerns as free will. Explaining this leap into domains rarely explored in neuroscientific accounts, Bergman writes that the longer he studies the basal ganglia, the more he is convinced that they are truly the base of both brain and mind.

PET and SPECT in Neurology

PET and SPECT in Neurology
Author: Rudi A.J.O. Dierckx
Publisher: Springer
Total Pages: 1103
Release: 2014-06-02
Genre: Medical
ISBN: 3642543073

PET and SPECT in Neurology highlight the combined expertise of renowned authors whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Classical neurodegenerative disorders are discussed as well as cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders and inflammatory and infectious diseases of the CNS. The latest results in nuclear brain imaging are detailed. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state-of-the-art compendium will be valuable not only to neurologists and radiologists/nuclear medicine specialists but also to interested general practitioners and geriatricians. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences, the other volumes covering PET and SPECT in psychiatry and in neurobiological systems.

Deep Brain Stimulation

Deep Brain Stimulation
Author: Shilpa Chitnis MD, PhD
Publisher: Oxford University Press
Total Pages: 256
Release: 2020-06-30
Genre: Medical
ISBN: 0190647213

Deep Brain Stimulation addresses the practical tips required to program and manage deep brain stimulation devices in the clinic. The number of deep brain stimulation devices worldwide will soon eclipse 200,000 and is an approved surgical treatment for medically refractory neurological movement disorders such as Parkinson disease, tremors, and dystonia. It is, therefore, inevitable that clinicians and nurses will require the necessary tools, and exemplary real-life cases, to manage these complex patients. This book offers a case-based approach to common and uncommon neurologic problems related to deep brain stimulator problems. Each case is a clinical pearl, accompanied by a discussion as well as practical tips to improve patient management.

The Student's Guide to Cognitive Neuroscience

The Student's Guide to Cognitive Neuroscience
Author: Jamie Ward
Publisher: Psychology Press
Total Pages: 549
Release: 2015-02-11
Genre: Psychology
ISBN: 1317586018

Reflecting recent changes in the way cognition and the brain are studied, this thoroughly updated third edition of the best-selling textbook provides a comprehensive and student-friendly guide to cognitive neuroscience. Jamie Ward provides an easy-to-follow introduction to neural structure and function, as well as all the key methods and procedures of cognitive neuroscience, with a view to helping students understand how they can be used to shed light on the neural basis of cognition. The book presents an up-to-date overview of the latest theories and findings in all the key topics in cognitive neuroscience, including vision, memory, speech and language, hearing, numeracy, executive function, social and emotional behaviour and developmental neuroscience, as well as a new chapter on attention. Throughout, case studies, newspaper reports and everyday examples are used to help students understand the more challenging ideas that underpin the subject. In addition each chapter includes: Summaries of key terms and points Example essay questions Recommended further reading Feature boxes exploring interesting and popular questions and their implications for the subject. Written in an engaging style by a leading researcher in the field, and presented in full-color including numerous illustrative materials, this book will be invaluable as a core text for undergraduate modules in cognitive neuroscience. It can also be used as a key text on courses in cognition, cognitive neuropsychology, biopsychology or brain and behavior. Those embarking on research will find it an invaluable starting point and reference. The Student’s Guide to Cognitive Neuroscience, 3rd Edition is supported by a companion website, featuring helpful resources for both students and instructors.

Cognition in Parkinson's Disease

Cognition in Parkinson's Disease
Author:
Publisher: Elsevier
Total Pages: 490
Release: 2022-03-02
Genre: Psychology
ISBN: 0323901654

Cognition in Parkinson's Disease, Volume 269 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Cognition in Prodromal Parkinson’s disease, The epidemiology of cognitive function in Parkinson's disease, Real-life consequences of cognitive dysfunction in Parkinson’s disease, Animal models of cognition in Parkinson’s disease, Functional neuroanatomy of cognition in Parkinson’s disease, Neuroimaging approaches to cognition in Parkinson’s disease, Cognitive dysfunction and neuropsychiatric aspects of Parkinson’s disease, Neuropsychology of Parkinson’s disease, Cholinergic Systems, Attentional-Motor Integration, and Cognitive Control in Parkinson Disease, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Progress in Brain Research series Updated release includes the latest information on Cognition in Parkinson's Disease