Synthetic Biology

Synthetic Biology
Author: Lewis D. Solomon
Publisher: Routledge
Total Pages: 153
Release: 2017-09-08
Genre: Science
ISBN: 135148723X

For nearly forty years, using recombinant DNA tools, researchers, and then businesses, have genetically engineered organisms by transferring naturally occurring genes from one organism into another. Doing so modifies the genetic code of living cells, imparting new traits and achieving desired results; this is done in the production of proteins, pharmaceuticals, and seeds. Synthetic biology, argues Solomon, could free scientists from the need to find natural genes to make such desired modifications. Synthetic biology permits more complex and sophisticated bioengineering than what can be achieved through previous genetic modification techniques. Drawing on non-biological scientific and engineering disciplines, including information technology and nanotechnology, synthetic biology strives to rearrange an organism's genes on a far wider scale by rewriting its genetic code, the chemical instructions need to design, assemble, and operate a species. By allowing the writing of artificial genetic codes, synthetic biology can transform existing industries and spawn new ones, creating new products as well as radically reshaping existing items. Arguing for self-regulation by the scientific and business communities, Lewis D. Solomon recommends a policy framework that would guard against governmental overregulation, which could create a barrier to innovation. Although synthetic biotechnology holds considerable social and economic potential, absent a nurturing regulatory climate, it may prove difficult to translate research discoveries into commercially viable applications.

Earth Grab

Earth Grab
Author: Diana Bronson
Publisher: Fahamu/Pambazuka
Total Pages: 182
Release: 2011-10-27
Genre: Business & Economics
ISBN: 0857490443

Exploiting the general public s growing concerns about the ecological and climate crisis, some corporations are proposing "quick fixes" that threaten to wreak havoc on our planet. This book exposes how a biomass economy, based on using gene technologies to reprogram living organisms, will devastate our ecosystems as well as the human populations of the southern hemisphereby accelerating the wave of land grabs already common in Africa, Asia, and Latin America. Well-researched and groundbreaking, this analysis explores a number ofinterrelated topicsvis-a-vis the uses of bio- and nano-technologies."

Synthetic Biology

Synthetic Biology
Author: Huimin Zhao
Publisher: Academic Press
Total Pages: 352
Release: 2013-03-21
Genre: Science
ISBN: 0123978203

Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. The roles of computers and computational design are discussed, as well as future prospects in the field, including cell-free synthetic biology and engineering synthetic ecosystems.Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems. - Includes contributions from leaders in the field presents examples of ambitious synthetic biology efforts including creation of artificial cells from scratch, cell-free synthesis of chemicals, fuels, and proteins, engineering of artificial photosynthesis for biofuels production, and creation of unnatural living organisms - Describes the latest state-of-the-art tools developed for low-cost synthesis of ever-increasing sizes of DNA and efficient modification of proteins, pathways, and genomes - Highlights key technologies for analyzing biological systems at the genomic, proteomic, and metabolomic levels which are especially valuable in pathway, whole cell, and multi-cell applications - Details mathematical modeling tools and computational tools which can dramatically increase the speed of the design process as well as reduce the cost of development

LabOratory

LabOratory
Author: Sandra Kaji-O'Grady
Publisher: MIT Press
Total Pages: 361
Release: 2024-02-06
Genre: Design
ISBN: 0262551136

An illustrated examination of laboratory architecture and the work that it does to engage the public, recruit scientists, and attract funding. The laboratory building is as significant to the twenty-first century as the cathedral was to the thirteenth and fourteenth centuries. The contemporary science laboratory is built at the grand scales of cathedrals and constitutes as significant an architectural statement. The laboratory is a serious investment in architectural expression in an attempt to persuade us of the value of the science that goes on inside. In this lavishly illustrated book, Sandra Kaji-O'Grady and Chris L. Smith explore the architecture of modern life science laboratories, and the work that it does to engage the public, recruit scientists, and attract funding. Looking at the varied designs of eleven important laboratories in North America, Europe, and Australia, all built between 2005 and 2019, Kaji-O'Grady and Smith examine the relationship between the design of contemporary laboratory buildings and the ideas and ideologies of science. Observing that every laboratory architect and client declares the same three aspirations—to eliminate boundaries, to communicate the benefits of its research programs, and to foster collaboration—Kaji-O'Grady and Smith organize their account according to the themes of boundaries, expression, and socialization. For instance, they point to the South Australian Health and Medical Institute's translucent envelope as the material equivalent of institutional accountability; the insistent animal imagery of the NavarraBioMed laboratory in Spain; and the Hillside Research Campus's mimicry of the picturesque fishing village that once occupied its site. Through these and their other examples, Kaji-O'Grady and Smith show how the architecture of the laboratory shapes the science that takes place within it.

Regenesis

Regenesis
Author: George M Church
Publisher: Basic Books
Total Pages: 305
Release: 2014-04-08
Genre: Science
ISBN: 0465038654

A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies-far from the out-of-control nightmare depicted in science fiction-have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

Synthetic Biology

Synthetic Biology
Author: Gigi Gronvall
Publisher: Createspace Independent Publishing Platform
Total Pages: 198
Release: 2016-10-08
Genre:
ISBN: 9781539336839

Synthetic biology aims to make biology easier to engineer and to program. Thanks to advances in computing power, the ability to make long tracts of DNA, new tools like CRISPR that can be used to edit genomes, and the enthusiasm of young scientists and even amateurs who want to enter the field, synthetic biology is poised to change the future of medicine, agriculture, and manufacturing. Yet, while this new field promises vast opportunities and benefits, there are also risks. There are biosecurity risks that these technologies will be deliberately used for harm; safety risks to people and the environment; ethical and social considerations for how to apply these technologies; and there are risks to the competitiveness of nations that do not invest in these technologies that are likely to spur economic growth. This volume is dedicated to a discussion of what can be done to minimize risks and maximize the benefits of synthetic biology. Praise for Synthetic Biology: Safety, Security, and Promise "There can be no doubt that advances in the life sciences, including new insights and tools provided by synthetic biology, place us in a position to create exciting and novel products and approaches for patients in need. Gigi Gronvall describes that promise but also lays forth critical policy concerns that need to be addressed so that we don't risk safety, security, or the competitiveness of US science." - Margaret Hamburg, MD, Former FDA Commissioner and Foreign Secretary, National Academy of Medicine "Synthetic biology gives us tools that can help tackle global problems that affect humanity-but for that to happen, the risks of bioterror or bio-error need to be dealt with and managed, as well. Gronvall clearly describes the policy challenges that must be addressed and concludes with steps to enhance US leadership and competitiveness in the global bio-economy." - J. Craig Venter, PhD, founder, chairman, and CEO of the J. Craig Venter Institute and co-founder, executive chairman and co-chief scientist of Synthetic Genomics, Inc. "For those of us working in the lab, it is important to embrace conversations with those who aren't - including strategies for biological security, to create new synthetic biology products - with respect for facts about GMO risk/benefit balances, creating a culture of safe lab practices and norms worldwide. Gigi Gronvall dissects such issues at stake in synthetic biology and presents a pragmatic and scientifically responsive path forward for anyone in a position to influence, regulate, decide upon, or benefit from the science to follow." - George Church, PhD, Professor of Genetics Harvard Medical School and Director of PersonalGenomes.org "Synthetic biology presents some of the greatest challenges and opportunities of the 21st Century. Gigi Gronvall navigates a path to follow, to make sure risks are addressed and opportunities are not squandered. It should be read by all concerned about national security." - The Honorable Andrew Weber, head of global partnerships for Metabiota and former Assistant Secretary of Defense for Nuclear, Chemical, and Biological Defense Programs

Intellectual Property and Emerging Technologies

Intellectual Property and Emerging Technologies
Author: Matthew Rimmer
Publisher: Edward Elgar Publishing
Total Pages: 499
Release: 2012-01-01
Genre: Technology & Engineering
ISBN: 1781001189

This unique and comprehensive collection investigates the challenges posed to intellectual property by recent paradigm shifts in biology. It explores the legal ramifications of emerging technologies, such as genomics, synthetic biology, stem cell research, nanotechnology, and biodiscovery. Extensive contributions examine recent controversial court decisions in patent law such as Bilski v. Kappos, and the litigation over Myriad's patents in respect of BRCA1 and BRCA2 while other papers explore sui generis fields, such as access to genetic resources, plant breeders' rights, and traditional knowledge. The collection considers the potential and the risks of the new biology for global challenges such as access to health-care, the protection of the environment and biodiversity, climate change, and food security. It also considers Big Science projects such as biobanks, the 1000 Genomes Project, and the Doomsday Vault. The inter-disciplinary research brings together the work of scholars from Australia, Canada, Europe, the UK and the US and involves not only legal analysis of case law and policy developments, but also historical, comparative, sociological, and ethical methodologies. Intellectual Property and Emerging Technologies will appeal to policy-makers, legal practitioners, business managers, inventors, scientists and researchers.

The Science of Algal Fuels

The Science of Algal Fuels
Author: Richard Gordon
Publisher: Springer Science & Business Media
Total Pages: 517
Release: 2012-12-04
Genre: Science
ISBN: 9400751109

This volume, The Science of Algal Fuels (volume 25 of COLE), contains 26 chapters dealing with biofuels contributed by experts from numerous countries and covers several aspects of algal products, one being “oilgae from algae,” mainly oils and fuels for engines. Among the prominent algal groups that participate in this process are the diatoms and green algae (Chlorophyceae). Their metabolism and breeding play an important role in biomass and extraction of crude oil and algal fuel. There is a strong relation between solar energy influencing algal culture and the photobiology of lipid metabolism. Currently, many international meetings and conferences on biofuel are taking place in many countries, and several new books and proceedings of conferences have appeared on this topic. All this indicates that this field is “hot” and in the forefront of applied bioscience.

Life at the Speed of Light

Life at the Speed of Light
Author: J. Craig Venter
Publisher: Penguin
Total Pages: 239
Release: 2014-09-30
Genre: Science
ISBN: 0143125907

“Venter instills awe for biology as it is, and as it might become in our hands.” —Publishers Weekly On May 20, 2010, headlines around the world announced one of the most extraordinary accomplishments in modern science: the creation of the world’s first synthetic lifeform. In Life at the Speed of Light, scientist J. Craig Venter, best known for sequencing the human genome, shares the dramatic account of how he led a team of researchers in this pioneering effort in synthetic genomics—and how that work will have a profound impact on our existence in the years to come. This is a fascinating and authoritative study that provides readers an opportunity to ponder afresh the age-old question “What is life?” at the dawn of a new era of biological engineering.