Chromogranins: from Cell Biology to Physiology and Biomedicine

Chromogranins: from Cell Biology to Physiology and Biomedicine
Author: Tommaso Angelone
Publisher: Springer
Total Pages: 271
Release: 2017-11-09
Genre: Medical
ISBN: 3319583387

The volume is designed to provide an integrated overview of the results from the last fifteen years of research on Chromogranins in relation to cell biology, physiology and biomedicine. The different chapters highlight novel activities of these proteins, including their role in granule biogenesis, hormone co-storage, stimulus-processing-secretion coupling, autonomic sympathetic/parasympathetic balance, immune and cardiocirculatory function, and the response to stress. Biomedical aspects are also illustrated with focus on the prognostic and diagnostic significance of Chromogranin in the presence of tumors, cardiovascular diseases and inflammatory conditions. The volume is of interest for laboratory and clinical scientists, PhD and Post-doc students that will be inspired to go deep inside the molecular, biochemical, physiological, pharmacological and clinical aspects of these fascinating multifaceted proteins.

Calcium Study to Alzheimer's Therapeutics

Calcium Study to Alzheimer's Therapeutics
Author: Seung Hyun Yoo
Publisher: Cambridge Scholars Publishing
Total Pages: 491
Release: 2024-04-26
Genre: Science
ISBN: 1036404242

This book will be informative and challenging for scientists, enlightening and stimulating for intellectuals and serious students, and highly beneficial and interesting for Alzheimer’s workers and the public. The first half is a historical account of recent scientific discoveries on calcium (Ca2+) storage and control organelles in cells, explaining the major role of secretory granules in the cytoplasm and the newly identified nucleoplasmic Ca2+ store vesicles in the nucleus. The second half not only presents unprecedented and highly relevant information on the pathogenic process of Alzheimer’s disease and current research, but also introduces Alzheimer’s therapeutics, which is ready to proceed to clinical trials. In light of this, it contains valuable information which will greatly benefit Alzheimer’s workers, patients, the families, and anybody interested in Alzheimer’s disease.

Epidemiology of Endocrine Tumors

Epidemiology of Endocrine Tumors
Author: Jahangir Moini
Publisher: Elsevier
Total Pages: 570
Release: 2021-03-03
Genre: Medical
ISBN: 0128232668

Epidemiology of Endocrine Tumors brings current data and clinical research into one source for a multidisciplinary audience. The book discusses the prevalence, incidence, etiology, pathology, diagnosis and treatment of various endocrine tumors. With clear and focused writing, it is essential reading for healthcare professionals, endocrinologists, oncologists, and public health professionals. Users will be able to bridge the knowledge gap that exists in the comprehensive coverage surrounding the epidemiology of endocrine tumors. Globally, the prevalence and incidence of endocrine tumors is high. This audience needs a treatise where they can gain a broad overview of endocrine tumors with a focus on epidemiology. - Supplies information about the epidemiology of various endocrine tumors, both benign and malignant, to endocrinologists, oncologists and related health care professionals - Focuses on the impact upon costs and patient deaths due to complications of these tumors - Describes how endocrine tumors affect various age groups and ethnicities, discussing the prevention of endocrine tumors - Presents chapters on Cancer Problem, Specific Endocrine Tumors, Prevention, Detection and Diagnosis, and Treatment of Endocrine Tumors - Provides review questions with an answer key and detailed glossary

Handbook of Biologically Active Peptides

Handbook of Biologically Active Peptides
Author: Abba Kastin
Publisher: Academic Press
Total Pages: 2033
Release: 2013-01-26
Genre: Science
ISBN: 0123850967

Handbook of Biologically Active Peptides, Second Edition, is the definitive, indispensable reference for peptide researchers, biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and endocrinologists. Its chapters are designed to be a source for workers in the field and enable researchers working in a specific area to examine related areas outside their expertise. Peptides play a crucial role in many physiological processes, including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The second edition of Handbook of Biologically Active Peptides presents this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. - Presents all aspects of biologically active peptides in one resource - Features more than 20 sections spanning plant, bacterial, fungal, venom, and invertebrate peptides to general peptides - Includes immunological, inflammatory, cancer, vaccine, and neurotrophic peptides - Discusses peptide precursors, mRNA distribution, processing, and receptors, not just pathophysiological implications

Handbook of Neuroendocrinology

Handbook of Neuroendocrinology
Author: George Fink
Publisher: Academic Press
Total Pages: 895
Release: 2012
Genre: Medical
ISBN: 0123750970

Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.

Arterial Chemoreception

Arterial Chemoreception
Author: Colin A. Nurse
Publisher: Springer Science & Business Media
Total Pages: 399
Release: 2012-10-19
Genre: Medical
ISBN: 9400745834

Arterial chemoreceptors are unique structures which continuously monitor changes in arterial blood oxygen, carbon dioxide, glucose, and acid. Alterations in these gases are almost instantaneously sensed by arterial chemoreceptors and relayed into a physiological response which restores blood homeostasis. Arterial Chemoreception contains updated material regarding the physiology of the primary arterial chemoreceptor; the carotid body. Moreover, this book also explores tantalizing evidence regarding the contribution of the aortic bodies, chromaffin cells, lung neuroepithelial bodies, and brainstem areas involved in monitoring changes in blood gases. Furthermore this collection includes data showing the critical importance of these chemoreceptors in the pathophysiology of human disease and possible therapeutic treatments. This book is a required text for any researcher in the field of arterial chemoreception for years to come. It is also a critical text for physicians searching for bench-to-bedside treatments for heart failure, sleep apnea, and pulmonary hypertension.