Clinical Pharmacology Of Sleep
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Author | : S.R. Pandi-Perumal |
Publisher | : Springer Science & Business Media |
Total Pages | : 266 |
Release | : 2006-02-16 |
Genre | : Medical |
ISBN | : 9783764372620 |
From the emergence of clinical sleep medicine marked by the establishment of the harbinger Stanford Sleep Disorders Clinic in the mid 1970s, offspring sleep dis- ders clinics and centers have grown exponentially with the recognition of the unmet diagnostic and treatment needs of the reservoir of patients suffering from sy- toms of what are now recognized and classi?ed as the nosology of human sleep disorders. Important in the growing armamentarium of treatment options for the sleep practitioner are both traditional and newer pharmacological agents, including over-the-counter, non-traditional, and prescription types, that are all used to treat, sometimes adjunctively, most clinically recognized sleep disorders. Although there are numerous academic treatises and reviews dealing with in- vidual treatment alternatives for the diversity of recognized sleep disorders, no one comprehensive resource, extant, has dealt with pharmacological treatment options and strategies for the major human sleep disorders associated with a panoply of symptomatic conditions. The present volume and its series of chapters individually focusing on a range of human conditions, from pediatric sleep disorders to sle- relateddisordersofindividualssufferingfromAlzheimer’sdementia,uniquelycover the wide range of human medical conditions amenable to thoughtfully sleep-related applied drug therapy. The Editors have brought together a superb group of internationally respected sleep clinicians, and researchers, that provide state-of-the-art analysis of the current basic and clinical perspective regarding the most common sleep disorders that are amenable to pharmacological treatment. In each chapter the authors outline a th- oughhistoricalbackgroundoftheparticulardisorderandreviewthebasicpre-clinical studies leading to current treatment options.
Author | : Sue Wilson |
Publisher | : Oxford University Press |
Total Pages | : 119 |
Release | : 2013-09-26 |
Genre | : Medical |
ISBN | : 0199674558 |
This pocketbook provides provide general psychiatrists and trainees with an updated text on the management of sleep disorders.
Author | : Anthony Kales |
Publisher | : Springer Science & Business Media |
Total Pages | : 603 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 3642578365 |
A review of the current state of the clinical and basic science of the pharmacology of sleep. The information provided ranges from a historical perspective to current concepts of sleep mechanisms, including the interaction between pharmacology and sleep-wake regulation and between chronopahrmacology and sleep-wake rhythms. For the first time in one single volume, both the basic mechanisms of sleep, and the basic and clinical aspects of the pharmacology of sleep are dealt with in a thorough, comprehensive and authoritative manner. The chapters, written by the foremost scientific authorities in this field, integrate the latest information on the basic mechanisms of drugs as they relate to their effects on sleep.
Author | : Anthony Kales |
Publisher | : Springer |
Total Pages | : 583 |
Release | : 2011-09-27 |
Genre | : Medical |
ISBN | : 9783642578373 |
A review of the current state of the clinical and basic science of the pharmacology of sleep. The information provided ranges from a historical perspective to current concepts of sleep mechanisms, including the interaction between pharmacology and sleep-wake regulation and between chronopahrmacology and sleep-wake rhythms. For the first time in one single volume, both the basic mechanisms of sleep, and the basic and clinical aspects of the pharmacology of sleep are dealt with in a thorough, comprehensive and authoritative manner. The chapters, written by the foremost scientific authorities in this field, integrate the latest information on the basic mechanisms of drugs as they relate to their effects on sleep.
Author | : Michael H. Silber |
Publisher | : CRC Press |
Total Pages | : 348 |
Release | : 2016-04-19 |
Genre | : Medical |
ISBN | : 1616310057 |
Co-authored by a neurologist, a psychiatrist, and a pulmonologist, Sleep Medicine in Clinical Practice reflects the cross-disciplinary nature in the clinical management of sleep disorders. The authors present an overview of sleep medicine including the physiological basis of sleep, diagnostic tools and possible therapeutic strategies, emphasizing t
Author | : Antonio Guglietta |
Publisher | : Springer |
Total Pages | : 291 |
Release | : 2014-11-28 |
Genre | : Medical |
ISBN | : 3319115146 |
Following reviews on sleep physiology, regulation, pharmacology, and the neuronal networks regulating sleep and awakening, as well as a classification of sleep disorders, this book presents a number of major breakthroughs in the treatment of those disorders. These include recently approved drugs for treating insomnia, such as Doxepin; variations on previously approved molecules, e.g. Zolpidem sublingual preparation; or new chemical entities in advanced stages of clinical development, e.g. Orexin antagonists. Further topics discussed include drugs acting on the GABA receptor, such as Lorediplon and Eszopiclone; the treatment of excessive daytime drowsiness with cell therapy and drugs such as Modafinil, Armodafinil and Sodium oxybate; and the use of Tasimelteon in the treatment of circadian sleep disorders.
Author | : Emmanuel H. During, M.D. |
Publisher | : American Psychiatric Pub |
Total Pages | : 422 |
Release | : 2020-07-29 |
Genre | : Medical |
ISBN | : 1615373004 |
"The importance of sleep for well-being and general and mental health is increasingly being recognized. Sleep complaints are commonly associated with mental disorders and are even part of the diagnostic criteria for some of them, such as mood and anxiety disorders and PTSD. The relationship between sleep and psychiatric disorders is intertwined and, in some cases, bidirectional. Anxiety, psychosis, and depression often result in reduced sleep quality (sleep fragmentation, experience of unpleasant, unrefreshing sleep), quantity (increased or reduced), or pattern (changes in sleep schedule, loss of sleep consistency). Reciprocally, sleep disorders can contribute to the exacerbation of psychiatric symptoms and independently affect the prognosis. Finally, most psychotropic drugs have an effect on sleep and arousal and can aggravate a preexisting sleep abnormality. This book aims to familiarize readers with current knowledge on the mutual effects of sleep and mental health and provide an integrated framework for students, clinicians, and researchers. Throughout its 18 chapters, it discusses the six main categories of sleep disorders: insomnia (Chapters 3-5), hypersomnia (Chapters 6-7), sleep-disordered breathing (Chapters 8-11), circadian disorders (Chapters 12-13), parasomnias (Chapters 14-16), and sleep-related movement disorders (Chapters 17-18)"--
Author | : Clete A. Kushida |
Publisher | : CRC Press |
Total Pages | : 618 |
Release | : 2004-11-16 |
Genre | : Medical |
ISBN | : 0203998006 |
Exploring the wide array of structures, substances, and environments that are primary factors in the initiation or inhibition of sleep, this reference highlights key findings from respected professionals around the globe on the social and economic burden of impaired performance, productivity, and safety arising from sleep deprivation-studying pharm
Author | : Jaime M. Monti |
Publisher | : Springer Science & Business Media |
Total Pages | : 501 |
Release | : 2010-09-28 |
Genre | : Medical |
ISBN | : 303460226X |
GABA (gamma-aminobutyric acid) is the main neurotransmitter regulating sleep. The majority of drugs presently in use for the treatment of sleep disorders act by enhancing GABAergic neuronal inhibition. The GABA system is, therefore, of prime clinical relevance for the therapy of insomnia. The focus of this volume is on the neuropsychopharmacology and the clinical impact of the GABA system in regulating sleep and wakefulness. It presents molecular, neuropharmacological, systems-biological and clinical approaches to the understanding of the mechanism of action of GABA and GABAergic drugs. It also explores the role of GABA in the basic drives that affect sleep, and the influences that adapt sleep and wakefulness to external events.
Author | : Malcolm Lader |
Publisher | : Springer Science & Business Media |
Total Pages | : 319 |
Release | : 2009-11-06 |
Genre | : Medical |
ISBN | : 0387276823 |
Many recent discoveries in both laboratory and clinical settings have greatly increased our understanding of sleep medicine and the relevant psychopharmacology. This timely book serves to present updated information about the neuropsychopharmacology of sleep as this field enters mainstream psychiatry, neurology and medicine This volume has assembled articles that summarize and review carefully, a chosen selection of the latest discoveries concerning sleep medicine, sleep physiology and sleep pharmacology. Outstanding contributions have been sought from acknowledged experts in their respective fields. The goal of the volume is to present the more recent developments and advances in the fields of sleep and neuropsychopharmacology, as well as to provide a context for considering them both in depth and from multidisciplinary perspectives. This volume brings together the collective expertise of clinicians and basic researchers who represent a range of interests in neuroscience, neuropharmacology, sleep physiology, and biological rhythms. Presenting a thoughtful balance of basic experimental and clinical facts and viewpoints, this book will serve as a foundation for understanding, and ultimately treating, sleep disorders.