Frontiers in Clinical Drug Research - Diabetes and Obesity

Frontiers in Clinical Drug Research - Diabetes and Obesity
Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
Total Pages: 249
Release: 2016-06-07
Genre: Science
ISBN: 1681081857

Frontiers in Clinical Drug Research – Diabetes and Obesity is an eBook series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research. The second volume of this series features 7 reviews presenting updates on hormones and several classes of drugs: -Osteocalcin action in glucose metabolism -Sodium-glucose co-transporter 2 (SGLT2) inhibitors -Glucagon-like peptide-1 (GLP-1) mimetics -Dipeptidyl peptidase 4 (DPP-4) inhibitors -New drugs in clinical trial and commercial phases

Clinical Research in Diabetes and Obesity, Volume 2

Clinical Research in Diabetes and Obesity, Volume 2
Author: Boris Draznin
Publisher: Springer Science & Business Media
Total Pages: 397
Release: 2013-03-09
Genre: Medical
ISBN: 1475739060

An unprecedented compilation of state-of-the-art advances in clinical research by premier clinical scientists around the world. This volume discusses the methods of clinical research and the interpretation of their results in studies of normal individuals, obese subjects, and patients with diabetes mellitus. Along the way, the authoritative contributors writing here illuminate how changes in the hormone action and substrate metabolism of healthy humans may lead to obesity and noninsulin-dependent diabetes mellitus.

Obesity and Diabetes

Obesity and Diabetes
Author: Joel Faintuch
Publisher: Springer
Total Pages: 286
Release: 2014-12-29
Genre: Medical
ISBN: 3319131265

This timely and clinically oriented book uniquely addresses the entire spectrum of treatment for severe obesity and diabetes. It thoroughly examines all aspects from robotic surgery to cell therapy, from the latest antidiabetic drugs to endoscopic procedures and devices, from appetite-inhibiting signals and nutrients to gastric arterial embolization. It offers objective and authoritative information for practicing professionals; not only are successful interventions discussed and updated, but cutting-edge and experimental pathways are also anticipated. Obesity is the foremost nutritional challenge worldwide. Its companion is type-2 diabetes, the most prevalent metabolic disease. Together they represent the diabesity epidemic, which is draining resources, overwhelming healthcare facilities, and impacting life expectancy and quality of life everywhere. No country has been spared, and most medical specialties have been affected. Many books focus on the surgical options for obesity and diabetes, namely bariatric and metabolic operations. Information on the clinical and pharmacological treatment is also available, conveyed by standard texts on internal medicine and endocrinology. Yet endoscopic maneuvers and prostheses, cell therapy for diabetes, and other innovative approaches are hard to come by, as conventional texts overlook such therapies. This timely publication bridges the gaps between all different therapeutic options, also covering advances in the conservative, surgical and parasurgical domains. This book will appeal to seasoned specialists, students and healthcare professionals in training alike.

Obesity, Type 2 Diabetes and the Adipose Organ

Obesity, Type 2 Diabetes and the Adipose Organ
Author: Saverio Cinti
Publisher:
Total Pages: 455
Release: 2018
Genre: Adipose tissues
ISBN: 9783319405216

This richly illustrated book provides a detailed description of the gross anatomy, light microscopy, immunohistochemistry, and electron microscopy of the adipose organ, which comprises subcutaneous and visceral fat depots. Findings in mice of differing genetic backgrounds (obesity prone and resistant) and maintained in standard and various physiologic and pathologic conditions are presented. The latter conditions include chronic cold exposure, warm exposure, fasting, pregnancy-lactation, and obesity. Features of the fetal adipose organ are described in a separate chapter, and results from transgenic mice are also presented when relevant. The human adipose organ is addressed in several chapters that include magnetic resonance and fetal findings. Most of the results regarding the adipose organ anatomy in different physiologic conditions are new, and the story of pink adipocytes (white-to-pink transdifferentiation) is quite innovative. The concept of using browning of the adipose organ as a therapeutic tool for obesity must take into consideration the anatomic and morphologic aspects described here, and the study of pink adipocytes could lead to a better comprehension of breast cancer tumor biology. This book will be of interest to all scientists who deal with obesity and related disorders.

Type 2 Diabetes and Dementia

Type 2 Diabetes and Dementia
Author: Velandai Srikanth
Publisher: Academic Press
Total Pages: 322
Release: 2018-02-09
Genre: Medical
ISBN: 0128096942

Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology. - Presents a comprehensive overview that details the relationship between diabetes, dementia and the future of medicine and therapeutics - Written for researchers and clinicians in neurology, neuroscience, geriatric medicine and endocrinology - Includes topics ranging from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment, prevention strategies and therapeutic applications

Psychosocial Care for People with Diabetes

Psychosocial Care for People with Diabetes
Author: Deborah Young-Hyman
Publisher: American Diabetes Association
Total Pages: 330
Release: 2012-12-25
Genre: Psychology
ISBN: 1580404391

Psychosocial Care for People with Diabetes describes the major psychosocial issues which impact living with and self-management of diabetes and its related diseases, and provides treatment recommendations based on proven interventions and expert opinion. The book is comprehensive and provides the practitioner with guidelines to access and prescribe treatment for psychosocial problems commonly associated with living with diabetes.

International Textbook of Diabetes Mellitus

International Textbook of Diabetes Mellitus
Author: R. A. DeFronzo
Publisher: John Wiley & Sons
Total Pages: 1200
Release: 2015-03-11
Genre: Medical
ISBN: 1118387678

The International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions. Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach. Sections covered include epidemiology, diagnosis, pathogenesis, management and complications of diabetes and public health issues worldwide. It incorporates a vast amount of new data regarding the scientific understanding and clinical management of this disease, with each new edition always reflecting the substantial advances in the field. Whereas other diabetes textbooks are primarily clinical with less focus on the basic science behind diabetes, ITDM's primary philosophy has always been to comprehensively cover the basic science of metabolism, linking this closely to the pathophysiology and clinical aspects of the disease. Edited by four world-famous diabetes specialists, the book is divided into 13 sections, each section edited by a section editor of major international prominence. As well as covering all aspects of diabetes, from epidemiology and pathophysiology to the management of the condition and the complications that arise, this fourth edition also includes two new sections on NAFLD, NASH and non-traditional associations with diabetes, and clinical trial evidence in diabetes. This fourth edition of an internationally recognised textbook will once again provide all those involved in diabetes research and development, as well as diabetes specialists with the most comprehensive scientific reference book on diabetes available.

Obesity and Diabetes

Obesity and Diabetes
Author: Anthony H. Barnett
Publisher: John Wiley & Sons
Total Pages: 324
Release: 2005-04-08
Genre: Medical
ISBN: 0470011092

Obesity has become the most common chronic disease of the present day, with significant increases in prevalence in populations across the world and all age groups. This has resulted in a dramatic increase in obesity-related metabolic and cardiovascular complications, making it an important public health issue. Type 2 diabetes associated with obesity or 'diabesity' is today the most common form of type 2 diabetes. It is also associated with a number of other cardiovascular risk factors, which constitute the metabolic syndrome. Effective management of 'diabesity' is crucial to the reduction of morbidity and premature mortality due to cardiovascular disease. This book comprises chapters written by leading international experts on various aspects of obesity-related diabetes. As a practical reference guide, it is suitable for all professionals with an interest in this field. Emerging problems such as childhood 'diabesity' and the impact of obesity on polycystic ovary syndrome will be of interest not only to paediatricians and endocrinologists, but also to general practitioners and other healthcare professionals. The contemporary approach to the clinical assessment of obesity and its management in both primary and secondary care settings is also described.

Diabetes: from Research to Clinical Practice

Diabetes: from Research to Clinical Practice
Author: Md. Shahidul Islam
Publisher: Springer Nature
Total Pages: 582
Release: 2020-11-06
Genre: Medical
ISBN: 3030510891

Diabetes mellitus is a major public health problem affecting over 415 million people in the world. Extensive research over the decades and the recent discovery of new medicines have revolutionized our understanding and treatment of both type 2 diabetes and type 1 diabetes mellitus. This book contains selected topics that describe recent advances in research, and state of the art treatment of the two types of diabetes mellitus and their complications. The topics encompass epidemiology and pathogenesis of diabetes, clinical features, diagnosis and treatment of diabetes and related complications. The chapters contain essential background materials, as well as recent advances in researches in different aspects of diabetes mellitus. The books is expected to be useful for researchers, research students, as well as for the clinicians engaged in diabetes care and diabetes research.

The Diabetes Code

The Diabetes Code
Author: Dr. Jason Fung
Publisher: Greystone Books Ltd
Total Pages: 245
Release: 2018-04-03
Genre: Health & Fitness
ISBN: 1771642661

FROM NEW YORK TIMES BESTSELLING AUTHOR DR. JASON FUNG • “The doctor who invented intermittent fasting.” —The Daily Mail “Dr. Fung reveals how [type 2 diabetes] can be prevented and also reversed using natural dietary methods instead of medications … This is an important and timely book. Highly recommended.” —Dr. Mark Hyman, author of The Pegan Diet “Dr. Jason Fung has done it again. … Get this book!” —Dr. Steven R. Gundry, author of The Plant Paradox Everything you believe about treating type 2 diabetes is wrong. Today, most doctors, dietitians, and even diabetes specialists consider type 2 diabetes to be a chronic and progressive disease—a life sentence with no possibility of parole. But the truth, as Dr. Fung reveals in this groundbreaking book, is that type 2 diabetes is reversible. Writing with clear, persuasive language, Dr. Fung explains why conventional treatments that rely on insulin or other blood-glucose-lowering drugs can actually exacerbate the problem, leading to significant weight gain and even heart disease. The only way to treat type 2 diabetes effectively, he argues, is proper dieting and intermittent fasting—not medication. “The Diabetes Code is unabashedly provocative yet practical ... a clear blueprint for everyone to take control of their blood sugar, their health, and their lives.”—Dr. Will Cole, author of Intuitive Fasting