The Biological Chemistry of Nickel

The Biological Chemistry of Nickel
Author: Deborah Zamble
Publisher: Royal Society of Chemistry
Total Pages: 397
Release: 2017-04-04
Genre: Science
ISBN: 1782624988

An essential text for biochemists, biologists and medicinal chemists, this book provides a comprehensive review of the latest findings in nickel biology, covering the function, biochemistry, toxicology and medical applications of nickel systems.

Biochemistry of Nickel

Biochemistry of Nickel
Author: Robert P. Hausinger
Publisher: Springer Science & Business Media
Total Pages: 286
Release: 2013-06-29
Genre: Science
ISBN: 1475794355

In this timely monograph, the author summarizes the rapidly growing body of knowledge regarding nickel by providing a balanced discussion of its harmful and beneficial effects. Coverage includes a history of nickel; the chemistry of nickel, descriptions of the four known enzymes which contain nickel; and nickel metabolism in microbes, plants, and animals. Taken as a whole, Dr. Hausinger's work will highlight key features of this important element and help define future research.

Model Complexes for Nickel Containing Enzymes

Model Complexes for Nickel Containing Enzymes
Author: Joshua Robert Zimmerman
Publisher:
Total Pages: 209
Release: 2009
Genre: Electronic dissertations
ISBN:

Carbon Monoxide Dehydrogenase / Acetyl CoA Synthase (CODH/ACS) is a bifunctional enzyme that catalyzes the reduction of CO2́2 to CO and the assembly of Acetyl CoA. The A-cluster active site, which catalyzes the Acetyl CoA synthesis, contains a Fe-S cubane bridged by a cysteine thiolate to a dinuclear Ni(℗æ-S)2́2Ni cluster (Fig. 1). The proximal nickel, Nip, has S2́3X coordination, while the distal nickel, Nid, has N2́2S2́2 coordination. This project focuses on the synthesis of model complexes for the asymmetric dinuclear metal center in order to understand the electronic characteristics of this cluster and investigate the feasibility of proposed intermediates. The initial target compound is shown in Figure 2. We have developed an efficient method for synthesizing metal complexes with mixed N/S coordination through the use of 2-2'-dithiodibenzaldehyde, DTDB. Symmetric nickel complexes with NS2́3 coordination have previously been synthesized using DTDB and various bidentate NS ligands. Herein we present our results upon incorporating N,N-dimethylethylenediamine into this methodology.

Comprehensive Inorganic Chemistry II

Comprehensive Inorganic Chemistry II
Author:
Publisher: Newnes
Total Pages: 7694
Release: 2013-07-23
Genre: Science
ISBN: 0080965296

Comprehensive Inorganic Chemistry II, Nine Volume Set reviews and examines topics of relevance to today’s inorganic chemists. Covering more interdisciplinary and high impact areas, Comprehensive Inorganic Chemistry II includes biological inorganic chemistry, solid state chemistry, materials chemistry, and nanoscience. The work is designed to follow on, with a different viewpoint and format, from our 1973 work, Comprehensive Inorganic Chemistry, edited by Bailar, Emeléus, Nyholm, and Trotman-Dickenson, which has received over 2,000 citations. The new work will also complement other recent Elsevier works in this area, Comprehensive Coordination Chemistry and Comprehensive Organometallic Chemistry, to form a trio of works covering the whole of modern inorganic chemistry. Chapters are designed to provide a valuable, long-standing scientific resource for both advanced students new to an area and researchers who need further background or answers to a particular problem on the elements, their compounds, or applications. Chapters are written by teams of leading experts, under the guidance of the Volume Editors and the Editors-in-Chief. The articles are written at a level that allows undergraduate students to understand the material, while providing active researchers with a ready reference resource for information in the field. The chapters will not provide basic data on the elements, which is available from many sources (and the original work), but instead concentrate on applications of the elements and their compounds. Provides a comprehensive review which serves to put many advances in perspective and allows the reader to make connections to related fields, such as: biological inorganic chemistry, materials chemistry, solid state chemistry and nanoscience Inorganic chemistry is rapidly developing, which brings about the need for a reference resource such as this that summarise recent developments and simultaneously provide background information Forms the new definitive source for researchers interested in elements and their applications; completely replacing the highly cited first edition, which published in 1973

Encyclopedia of Geobiology

Encyclopedia of Geobiology
Author: Joachim Reitner
Publisher: Springer
Total Pages: 927
Release: 2011-03-10
Genre: Science
ISBN: 9781402092138

The interplay between Geology and Biology has shaped the Earth from the early Precambrian, 4 billion years ago. Moving beyond the borders of the classical core disciplines, Geobiology strives to identify chains of cause-and-effect and synergisms between the geo- and the biospheres that have been driving the evolution of life in modern and ancient environments. Combining modern methods, geobiological information can be extracted not only from visible remains of organisms, but also from organic molecules, rock fabrics, minerals, isotopes and other tracers. An understanding of these processes and their signatures reveals enormous applied potentials with respect to issues of environment protection, public health, energy and resource management. The Encyclopedia of Geobiology has been designed to act as a key reference for students, researchers, teachers, and the informed public and to provide basic, but comprehensible knowledge on this rapidly expanding discipline that sits at the interface between modern geo- and biosciences.