Colorectal Cancer Awareness Month 2023: Diagnosis, Clinical Course, and Surgical Management of Metastatic Colorectal Cancer

Colorectal Cancer Awareness Month 2023: Diagnosis, Clinical Course, and Surgical Management of Metastatic Colorectal Cancer
Author: Aldo Rocca
Publisher: Frontiers Media SA
Total Pages: 134
Release: 2024-10-24
Genre: Medical
ISBN: 2832556000

March is Colorectal Cancer Awareness Month and at Frontiers in Oncology we want to highlight the recent discoveries in the field and raise awareness of the importance of early diagnosis, multidisciplinary management, and technological innovation support. Colorectal cancer (CRC) is the third most common cancer worldwide and represents one of the most relevant challenges for present and future global health, with 50 % of patients affected by CRC developing metastasis. Despite the introduction of novel therapeutic approaches and anticancer drugs, colorectal metastatic cancer (mCRC) continue to have a poor prognosis. In the last years, the extensive investigation on biomarkers that could identify patients at high risk for metastasis and predict the response to therapies has deeply impacted the therapeutic approaches to patients with mCRC. The most established biomarkers for mCRC are microsatellite instability (MSI) or mismatch repair deficiency (dMMR), HER2 amplification, RAS/BRAF mutations, and sidedness. Immune checkpoint inhibitors (ICIs) have been extensively used to treat patients with microsatellite unstable or mismatch repair-deficient (dMMR) CRC, while patients harboring a BRAFV600E mutation benefit from combination therapy with chemotherapy and immunotherapy drugs. The success of biomarker-driven patient selection to improve the therapeutic response and the overall survival of patients with mCRC highlights the imperative need for further research to identify novel biomarkers for better patient-tailored therapy.

Rectal Cancer Treatment

Rectal Cancer Treatment
Author: M.W. Büchler
Publisher: Springer Science & Business Media
Total Pages: 284
Release: 2005-10-11
Genre: Medical
ISBN: 3540274499

Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.

Diagnosis and Treatment Planning in Dentistry - E-Book

Diagnosis and Treatment Planning in Dentistry - E-Book
Author: Stephen J. Stefanac
Publisher: Elsevier Health Sciences
Total Pages: 543
Release: 2023-01-27
Genre: Medical
ISBN: 0323809782

**Selected for Doody's Core Titles® 2024 with "Essential Purchase" designation in Dentistry** Enhance your skills in patient assessment, oral diagnosis, and treatment planning! A full-color, all-in-one reference, Diagnosis and Treatment Planning in Dentistry, 4th Edition helps you create person-centered dental treatment plans for adolescent and adult patients. Using evidence-based research, this text shows how risk assessment, prognosis, and expected treatment outcomes factor into the planning process. Detailed coverage guides you through each phase of the treatment plan. New to this edition are chapters covering digital tools used in treatment planning and revised content in all chapters. The book renews a core section that describes how to plan and provide optimal oral health care for unique patient populations. Written by noted dentistry educators Stephen Stefanac and Samuel Nesbit, this must-have resource includes a fully searchable eBook version free with each print purchase. - Clear, logical organization builds your understanding with sections on comprehensive patient evaluation, the treatment planning process, the five phases of the treatment plan, and care planning for all patients. - What's the Evidence? boxes cite research articles affecting clinical decision-making and treatment planning strategies. - In Clinical Practice boxes summarize information on specific clinical situations for quick and easy review. - Ethics in Dentistry boxes address clinical situations where ethical decision making may be required. - Review questions summarize and reinforce the important concepts in each chapter. - 350 full-color illustrations depict important concepts. - NEW! Updated content in all chapters. - NEW! An eBook version is included with print purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Plus, additional videos and all-new case-based practice quizzes for each chapter. - NEW! Digital Tools chapter focuses on the use of digital tools in diagnosis and treatment planning.

Genetics of Colorectal Cancer

Genetics of Colorectal Cancer
Author: John D. Potter
Publisher: Springer
Total Pages: 309
Release: 2008-12-08
Genre: Medical
ISBN: 9780387095677

Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.

Chicken Soup for the Soul: Hope & Healing for Your Breast Cancer Journey

Chicken Soup for the Soul: Hope & Healing for Your Breast Cancer Journey
Author: Dr. Julie Silver
Publisher: Simon and Schuster
Total Pages: 206
Release: 2012-09-04
Genre: Health & Fitness
ISBN: 1611592119

Chicken Soup for the Soul: Hope & Healing for Your Breast Cancer Journey will encourage comfort and encourage breast cancer patients and survivors with its inspiring stories and helpful medical information. A support group from breast cancer diagnosis through treatment to rehabilitation and recovery, this book combines inspiring Chicken Soup for the Soul stories written just for this book and accessible leading-edge medical information from Dr. Julie Silver of Harvard Medical School. Patients and survivors will find comfort, strength and hope.

CDC Yellow Book 2018: Health Information for International Travel

CDC Yellow Book 2018: Health Information for International Travel
Author: Centers for Disease Control and Prevention CDC
Publisher: Oxford University Press
Total Pages: 705
Release: 2017-04-17
Genre: Medical
ISBN: 0190628634

THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Hereditary Colorectal Cancer

Hereditary Colorectal Cancer
Author: Miguel A. Rodriguez-Bigas
Publisher: Springer Science & Business Media
Total Pages: 615
Release: 2010-09-10
Genre: Medical
ISBN: 144196603X

Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease.

Textbook of Emergency General Surgery

Textbook of Emergency General Surgery
Author: Federico Coccolini
Publisher: Springer Nature
Total Pages: 1707
Release: 2023-06-06
Genre: Medical
ISBN: 3031225996

This text aims to provide a comprehensive review of general emergency surgery, the branch of medicine that treats patients presenting to the hospital with a wide variety of emergency conditions. It includes a section focusing on clinical aspects, management, logistics, patient cohorts and perioperative considerations in the context of general emergency surgery and trauma. Other sections describe various conditions and diseases in specific anatomical structures to enable readers to easily find the information they need. Written and edited by international experts and opinion leaders in the field, this book is a valuable reference resource for general and emergency surgeons, trauma surgeons, emergency physicians and nurses. It will also be of interest to residents, students and all other healthcare professionals involved in the management of emergency surgical patients.

Care Without Coverage

Care Without Coverage
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 213
Release: 2002-06-20
Genre: Medical
ISBN: 0309083435

Many Americans believe that people who lack health insurance somehow get the care they really need. Care Without Coverage examines the real consequences for adults who lack health insurance. The study presents findings in the areas of prevention and screening, cancer, chronic illness, hospital-based care, and general health status. The committee looked at the consequences of being uninsured for people suffering from cancer, diabetes, HIV infection and AIDS, heart and kidney disease, mental illness, traumatic injuries, and heart attacks. It focused on the roughly 30 million-one in seven-working-age Americans without health insurance. This group does not include the population over 65 that is covered by Medicare or the nearly 10 million children who are uninsured in this country. The main findings of the report are that working-age Americans without health insurance are more likely to receive too little medical care and receive it too late; be sicker and die sooner; and receive poorer care when they are in the hospital, even for acute situations like a motor vehicle crash.