Irreversible Electroporation

Irreversible Electroporation
Author: Boris Rubinsky
Publisher: Springer Science & Business Media
Total Pages: 320
Release: 2009-11-25
Genre: Technology & Engineering
ISBN: 364205420X

Non-thermal irreversible electroporation is a new minimally invasive surgical p- cedure with unique molecular selectivity attributes – in fact it may be considered the first clinical molecular surgery procedure. Non-thermal irreversible electro- ration is a molecular selective mode of cell ablation that employs brief electrical fields to produce nanoscale defects in the cell membrane, which can lead to cell death, without an effect on any of the other tissue molecules. The electrical fields can be produced through contact by insertion of electrode needles around the undesirable tissue and non-invasively by electromagnetic induction. This new - dition to the medical armamentarium requires the active involvement and is of interest to clinical physicians, medical researchers, mechanical engineers, che- cal engineers, electrical engineers, instrumentation designers, medical companies and many other fields and disciplines that were never exposed in their training to irreversible electroporation or to a similar concept. This edited book is designed to be a comprehensive introduction to the field of irreversible electroporation to those that were not exposed or trained in the field before and can also serve as a reference manual. Irreversible electroporation is broad and interdisciplinary. Therefore, we have made an attempt to cover every one of the various aspects of the field from an introductory basic level to state of the art.

MRI-Guided Focused Ultrasound Surgery

MRI-Guided Focused Ultrasound Surgery
Author: Ferenc A. Jolesz
Publisher: CRC Press
Total Pages: 217
Release: 2007-09-26
Genre: Medical
ISBN: 1420019937

MRI-Guided Focused Ultrasound Surgery will be the first publication on this new technology, and will present a variety of current and future clinical applications in tumor ablation treatment. This source helps surgeons and specialists evaluate, analyze, and utilize MRI-guided focused ultrasound surgery - bridging the gap between phase 3 clinical tr

Nanomaterials for Magnetic and Optical Hyperthermia Applications

Nanomaterials for Magnetic and Optical Hyperthermia Applications
Author: Raluca Maria Fratila
Publisher: Elsevier
Total Pages: 386
Release: 2018-11-30
Genre: Science
ISBN: 0128139293

Nanomaterials for Magnetic and Optical Hyperthermia Applications focuses on the design, fabrication and characterization of nanomaterials (magnetic, gold and hybrid magnetic-gold nanoparticles) for in vitro and in vivo hyperthermia applications, both as standalone and adjuvant therapy in combination with chemotherapy. The book explores the potential for more effective cancer therapy solutions through the synergistic use of nanostructured materials as magnetic and optical hyperthermia agents and targeted drug delivery vehicles, while also discussing the challenges related to their toxicity, regulatory and translational aspects. In particular, the book focuses on the design, synthesis, biofunctionalization and characterization of nanomaterials employed for magnetic and optical hyperthermia. This book will be an important reference resource for scientists working in the areas of biomaterials and biomedicine seeking to learn about the potential of nanomaterials to provide hyperthermia solutions. - Explores the design of efficient nanomaterials for hyperthermia applications, allowing readers to make informed materials selection decisions - Discusses the biofunctionalization of a range of nanomaterials and their interaction with living systems - Provides an overview of the current clinical applications of nanomaterials in hyperthermia treatment

Thermal Ablation Therapy

Thermal Ablation Therapy
Author: Amira S. Ashour
Publisher: Elsevier
Total Pages: 466
Release: 2021-05-21
Genre: Science
ISBN: 0128195444

Thermal Ablation Therapy: Theory and Simulation includes detailed theoretical and technical concepts of thermal ablation therapy in different body organs. Concepts of ablation technology based on different thermal ablation methods are introduced, along with changes in the tissues' mechanical properties due to thermal denaturation. The book emphasizes the mathematical and engineering concepts of RF and MW energy propagation through tissues and where high heating rates produced by MW systems can overcome the heat-sink effects from nearby vessels. The design and tuning of the MW antennas to deliver energy efficiently to specific organ systems such as the liver or lung is also covered. Other sections cover the computational modeling of radiofrequency ablation and microwave ablation procedures for developing and implementing new efficient ablation in clinical systems, numerical simulations for different scenarios of different organs with different size using RF and MW ablation systems with different antennas'/probes design and configurations, and numerical techniques for temperature profile in tissues. Presents the latest mathematical models of microwave and RF ablation theories Discusses the biological responses and engineering principles by which thermal ablation techniques can provide temperature-elevation within the organs of the human body, including action mechanisms, required equipment, needle characteristics and treatment techniques Highlights the different techniques of thermal ablation, including radiofrequency ablation, microwave ablation, laser ablation, and ultrasound ablation, nanotechnology, and the different metrics used to evaluate the performance of the used antenna within the ablation needle

Minimally Invasive Tumor Therapies

Minimally Invasive Tumor Therapies
Author: C. Stroszczynski
Publisher: Springer Science & Business Media
Total Pages: 146
Release: 2006-09-09
Genre: Medical
ISBN: 3540281371

In the age of the World Wide Web, informed patients continue to surprise oncologists with detailed questions about popular tumor therapies. Although minimally invasive tumor therapies (MITT) have become daily clinical practice for palliative treatment of liver tumors, the acceptance of these palliative modalities still varies enormously. This book gives an up-to-date overview of the popular techniques and clinical results of MITT, with a clarification of the actual indications including the size, tumor entities, and clinical benefits. Moreover, the book focuses on the prospectives and limitations of imaging methods used for MITT.

RF / Microwave Interaction with Biological Tissues

RF / Microwave Interaction with Biological Tissues
Author: André Vander Vorst
Publisher: John Wiley & Sons
Total Pages: 346
Release: 2006-02-06
Genre: Technology & Engineering
ISBN: 0471752045

From engineering fundamentals to cutting-edge clinical applications This book examines the biological effects of RF/microwaves and their medical applications. Readers will discover new developments in therapeutic applications in such areas as cardiology, urology, surgery, ophthalmology, and oncology. The authors also present developing applications in such areas as cancer detection and organ imaging. Focusing on frequency ranges from 100 kHz to 10 GHz, RF/Microwave Interaction with Biological Tissues is divided into six chapters: * Fundamentals in Electromagnetics--examines penetration of RF/microwaves into biological tissues; skin effect; relaxation effects in materials and the Cole-Cole model (display); the near field of an antenna; blackbody radiation and the various associated laws; and microwave measurements. * RF/Microwave Interaction Mechanisms in Biological Materials--includes a section devoted to the fundamentals of thermodynamics and a discussion on energy and entropy. * Biological Effects--investigates the effects of radio frequency fields on the nervous system, the brain and spinal cord, the blood-brain barrier, and cells and membranes. * Thermal Therapy--includes a description of applicators and an extensive discussion on the foundation of dielectric heating and inductive heating. * EM-Wave Absorbers Protecting the Biological and Medical Environment--investigates materials for EM-wave absorbers from both a theoretical and applications perspective. Special attention is given to ferrite absorbers. * RF/Microwave Delivery Systems for Therapeutic Applications--begins with the fundamental features of major components used in RF/microwave delivery systems for therapeutic applications. New research towards the development of future measurement techniques is also presented. The book features problem sets at the end of each chapter, making it an excellent introduction for bioengineering and engineering students. Researchers, physicians, and technicians in the field will also find this an excellent reference that offers all the fundamentals, the most cutting-edge applications, and insight into future developments. An Instructor's Manual presenting detailed solutions to all the problems in the book is available from the Wiley editorial department.

Clinical Aspects of Electroporation

Clinical Aspects of Electroporation
Author: Stephen T. Kee
Publisher: Springer Science & Business Media
Total Pages: 251
Release: 2011-04-06
Genre: Medical
ISBN: 1441983635

Electroporation is the forefront in tumor ablation. This book presents the basic principles and clinical applications of electroporation, including the latest research results and patient data. A comprehensive approach to the basic science behind the development of this ground-breaking technique and its introduction into clinical practice, the book discusses the entire spectrum of currently available reversible treatments, the emerging irreversible applications, and their impact on patient care. Clinical Aspects of Electroporation is the first book intended for clinicians on this extremely important and rapidly developing field.

Advanced Healthcare Materials

Advanced Healthcare Materials
Author: Ashutosh Tiwari
Publisher: John Wiley & Sons
Total Pages: 421
Release: 2014-05-09
Genre: Technology & Engineering
ISBN: 1118773683

Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers

Medical Image Computing and Computer-Assisted Intervention - MICCAI 2002

Medical Image Computing and Computer-Assisted Intervention - MICCAI 2002
Author: Takeyoshi Dohi
Publisher: Springer
Total Pages: 855
Release: 2003-06-30
Genre: Computers
ISBN: 3540457860

The fifth international Conference in Medical Image Computing and Computer Assisted Intervention (MICCAI 2002) was held in Tokyo from September 25th to 28th, 2002. This was the first time that the conference was held in Asia since its foundation in 1998. The objective of the conference is to offer clinicians and scientists the opportunity to collaboratively create and explore the new medical field. Specifically, MICCAI offers a forum for the discussion of the state of art in computer-assisted interventions, medical robotics, and image processing among experts from multi-disciplinary professions, including but not limited to clinical doctors, computer scientists, and mechanical and biomedical engineers. The expectations of society are very high; the advancement of medicine will depend on computer and device technology in coming decades, as they did in the last decades. We received 321 manuscripts, of which 41 were chosen for oral presentation and 143 for poster presentation. Each paper has been included in these proceedings in eight-page full paper format, without any differentiation between oral and poster papers. Adherence to this full paper format, along with the increased number of manuscripts, surpassing all our expectations, has led us to issue two proceedings volumes for the first time in MICCAI’s history. Keeping to a single volume by assigning fewer pages to each paper was certainly an option for us considering our budget constraints. However, we decided to increase the volume to offer authors maximum opportunity to argue the state of art in their work and to initiate constructive discussions among the MICCAI audience.