Concepts Of Alzheimer Disease
Download Concepts Of Alzheimer Disease full books in PDF, epub, and Kindle. Read online free Concepts Of Alzheimer Disease ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author | : Peter J. Whitehouse |
Publisher | : JHU Press |
Total Pages | : 343 |
Release | : 2003-05-27 |
Genre | : Health & Fitness |
ISBN | : 0801877156 |
As the essays in this volume show, conceptualizing dementia has always been a complex process. With contributions from noted professionals in psychiatry, neurology, molecular biology, sociology, history, ethics, and health policy, Concepts of Alzheimer Disease looks at the ways in which Alzheimer disease has been defined in various historical and cultural contexts. The book covers every major development in the field, from the first case described by Alois Alzheimer in 1907 through groundbreaking work on the genetics of the disease. Essays examine not only the prominent role that biomedical and clinical researchers have played in defining Alzheimer disease, but also the ways in which the perspectives of patients, their caregivers, and the broader public have shaped concepts.
Author | : Harald Hampel |
Publisher | : Karger Medical and Scientific Publishers |
Total Pages | : 200 |
Release | : 2012 |
Genre | : Medical |
ISBN | : 3805598025 |
How current biomarkers are modernizing the diagnosis of Alzheimer's disease Expanding knowledge on genetic and epigenetic risk factors is rapidly enhancing our understanding of the complex molecular interactions and systems involved in the pathogenesis of Alzheimer's disease. In this publication, leading experts discuss emerging novel conceptual models of the disease along with advances in the development of surrogate markers that will not only improve the accuracy of diagnostic technologies but also improve the prospects of developing disease-modifying interventions. The novel framework of the disease presented here highlights research on biological markers as well as efforts to validate technologies for early and accurate detection. It also introduces notion of a complex systems dysfunction that extends beyond prevailing ideas derived from the amyloid' or tau' hypotheses. This outstanding publication provides researchers, clinicians, students and other professionals interested in neurodegenerative disorders with a comprehensive update on current trends and future directions in therapy development, with special focus on advances in clinical trial designs.
Author | : M. Briley |
Publisher | : |
Total Pages | : 308 |
Release | : 1986 |
Genre | : Alzheimer's disease |
ISBN | : 9780333413562 |
Author | : Amy Borenstein |
Publisher | : Academic Press |
Total Pages | : 467 |
Release | : 2016-02-16 |
Genre | : Psychology |
ISBN | : 0124171540 |
Alzheimer's Disease: Lifecourse Perspectives on Risk Reduction summarizes the growing body of knowledge on the distribution and causes of Alzheimer's disease (AD) in human populations, providing the reader with knowledge on how we define the disease and what its risk and protective factors are in the context of a life-course approach. At the conclusion of the book, the reader will understand why Alzheimer's disease likely begins at conception, then progresses through early-life and adult risk factors that ultimately impact the balance between pathologic insults in the brain and the ability of the brain to modify disease symptoms. In contrast to edited volumes that may have little cohesion, this book focuses on an integrated life-course approach to the epidemiology of dementia, in particular, Alzheimer's disease. - Reviews the current science surrounding Alzheimer's disease - Provides a primer of foundational knowledge on the disease's epidemiology and biostatistics - Utilizes a life-course approach, providing a novel and integrated view of the evolution of this illness from genes to brain reserve - Uses the 'threshold model'—a theory first described by Dr. Mortimer and widely accepted today—which incorporates the idea of risk factors for the pathology and expression of the disease - Proposes that improving brain health through modifiable behaviors can delay disease onset until a later age - Examines the future of prevention of Alzheimer's disease, a subject of great current interest
Author | : Ronald C. Petersen |
Publisher | : Oxford University Press |
Total Pages | : 286 |
Release | : 2003-01-09 |
Genre | : Medical |
ISBN | : 0198028741 |
What are the boundary zones between normal aging and Alzheimer's disease (AD)? Are many elderly people whom we regard as normal actually in the early stages of AD? Alzheimer's disease does not develop overnight; the early phases may last for years or even decades. Recently, clinical investigators have identified a transitional condition between normal aging and and very early Alzheimer's disease that they have called mild cognitive impairment, or MCI. This term typically refers to memory impairment beyond what one would expect in individuals of a given age whose other abilities to function in daily life are well preserved. Persons who meet the criteria for mild cognitive impairment have an increased risk of progressing to Alzheimer's disease in the near future. Though many questions about this condition and its underlying neuropathology remain open, full clinical trials are currently underway worldwide aimed at preventing the progression from MCI to Alzheimer's disease. This book addresses the spectrum of issues involved in mild cognitive impairment, and includes chapters on clinical studies, neuropsychology, neuroimaging, neuropathology, biological markers, diagnostic approaches, and treatment. It is intended for clinicians, researchers, and students interested in aging and cognition, among them neurologists, psychiatrists, geriatricians, clinical psychologists, and neuropsychologists.
Author | : M.C. Carrillo |
Publisher | : Karger Medical and Scientific Publishers |
Total Pages | : 200 |
Release | : 2012-04-23 |
Genre | : Medical |
ISBN | : 3805598033 |
Expanding knowledge on genetic and epigenetic risk factors is rapidly enhancing our understanding of the complex molecular interactions and systems involved in the pathogenesis of Alzheimer’s disease. In this publication, leading experts discuss emerging novel conceptual models of the disease along with advances in the development of surrogate markers that will not only improve the accuracy of diagnostic technologies but also improve the prospects of developing disease-modifying interventions. The novel framework of the disease presented here highlights research on biological markers as well as efforts to validate technologies for early and accurate detection. It also introduces notion of a complex systems dysfunction that extends beyond prevailing ideas derived from the ‘amyloid’ or ‘tau’ hypotheses.This outstanding publication provides researchers, clinicians, students and other professionals interested in neurodegenerative disorders with a comprehensive update on current trends and future directions in therapy development, with special focus on advances in clinical trial designs.
Author | : Robert J. Dillmann |
Publisher | : |
Total Pages | : 357 |
Release | : 1990 |
Genre | : Alzheimer's disease |
ISBN | : 9789051700435 |
Author | : Walter George Bradley |
Publisher | : |
Total Pages | : 1672 |
Release | : 2004 |
Genre | : Medical |
ISBN | : 9780750674690 |
New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.
Author | : Peter J. Whitehouse, M.D. |
Publisher | : Macmillan |
Total Pages | : 336 |
Release | : 2008-12-09 |
Genre | : Health & Fitness |
ISBN | : 0312368178 |
Challenges conventional perceptions about Alzheimer's disease to offer readers alternative approaches to memory loss and aging that can be aided through simple nutritional and exercise strategies.
Author | : Suzanne De La Monte |
Publisher | : BoD – Books on Demand |
Total Pages | : 706 |
Release | : 2011-09-12 |
Genre | : Medical |
ISBN | : 9533076909 |
Alzheimer's Disease Pathogenesis: Core Concepts, Shifting Paradigms, and Therapeutic Targets, delivers the concepts embodied within its title. This exciting book presents the full array of theories about the causes of Alzheimer's, including fresh concepts that have gained ground among both professionals and the lay public. Acknowledged experts provide highly informative yet critical reviews of the factors that most likely contribute to Alzheimer's, including genetics, metabolic deficiencies, oxidative stress, and possibly environmental exposures. Evidence that Alzheimer's resembles a brain form of diabetes is discussed from different perspectives, ranging from disease mechanisms to therapeutics. This book is further energized by discussions of how neurotransmitter deficits, neuro-inflammation, and oxidative stress impair neuronal plasticity and contribute to Alzheimer's neurodegeneration. The diversity of topics presented in just the right depth will interest clinicians and researchers alike. This book inspires confidence that effective treatments could be developed based upon the expanding list of potential therapeutic targets.