The Prevention and Treatment of Missing Data in Clinical Trials

The Prevention and Treatment of Missing Data in Clinical Trials
Author: National Research Council
Publisher: National Academies Press
Total Pages: 163
Release: 2010-12-21
Genre: Medical
ISBN: 030918651X

Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.

Evidence-based Diabetes Care

Evidence-based Diabetes Care
Author: Hertzel C. Gerstein
Publisher: PMPH-USA
Total Pages: 600
Release: 2001
Genre: Health & Fitness
ISBN: 9781550091243

Evidence-Based Diabetes Care is designed to help clarify the strengths and weaknesses upon which current clinical practice is based. This is a valuable source of important, up-to-date information for all clinicians and researches concerned with improving the quality of life of those affected by diabetes and its subsequent complications. Comprehensive commentary encompasses the areas of diabetes epidemiology, assessment of diagnostic tests, and development and assessment of management options.

Handbook of Statistical Data Editing and Imputation

Handbook of Statistical Data Editing and Imputation
Author: Ton de Waal
Publisher: John Wiley & Sons
Total Pages: 453
Release: 2011-03-04
Genre: Mathematics
ISBN: 0470904836

A practical, one-stop reference on the theory and applications of statistical data editing and imputation techniques Collected survey data are vulnerable to error. In particular, the data collection stage is a potential source of errors and missing values. As a result, the important role of statistical data editing, and the amount of resources involved, has motivated considerable research efforts to enhance the efficiency and effectiveness of this process. Handbook of Statistical Data Editing and Imputation equips readers with the essential statistical procedures for detecting and correcting inconsistencies and filling in missing values with estimates. The authors supply an easily accessible treatment of the existing methodology in this field, featuring an overview of common errors encountered in practice and techniques for resolving these issues. The book begins with an overview of methods and strategies for statistical data editing and imputation. Subsequent chapters provide detailed treatment of the central theoretical methods and modern applications, with topics of coverage including: Localization of errors in continuous data, with an outline of selective editing strategies, automatic editing for systematic and random errors, and other relevant state-of-the-art methods Extensions of automatic editing to categorical data and integer data The basic framework for imputation, with a breakdown of key methods and models and a comparison of imputation with the weighting approach to correct for missing values More advanced imputation methods, including imputation under edit restraints Throughout the book, the treatment of each topic is presented in a uniform fashion. Following an introduction, each chapter presents the key theories and formulas underlying the topic and then illustrates common applications. The discussion concludes with a summary of the main concepts and a real-world example that incorporates realistic data along with professional insight into common challenges and best practices. Handbook of Statistical Data Editing and Imputation is an essential reference for survey researchers working in the fields of business, economics, government, and the social sciences who gather, analyze, and draw results from data. It is also a suitable supplement for courses on survey methods at the upper-undergraduate and graduate levels.

Psychosocial Care for People with Diabetes

Psychosocial Care for People with Diabetes
Author: Deborah Young-Hyman
Publisher: American Diabetes Association
Total Pages: 330
Release: 2012-12-25
Genre: Psychology
ISBN: 1580404391

Psychosocial Care for People with Diabetes describes the major psychosocial issues which impact living with and self-management of diabetes and its related diseases, and provides treatment recommendations based on proven interventions and expert opinion. The book is comprehensive and provides the practitioner with guidelines to access and prescribe treatment for psychosocial problems commonly associated with living with diabetes.

Global Report on Diabetes

Global Report on Diabetes
Author: Gojka Roglic
Publisher:
Total Pages: 0
Release: 2016
Genre: Medical
ISBN: 9789241565257

"On the occasion of World Health Day 2016, WHO issues a call for action on diabetes, drawing attention to the need to step up prevention and treatment of the disease. The first WHO Global report on diabetes demonstrates that the number of adults living with diabetes has almost quadrupled since 1980 to 422 million adults. This dramatic rise is largely due to the rise in type 2 diabetes and factors driving it include overweight and obesity. In 2012 alone diabetes caused 1.5 million deaths. Its complications can lead to heart attack, stroke, blindness, kidney failure and lower limb amputation. The new report calls upon governments to ensure that people are able to make healthy choices and that health systems are able to diagnose, treat and care for people with diabetes. It encourages us all as individuals to eat healthily, be physically active, and avoid excessive weight gain."--Publisher's description.

Better Feedback for Better Teaching

Better Feedback for Better Teaching
Author: Jeff Archer
Publisher: John Wiley & Sons
Total Pages: 391
Release: 2016-04-25
Genre: Education
ISBN: 1118701984

A practical, research-based guide for ensuring trustworthy classroom observations that provide teachers with meaningful feedback Better Feedback for Better Teaching is an essential resource for school, district, and state, leaders committed to high-quality classroom observations. This practical guide outlines the knowledge and skills classroom observers need to identify and help develop effective teaching, and explains how leaders can best facilitate the development of classroom observers. The best way to ensure high quality instruction in every classroom is to provide teachers with accurate, constructive feedback on practices proven to enhance student learning. Skilled classroom observers help teachers do their best work, so that they can guide students to their greatest potential. Better Feedback for Better Teaching provides helpful, reliable strategies from leading experts and practitioners involved in the Measures of Effective Teaching (MET) project, which carried out one of the largest, most influential studies of classroom observations to date. Among the many topics covered, Better Feedback for Better Teaching describes how to: Build a shared vision of effective teacher feedback among observers Ensure a common understanding of a classroom observation tool Train observers to collect objective evidence from a lesson, efficiently and free of bias Leverage data to improve how observers are trained and supported This comprehensive resource includes helpful starting points, as well as tips to refine techniques and address new challenges. Each section combines clear explanations of key ideas with concrete, adaptable examples and strategies. Self-assessments are included to help you quickly rank current needs and find the most relevant solutions. Filled with valuable, practical tools, Better Feedback for Better Teaching helps educators cultivate high-quality classroom observations that improve teaching and learning.

Older Mexican Americans

Older Mexican Americans
Author: Kyriakos S. Markides
Publisher: Center for Mexican American Studies
Total Pages: 170
Release: 1983
Genre: Social Science
ISBN:

OECD Reviews of Health Systems: Mexico 2016

OECD Reviews of Health Systems: Mexico 2016
Author: OECD
Publisher: OECD Publishing
Total Pages: 176
Release: 2016-01-07
Genre:
ISBN: 9264230491

Ten years after the introduction of publically-funded universal health insurance, the Mexican health system finds itself at a critical juncture.

Hispanics and the Future of America

Hispanics and the Future of America
Author: National Research Council
Publisher: National Academies Press
Total Pages: 502
Release: 2006-02-23
Genre: Social Science
ISBN: 0309164818

Hispanics and the Future of America presents details of the complex story of a population that varies in many dimensions, including national origin, immigration status, and generation. The papers in this volume draw on a wide variety of data sources to describe the contours of this population, from the perspectives of history, demography, geography, education, family, employment, economic well-being, health, and political engagement. They provide a rich source of information for researchers, policy makers, and others who want to better understand the fast-growing and diverse population that we call "Hispanic." The current period is a critical one for getting a better understanding of how Hispanics are being shaped by the U.S. experience. This will, in turn, affect the United States and the contours of the Hispanic future remain uncertain. The uncertainties include such issues as whether Hispanics, especially immigrants, improve their educational attainment and fluency in English and thereby improve their economic position; whether growing numbers of foreign-born Hispanics become citizens and achieve empowerment at the ballot box and through elected office; whether impending health problems are successfully averted; and whether Hispanics' geographic dispersal accelerates their spatial and social integration. The papers in this volume provide invaluable information to explore these issues.