Sperm Chromatin

Sperm Chromatin
Author: Armand Zini
Publisher: Springer Science & Business Media
Total Pages: 515
Release: 2011-08-04
Genre: Health & Fitness
ISBN: 1441968571

Sperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk of miscarriage. Although the exact causes of sperm DNA damage are unknown, it is clear that infertile men possess substantially higher levels of sperm DNA damage than do fertile men. Written by leading, internationally renowned clinicians and basic scientists with expertise in sperm DNA, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction provides readers with a thoughtful and comprehensive review of the biological and clinical significance of sperm DNA damage. The work covers the fundamental principles of sperm chromatin architecture and function, the proposed modes of DNA damage and repair, the tests of sperm DNA damage, the clinical aspects of DNA damage and the impact of DNA damage on reproductive outcome. Unlike any other title on the topic, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction is an invaluable addition to the literature and will serve as an indispensable resource for basic scientists with an interest in sperm biology and for urologists, gynecologists, reproductive endocrinologists, and embryologists working in the field of infertility.

Reproductomics

Reproductomics
Author: José A. Horcajadas
Publisher: Academic Press
Total Pages: 428
Release: 2018-07-13
Genre: Medical
ISBN: 0128126760

Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The –Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book Editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine. - Thoroughly discusses how genomics and other omics approaches aid clinicians in various areas of reproductive medicine - Identifies specific genomic and molecular factors of translational value in treating infertility and analyzing patient data - Features chapter contributions by leading international experts

Current Catalog

Current Catalog
Author: National Library of Medicine (U.S.)
Publisher:
Total Pages: 1550
Release:
Genre: Medicine
ISBN:

First multi-year cumulation covers six years: 1965-70.

Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies

Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies
Author: Sorin Hostiuc
Publisher: Academic Press
Total Pages: 434
Release: 2018-08-07
Genre: Medical
ISBN: 0128137657

Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies offers thorough discussions on preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, sex selection, predictive testing, secondary findings, embryo reduction and the moral status of the embryo, genetic enhancement, and the sharing of genetic data. Chapter contributions from leading bioethicists and clinicians encourage a global, holistic perspective on applied challenges and the moral questions relating the implementation of genetic reproductive technology. The book is an ideal resource for practitioners, regulators, lawmakers, clinical researchers, genetic counselors and graduate and medical students. As the Human Genome Project has triggered a technological revolution that has influenced nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, prenatal genetic testing, and gene therapy, this book presents a timely resource. - Provides practical analysis of the ethical issues raised by cutting-edge techniques and recent advances in prenatal and reproductive genetics - Contains contributions from leading bioethicists and clinicians who offer a global, holistic perspective on applied challenges and moral questions relating to genetic and genomic reproductive technology - Discusses preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, ethical issues, and more

Proceedings of 7th International Conference and Exhibition on Cell and Gene Therapy 2018

Proceedings of 7th International Conference and Exhibition on Cell and Gene Therapy 2018
Author: ConferenceSeries
Publisher: ConferenceSeries
Total Pages: 84
Release:
Genre:
ISBN:

March 15-16, 2018 London,UK Key Topics : Stem Cell Therapies, Cell Culture and Bioprocessing, Viral Gene Therapy, Gene and Cell Therapy for Rare & Common Diseases, Tissue Science & Regenerative Medicine, Molecular Basis of Epigenetics, Clinical Trials on Cell & Gene Therapy, Cell Science and Stem Cell Research, Bioengineering Therapeutics, Nano Therapy, Gene Editing Technology, Advanced Gene Therapeutics, Genetics & Genomic Medicine, Ethical Issues in Cell and Gene Therapy, Markets & Future Prospects for Cell & Gene Therapy, Cell Therapy, Gene Therapy, Cell Therapy of Cardiovascular Disorders, Cell Therapy for Neurological Disorders, Regulatory and Safety Aspects of Cell and Gene Therapy, Commercialization,

Clinical Management of Male Infertility

Clinical Management of Male Infertility
Author: Giorgio Cavallini
Publisher: Springer
Total Pages: 180
Release: 2014-10-20
Genre: Health & Fitness
ISBN: 3319085034

This book provides andrologists and other practitioners with reliable, up-to-date information on all aspects of male infertility and is designed to assist in the clinical management of patients. Clear guidance is offered on classification of infertility, sperm analysis interpretation and diagnosis. The full range of types and causes of male infertility are then discussed in depth. Particular attention is devoted to poorly understood conditions such as unexplained couple infertility and idiopathic male infertility, but the roles of diverse disorders, health and lifestyle factors and environmental pollution are also fully explored. Research considered stimulating for the reader is highlighted, reflecting the fascinating and controversial nature of the field. International treatment guidelines are presented and the role of diet and dietary supplements is discussed in view of their increasing importance. Clinicians will find that the book’s straightforward approach ensures that it can be easily and rapidly consulted.

Proceedings of 3rd International Conference on Advanced Clinical Research and Clinical Trials 2017

Proceedings of 3rd International Conference on Advanced Clinical Research and Clinical Trials 2017
Author: ConferenceSeries
Publisher: ConferenceSeries
Total Pages: 80
Release:
Genre:
ISBN:

September 20-21, 2017 Dublin, Ireland Key Topics : Innovations in Pre-clinical Research, Stem Cell & Oncology Clinical Research, Design of Clinical Studies and Trials, Conducts of Clinical Trials, Biomedical Devices Clinical Research, Clinical Research and Trials on AIDS, Clinical Trials on Different Diseases, Clinical Data Management and Statistics, Clinical Trials in Developing Countries, Innovations in Clinical Trials, Future of Clinical Trials, GCP Learning and Best Practices, Risk Management at Research Site, Bioethics and Quality Regulation, Pharmacovigilance and Drug Safety, Clinical and Medical Case Reports, Transforming Trial Methodologies, Diabetes & Gastroenterology Clinical Research, Current Regulatory Trends in Drug Development, Clinical Nursing Research,

Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health

Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health
Author: Suresh C Sikka
Publisher: Academic Press
Total Pages: 638
Release: 2017-11-14
Genre: Medical
ISBN: 0128013133

Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health is structured into two parts related to men's reproductive and sexual health with eight sections designed to enable a logical flow of such knowledge. The book is focused on the biology of key organs involved in male reproduction and the environmental influences affecting their functions with particular emphasis on clinical aspects. Individual chapters within the book range from basic to translational aspects, but all hold clinical relevance. This is an essential reference for those working and learning in the field of human reproduction, reproductive toxicology and environmental influences on reproductive and sexual health. - Brings together the leading authorities working in the field of male reproduction and sexual health and how the environment affects these issues - Provides guidelines and reference values of various reproductive hormones, semen parameters, inclusion/exclusion criteria for clinical trials - Discover the most efficient methods by which to design clinical protocols for sperm safety studies and reproductive toxicology trials