Comparative Proteomics An Approach To Elucidating The Function Of A Novel Gene Called Bre
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Author | : Tsz Kwong Man |
Publisher | : IntechOpen |
Total Pages | : 452 |
Release | : 2012-02-10 |
Genre | : Science |
ISBN | : 9789533078328 |
Biomedical research has entered a new era of characterizing a disease or a protein on a global scale. In the post-genomic era, Proteomics now plays an increasingly important role in dissecting molecular functions of proteins and discovering biomarkers in human diseases. Mass spectrometry, two-dimensional gel electrophoresis, and high-density antibody and protein arrays are some of the most commonly used methods in the Proteomics field. This book covers four important and diverse areas of current proteomic research: Proteomic Discovery of Disease Biomarkers, Proteomic Analysis of Protein Functions, Proteomic Approaches to Dissecting Disease Processes, and Organelles and Secretome Proteomics. We believe that clinicians, students and laboratory researchers who are interested in Proteomics and its applications in the biomedical field will find this book useful and enlightening. The use of proteomic methods in studying proteins in various human diseases has become an essential part of biomedical research.
Author | : Kenneth Ka Ho Lee |
Publisher | : |
Total Pages | : |
Release | : 2012 |
Genre | : |
ISBN | : 9789533078328 |
Author | : Tsz Kwong Man |
Publisher | : BoD – Books on Demand |
Total Pages | : 454 |
Release | : 2012-02-10 |
Genre | : Science |
ISBN | : 9533078324 |
Biomedical research has entered a new era of characterizing a disease or a protein on a global scale. In the post-genomic era, Proteomics now plays an increasingly important role in dissecting molecular functions of proteins and discovering biomarkers in human diseases. Mass spectrometry, two-dimensional gel electrophoresis, and high-density antibody and protein arrays are some of the most commonly used methods in the Proteomics field. This book covers four important and diverse areas of current proteomic research: Proteomic Discovery of Disease Biomarkers, Proteomic Analysis of Protein Functions, Proteomic Approaches to Dissecting Disease Processes, and Organelles and Secretome Proteomics. We believe that clinicians, students and laboratory researchers who are interested in Proteomics and its applications in the biomedical field will find this book useful and enlightening. The use of proteomic methods in studying proteins in various human diseases has become an essential part of biomedical research.
Author | : Mahmood-Ur-Rahman Ansari |
Publisher | : BoD – Books on Demand |
Total Pages | : 91 |
Release | : 2018-07-18 |
Genre | : Science |
ISBN | : 1789233909 |
The chapters in this book are written by a team of well-reputed international researchers. The objective is to provide advanced and updated information related to protein-protein interactions. I hope the methods, resources and approaches described here will enhance the available knowledge of the reader significantly.
Author | : Rafael Trindade Maia |
Publisher | : BoD – Books on Demand |
Total Pages | : 147 |
Release | : 2021-03-10 |
Genre | : Science |
ISBN | : 1839628057 |
Homology modeling is an extremely useful and versatile technique that is gaining more and more space and demand in research in computational and theoretical biology. This book, “Homology Molecular Modeling - Perspectives and Applications”, brings together unpublished chapters on this technique. In this book, 7 chapters are intimately related to the theme of molecular modeling, carefully selected and edited for academic and scientific readers. It is an indispensable read for anyone interested in the areas of bioinformatics and computational biology. Divided into 4 sections, the reader will have a didactic and comprehensive view of the theme, with updated and relevant concepts on the subject. This book was organized from researchers to researchers with the aim of spreading the fascinating area of molecular modeling by homology.
Author | : Matthew Summers |
Publisher | : BoD – Books on Demand |
Total Pages | : 228 |
Release | : 2019-06-19 |
Genre | : Science |
ISBN | : 1838804900 |
The human ubiquitin proteasome system (UPS) is comprised of nearly 1000 proteins. Although originally identified as a mechanism of protein destruction, the UPS has numerous additional functions and mediates central signaling events in myriad processes involved in both cellular and organismal health and homeostasis. Numerous pathways within the UPS are implicated in disease, ranging from cancer to neurodegenerative diseases such as Parkinson's. The goal of this book is to deliver a collection of synopses of current areas of UPS research that highlights the importance of understanding the biology of the UPS to identify disease-relevant pathways, and the need to elucidate the molecular machinations within the UPS to develop methods for therapeutic modulation of these pathways.
Author | : Isil Aksan Kurnaz |
Publisher | : CRC Press |
Total Pages | : 334 |
Release | : 2015-05-08 |
Genre | : Medical |
ISBN | : 1482260905 |
Although designed for undergraduates with an interest in molecular biology, biotechnology, and bioengineering, this book-Techniques in Genetic Engineering-IS NOT: a laboratory manual; nor is it a textbook on molecular biology or biochemistry. There is some basic information in the appendices about core concepts such as DNA, RNA, protein, genes, and
Author | : Lucy W. Barrett |
Publisher | : Springer Science & Business Media |
Total Pages | : 63 |
Release | : 2013-06-26 |
Genre | : Science |
ISBN | : 3034806795 |
There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.
Author | : Andrew J. W. Orry |
Publisher | : Humana Press |
Total Pages | : 419 |
Release | : 2012-02-10 |
Genre | : Science |
ISBN | : 9781617795879 |
Knowledge about protein tertiary structure can guide experiments, assist in the understanding of structure-function relationships, and aid the design of new therapeutics for disease. Homology modeling is an in silico method that predicts the tertiary structure of an amino acid sequence based on a homologous experimentally determined structure. In, Homology Modelling: Methods and Protocols experts in the field describe each homology modeling step from first principles, provide case studies for challenging modeling targets and describe methods for the prediction of how other molecules such as drugs can interact with the protein. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Homology Modelling: Methods and Protocols guides scientists in the available homology modeling methods.
Author | : Parvaiz Ahmad |
Publisher | : Elsevier |
Total Pages | : 654 |
Release | : 2016-02-02 |
Genre | : Technology & Engineering |
ISBN | : 0128031832 |
Plant Metal Interaction: Emerging Remediation Techniques covers different heavy metals and their effect on soils and plants, along with the remediation techniques currently available. As cultivable land is declining day-by-day as a result of increased metals in our soil and water, there is an urgent need to remediate these effects. This multi-contributed book is divided into four sections covering the whole of plant metal interactions, including heavy metals, approaches to alleviate heavy metal stress, microbial approaches to remove heavy metals, and phytoremediation. Provides an overview of the effect of different heavy metals on growth, biochemical reactions, and physiology of various plants Serves as a reference guide for available techniques, challenges, and possible solutions in heavy metal remediation Covers sustainable technologies in uptake and removal of heavy metals