Biomaterials Science

Biomaterials Science
Author: Buddy D. Ratner
Publisher: Elsevier
Total Pages: 879
Release: 2004-08-18
Genre: Technology & Engineering
ISBN: 008047036X

The second edition of this bestselling title provides the most up-to-date comprehensive review of all aspects of biomaterials science by providing a balanced, insightful approach to learning biomaterials. This reference integrates a historical perspective of materials engineering principles with biological interactions of biomaterials. Also provided within are regulatory and ethical issues in addition to future directions of the field, and a state-of-the-art update of medical and biotechnological applications. All aspects of biomaterials science are thoroughly addressed, from tissue engineering to cochlear prostheses and drug delivery systems. Over 80 contributors from academia, government and industry detail the principles of cell biology, immunology, and pathology. Focus within pertains to the clinical uses of biomaterials as components in implants, devices, and artificial organs. This reference also touches upon their uses in biotechnology as well as the characterization of the physical, chemical, biochemical and surface properties of these materials. - Provides comprehensive coverage of principles and applications of all classes of biomaterials - Integrates concepts of biomaterials science and biological interactions with clinical science and societal issues including law, regulation, and ethics - Discusses successes and failures of biomaterials applications in clinical medicine and the future directions of the field - Cover the broad spectrum of biomaterial compositions including polymers, metals, ceramics, glasses, carbons, natural materials, and composites - Endorsed by the Society for Biomaterials

UHMWPE Biomaterials Handbook

UHMWPE Biomaterials Handbook
Author: Steven M. Kurtz
Publisher: Academic Press
Total Pages: 564
Release: 2009-04-27
Genre: Technology & Engineering
ISBN: 008088444X

UHMWPE Biomaterials Handbook describes the science, development, properties and application of of ultra-high molecular weight polyethylene (UHMWPE) used in artificial joints. This material is currently used in 1.4 million patients around the world every year for use in the hip, knee, upper extremities, and spine. Since the publication of the 1st edition there have been major advances in the development and clinical adoption of highly crosslinked UHMWPE for hip and knee replacement. There has also been a major international effort to introduce Vitamin E stabilized UHMWPE for patients. The accumulated knowledge on these two classes of materials are a key feature of the 2nd edition, along with an additional 19 additional chapters providing coverage of the key engineering aspects (biomechanical and materials science) and clinical/biological performance of UHMWPE, providing a more complete reference for industrial and academic materials specialists, and for surgeons and clinicians who require an understanding of the biomaterials properties of UHMWPE to work successfully on patient applications. - The UHMWPE Handbook is the comprehensive reference for professionals, researchers, and clinicians working with biomaterials technologies for joint replacement - New to this edition: 19 new chapters keep readers up to date with this fast moving topic, including a new section on UHMWPE biomaterials; highly crosslinked UHMWPE for hip and knee replacement; Vitamin E stabilized UHMWPE for patients; clinical performance, tribology an biologic interaction of UHMWPE - State-of-the-art coverage of UHMWPE technology, orthopedic applications, biomaterial characterisation and engineering aspects from recognised leaders in the field

Wound Healing Biomaterials - Volume 1

Wound Healing Biomaterials - Volume 1
Author: Magnus Ågren
Publisher: Woodhead Publishing
Total Pages: 320
Release: 2016-06-03
Genre: Medical
ISBN: 0081006055

Wound Healing Biomaterials: Volume One, Therapies and Regeneration discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal these types of wounds, with science increasingly turning towards biomaterials to address these challenges. Much research is now concerned with new therapies, regeneration methods, and biomaterials to assist in wound healing and healing response. This book provides readers with a comprehensive review of the fundamentals and advances in the field of wound healing with regard to therapies and tissue regeneration. Chapters in Part One discuss fundamentals and strategies of wound healing, while Part Two reviews gene, stem cell, and drug delivery therapies for wound healing. Final chapters look at tissue regeneration strategies, making this an all-encompassing book on the topic of wound care and biomaterials. - Provides more systematic and comprehensive coverage of specific therapies and biomaterials for wound healing - Highlights research that is concerned with new therapies, regeneration methods, and the use of biomaterials to assist in wound healing and healing response - Presents an organized layout of the material that is carefully arranged with clear titles and comprehensive section headings - Looks at tissue regeneration strategies, making this an all encompassing book on the topic of wound care

Introductory Biomaterials

Introductory Biomaterials
Author: Lia Stanciu
Publisher: Academic Press
Total Pages: 369
Release: 2021-09-23
Genre: Medical
ISBN: 0128095245

Introductory Biomaterials enables undergraduate students in Biomedical, Chemical, Materials and other relevant Engineering disciplines to become familiar with the key concepts of Biomaterials principles: biocompatibility, structure-property-applications relationships, mechanical response of natural tissues, and cellular pathways for tissue-material ingrowth. Written in a clear, concise manner that weds theory with applications, this book helps students to understand the often intricate relationships between materials the implant devices that are made from them, and how the human body reacts to them. The book includes such concepts as requirements for metals, alloys, and ceramic materials to be used in load bearing implants (corrosion concepts, stress shielding, mechanical properties, composition), what properties of polymers impact their use in medicine (leaching and swelling, creep and stress relaxation); the tissue response to biomaterials, concepts related to drug delivery applications (polymer degradation, encapsulation), and tissue engineering (scaffold porosity, diffusion of nutrients, mechanical properties). - Begins with structure-properties, followed immediately by their impact on actual biomaterials classes and devices, thus directly relating theory to applications (e.g. polymers to polymeric stents; metals to fracture fixation devices) - Explains concepts in a clear, progressive manner, with numerous examples and figures to enhance student learning - Covers all key biomaterials classes: metallic, ceramic, polymeric, composite and biological - Includes a timely chapter on medical device regulation

Self-assembling Biomaterials

Self-assembling Biomaterials
Author: Helena S. Azevedo
Publisher: Woodhead Publishing
Total Pages: 614
Release: 2018-04-17
Genre: Technology & Engineering
ISBN: 0081020120

Self-assembling biomaterials: molecular design, characterization and application in biology and medicine provides a comprehensive coverage on an emerging area of biomaterials science, spanning from conceptual designs to advanced characterization tools and applications of self-assembling biomaterials, and compiling the recent developments in the field. Molecular self-assembly, the autonomous organization of molecules, is ubiquitous in living organisms and intrinsic to biological structures and function. Not surprisingly, the exciting field of engineering artificial self-assembling biomaterials often finds inspiration in Biology. More important, materials that self-assemble speak the language of life and can be designed to seamlessly integrate with the biological environment, offering unique engineering opportunities in bionanotechnology. The book is divided in five parts, comprising design of molecular building blocks for self-assembly; exclusive features of self-assembling biomaterials; specific methods and techniques to predict, investigate and characterize self-assembly and formed assemblies; different approaches for controlling self-assembly across multiple length scales and the nano/micro/macroscopic properties of biomaterials; diverse range of applications in biomedicine, including drug delivery, theranostics, cell culture and tissue regeneration. Written by researchers working in self-assembling biomaterials, it addresses a specific need within the Biomaterials scientific community. - Explores both theoretical and practical aspects of self-assembly in biomaterials - Includes a dedicated section on characterization techniques, specific for self-assembling biomaterials - Examines the use of dynamic self-assembling biomaterials

PEEK Biomaterials Handbook

PEEK Biomaterials Handbook
Author: Steven M. Kurtz
Publisher: William Andrew
Total Pages: 309
Release: 2011-11-09
Genre: Medical
ISBN: 143774463X

PEEK biomaterials are currently used in thousands of spinal fusion patients around the world every year. Durability, biocompatibility and excellent resistance to aggressive sterilization procedures make PEEK a polymer of choice, replacing metal in orthopedic implants, from spinal implants and hip replacements to finger joints and dental implants. This Handbook brings together experts in many different facets related to PEEK clinical performance as well as in the areas of materials science, tribology, and biology to provide a complete reference for specialists in the field of plastics, biomaterials, medical device design and surgical applications. Steven Kurtz, author of the well respected UHMWPE Biomaterials Handbook and Director of the Implant Research Center at Drexel University, has developed a one-stop reference covering the processing and blending of PEEK, its properties and biotribology, and the expanding range of medical implants using PEEK: spinal implants, hip and knee replacement, etc. Covering materials science, tribology and applications Provides a complete reference for specialists in the field of plastics, biomaterials, biomedical engineering and medical device design and surgical applications

Definitions of Biomaterials for the Twenty-First Century

Definitions of Biomaterials for the Twenty-First Century
Author: Xingdong Zhang
Publisher: Elsevier
Total Pages: 292
Release: 2019-06-20
Genre: Technology & Engineering
ISBN: 012818292X

Definitions of Biomaterials for the Twenty-First Century is a review of key, critical biomaterial terms and definitions endorsed by the International Union of Societies for Biomaterials Science and Engineering. The topics and definitions discussed include those in general biomaterials and applications, biocompatibility, implantable and interventional devices, drug delivery systems, regenerative medicine and emerging biomaterials. The book reviews the discussion of these terms by leaders in the global biomaterials community and summarizes the agreed upon definitions. - Provides readers with the official definitions of critical biomaterials terms endorsed by the International Union of Societies for Biomaterials Science and Engineering - Includes the combined contributions from more than 50 global leaders in the biomaterials community - Updates terms based on the latest advances in clinical and scientific understanding and expanded scope of biomaterials science

The Chemistry of Medical and Dental Materials

The Chemistry of Medical and Dental Materials
Author: John W Nicholson
Publisher: Royal Society of Chemistry
Total Pages: 255
Release: 2007-10-31
Genre: Medical
ISBN: 1847552056

Implants into the human body, such as hip joints, heart valves and dental crowns, have been increasingly used over the last 40 years or so, and many patients have benefited from their use. But how much is known about the metals, ceramics and polymers that are used in these repairs? This book provides a state-of-the-art account of the chemistry of the synthetic materials used in medicine and dentistry. It looks at the properties and interactions of these materials within the body at a molecular level, and includes discussion of bioengineering and cell biology. In addition, there is an account of the surgical procedures used, as well as extensive coverage of the possible biological reactions to the presence of foreign materials in the body. A brief look at the emerging field of tissue engineering completes the text. Fully referenced, with detailed reviews of the current literature, The Chemistry of Medical and Dental Materials will be an essential starting-point for all those in academia and industry who are involved in the development of new and improved repair materials.

Wound Healing Biomaterials - Volume 2

Wound Healing Biomaterials - Volume 2
Author: Magnus Ågren
Publisher: Woodhead Publishing
Total Pages: 544
Release: 2016-05-30
Genre: Technology & Engineering
ISBN: 0081006063

Wound Healing Biomaterials: Volume Two, Functional Biomaterials discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal wounds opening up a new area of research in biomaterials and the ways they can be applied to the challenges associated with wound care. Much research is now concerned with new therapies, regeneration methods, and the use of biomaterials that can assist in wound healing and alter healing responses. This book provides readers with a thorough review of the functional biomaterials used for wound healing, with chapters discussing the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and functional dressings for wound care. - Includes more systematic and comprehensive coverage on the topic of wound care - Provides thorough coverage of all specific therapies and biomaterials for wound healing - Contains clear layout and organization that is carefully arranged with clear titles and comprehensive section headings - Details specific sections on the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and more

Renewable Resources for Functional Polymers and Biomaterials

Renewable Resources for Functional Polymers and Biomaterials
Author: Peter Williams
Publisher: Royal Society of Chemistry
Total Pages: 386
Release: 2015-11-09
Genre: Science
ISBN: 1782625844

This book details polysaccharides and other important biomacromolecules covering their source, production, structures, properties, and current and potential application in the fields of biotechnology and medicine. It includes a systematic discussion on the general strategies of isolation, separation and characterization of polysaccharides and proteins. Subsequent chapters are devoted to polysaccharides obtained from various sources, including botanical, algal, animal and microbial. In the area of botanical polysaccharides, separate chapters are devoted to the sources, structure, properties and medical applications of cellulose and its derivatives, starch and its derivatives, pectins, and exudate gums, notably gum arabic. Another chapter discusses the potential of hemicelluloses (xylans and xylan derivatives) as a new source of functional biopolymers for biomedical and industrial applications. The algal polysaccharide, alginate, has significant application in food, pharmaceuticals and the medical field, all of which are reviewed in a separate chapter. Polysaccharides of animal origin are included with separate chapters on the sources, production, biocompatibility, biodegradability and biomedical applications of chitin (chitosan) and hyaluronan. With the increasing knowledge and applications of genetic engineering there is also an introduction in the book to nucleic acid polymers, the genome research and genetic engineering. Proteins and protein conjugates are covered, with one chapter providing a general review of structural glycoproteins, fibronectin and laminin, together with their role in the promotion of cell adhesion in vascular grafts, implants and tissue engineering. Another chapter discusses general aspects of a number of industrial proteins, including casein, caseinates, whey protein, gluten and soy proteins, with emphasis on their medical applications, and with reference to the potential of bacterial proteins. Another natural polymer resource, microbial polyesters, although small compared with polysaccharides and proteins, is also gaining increasing interest in biomedical technology and other industrial sectors. One chapter, therefore, is devoted to microbial polyesters, with comprehensive coverage of their biosynthesis, properties, enzymic degradation and applications. By dealing with biopolymers at the molecular level, the book is aimed at the biomedical and wider materials science communities and provides an advanced overview of biopolymers at the graduate and postgraduate level. In addition it will appeal to both academic and industrial life scientists who are involved in research and development activities in the medical and biotechnology field.