Prospects for Chemoprevention of Colorectal Neoplasia

Prospects for Chemoprevention of Colorectal Neoplasia
Author: Andrew T. Chan
Publisher: Springer Science & Business Media
Total Pages: 186
Release: 2012-08-15
Genre: Medical
ISBN: 3642303315

The prevention of colorectal cancer is a subject of increasing medical importance, and there have been a number of promising recent developments. This book examines in detail important aspects of the current status and future prospects for chemoprevention of colorectal tumors. Research into the mechanisms that lead from early colorectal adenoma to colorectal cancer is discussed. The role and modes of action of available drugs such as celecoxib and sulindac are described, and recent data from aspirin trials are analyzed. In addition, the possible impact of nutritional agents with anti-inflammatory properties is considered, and strategies applicable in those with a high level of genetic risk are evaluated. An important feature of the book is its holistic perspective, making it relevant for gastroenterologists, internists, general practitioners, oncologists, colorectal and gastroenterological surgeons, and public health practitioners.

Chemoprevention of Colorectal Cancer

Chemoprevention of Colorectal Cancer
Author: R. Vijayabharathi
Publisher: Independent Author
Total Pages: 0
Release: 2023-04-05
Genre: Medical
ISBN: 9781805281429

Chemoprevention of Colorectal Cancer" by R. Vijayabharathi is a book that focuses on the use of 5,7-dimethoxy flavone as a chemopreventive agent for colorectal cancer. Colorectal cancer is the third most commonly diagnosed cancer worldwide and is a leading cause of cancer-related deaths. The book presents an in-depth analysis of the chemopreventive effects of 5,7-dimethoxy flavone on colorectal cancer. The book discusses the various factors that contribute to the development of colorectal cancer, including diet, lifestyle, and genetics. The author explores the role of 5,7-dimethoxy flavone in preventing the development and progression of colorectal cancer by targeting various signaling pathways and molecular targets involved in cancer development. The book also covers the latest research on the use of 5,7-dimethoxy flavone in animal models of colorectal cancer and clinical trials. The author presents the results of these studies and discusses the potential of 5,7-dimethoxy flavone as a safe and effective chemopreventive agent for colorectal cancer. Overall, "Chemoprevention of Colorectal Cancer" is a valuable resource for researchers, academics, and professionals interested in the prevention and treatment of colorectal cancer. The author's expertise in this field makes this book an authoritative reference for anyone interested in the use of 5,7-dimethoxy flavone as a chemopreventive agent for colorectal cancer.

Cancer Chemoprevention

Cancer Chemoprevention
Author: Lee Wattenberg
Publisher: CRC Press
Total Pages: 654
Release: 1992-08-20
Genre: Medical
ISBN: 9780849347153

The ultimate goal of cancer chemoprevention research and development is the identification of pharmaceutical or dietary constituents that will prevent cancer. Cancer Chemoprevention presents the proceedings of a large workshop on cancer chemoprevention that highlights the latest knowledge in the field, in addition to issues and ideas concerning future directions. Retinoids, sulfur compounds, and a large number of many naturally occurring cancer inhibitors in the diet are discussed, including green tea, garlic constituents, citrus fruit oils, and beans and seeds containing protease inhibitors. Compounds that may prevent the formation of carcinogens in food are covered, and the mechanisms by which chemical or dietary agencts produce cancer inhibitors are discussed.

Natural Products for Cancer Chemoprevention

Natural Products for Cancer Chemoprevention
Author: John M. Pezzuto
Publisher: Springer Nature
Total Pages: 639
Release: 2020-04-03
Genre: Medical
ISBN: 3030398552

This book discusses the efficacy of various naturally occurring chemopreventive agents in preventing or delaying cancer. It focuses on the holistic chemopreventive concept, demonstrating the relevant response is the combined effect of a series of compounds that alone have been shown to have some effect in different experimental models. Written by leading experts in the field, the contributions provide details of research on various chemopreventive agents. Offering insights into the unique molecular targets and mechanisms, safety issues, molecular efficacy, and occurrence in nature of these compounds, the book is a valuable resource for all scientists working in biomedicine, and specifically in cancer research.

Chemoprevention of Cancer

Chemoprevention of Cancer
Author: H.-J. Senn
Publisher: Springer Science & Business Media
Total Pages: 205
Release: 2012-12-06
Genre: Medical
ISBN: 3642599451

Pharmacologic interventions to prevent the evolution of human cancers are still in its infancy, although a good number o- mostly controlled - clinical studies have been performed in the past two decades. However, regarding the partially stagnating therapeutic results of major epithelial cancer types such as breast-, lung-, colon- and ENT-cancer types, the problem of in terference with the evolution of disease at a preclinical level is an intriguing one, and the field seems to develop into one of the fastest growing domaines of modern oncology. This process is fa cilitated by the developments of molecular on co-genetics and the gowing existence of family cancer units, allowing to better identi fy and inform respective high risk groups, thus enabling re searchers and clinicians to more realistically target their chemo preventive efforts to the true populations at risk. On this changing background, the newly formed International Society of Cancer Chemoprevention (ISCaC) together with the Swiss Cancer League and the Interdisciplinary Oncology Center of St. Gallen/Switzerland organized an international Symposium in September 1997, inviting basic researchers, epidemiologists and clinical oncologists of related disciplines to discuss pertinent issues of experimental and clinical chemo- and bio-prevention in a scientific workshop.